RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on: April 22,2024

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on:April 22,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on: May 08,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on:May 08,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on: March 07,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on:March 07,2024

A plant-based compound that inhibits reactivation of the HIV viral reservoir, giving the immune system a break

by The Wistar InstituteOverview of HIV inhibitor screening strategy and identification of (–)-hopeaphenol. (A) Representative flow cytometry examples of HIV-GFP reporter expression in unstimulate

Updated on: May 05,2024

A plant-based compound that inhibits reactivation of the HIV viral reservoir, giving the immune system a break

by The Wistar InstituteOverview of HIV inhibitor screening strategy and identification of (–)-hopeaphenol. (A) Representative flow cytometry examples of HIV-GFP reporter expression in unstimulate

Updated on:May 05,2024

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on: March 19,2024

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on:March 19,2024

Criteria to predict cytokine storm in COVID-19 patients identified

by Temple UniversityCredit: CC0 Public DomainLike a cold front that moves in, setting the stage for severe weather, coronavirus infection triggers showers of infection-fighting immune molecules—s

Updated on: June 06,2024

Criteria to predict cytokine storm in COVID-19 patients identified

by Temple UniversityCredit: CC0 Public DomainLike a cold front that moves in, setting the stage for severe weather, coronavirus infection triggers showers of infection-fighting immune molecules—s

Updated on:June 06,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024

New approach to arthritis treatment could avoid serious side-effects

by Queen Mary, University of London(Medical Xpress)—A new approach to arthritis treatment, which avoids unforeseen side-effects by delivering drugs exclusively to affected inflamed joints, has be

Updated on: March 26,2024

New approach to arthritis treatment could avoid serious side-effects

by Queen Mary, University of London(Medical Xpress)—A new approach to arthritis treatment, which avoids unforeseen side-effects by delivering drugs exclusively to affected inflamed joints, has be

Updated on:March 26,2024

COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

by Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainViruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strain

Updated on: April 10,2024

COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

by Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainViruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strain

Updated on:April 10,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on: April 10,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on:April 10,2024

New assay may lead to a cure for debilitating inflammatory joint disease

by New York University School of MedicineGregg Silverman, MD, Professor, Departments of Medicine and Pathology at NYU Langone Medical Center, and Director of its Musculoskeletal Center of Excelle

Updated on: May 13,2024

New assay may lead to a cure for debilitating inflammatory joint disease

by New York University School of MedicineGregg Silverman, MD, Professor, Departments of Medicine and Pathology at NYU Langone Medical Center, and Director of its Musculoskeletal Center of Excelle

Updated on:May 13,2024

World's first CAR-T cell therapy for a child with lupus

byFriedrich–Alexander University Erlangen–NurnbergThe medical team and their patient (left to right): Dr. Tobias Krickau, Dr. Nora Naumann-Bartsch, Patientin Uresa A., Prof. Dr. Markus Metzler,

Updated on: July 09,2024

World's first CAR-T cell therapy for a child with lupus

byFriedrich–Alexander University Erlangen–NurnbergThe medical team and their patient (left to right): Dr. Tobias Krickau, Dr. Nora Naumann-Bartsch, Patientin Uresa A., Prof. Dr. Markus Metzler,

Updated on:July 09,2024