Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on: July 25,2024

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

by Higher Education PressThe mechanism of action of pyruvate by targeting cPLA2 and inhibiting cPLA2-mediated downstream signaling. Credit: Sadaf Hasan, Nabil Ghani, Xiangli Zhao, Julia Good, Amanda H

Updated on:July 25,2024

Hunger signals, including those from endogenous cannabinoids, mapped in the brain

by Aran Sullivan,Vanderbilt UniversityCredit: Pixabay/CC0 Public DomainCannabis is well-known for having an effect on eating behaviors. However, how the natural cannabinoid molecules found in th

Updated on: February 05,2024

Hunger signals, including those from endogenous cannabinoids, mapped in the brain

by Aran Sullivan,Vanderbilt UniversityCredit: Pixabay/CC0 Public DomainCannabis is well-known for having an effect on eating behaviors. However, how the natural cannabinoid molecules found in th

Updated on:February 05,2024

Exercise hormone halts Parkinson's disease symptoms in mouse study

by Johns Hopkins University School of MedicineBlood-brain penetration of intravenously injected irisin. (A, B) Two weeks after intrastriatal ?-syn PFF injection, the mice were injected with AAV8-

Updated on: February 21,2024

Exercise hormone halts Parkinson's disease symptoms in mouse study

by Johns Hopkins University School of MedicineBlood-brain penetration of intravenously injected irisin. (A, B) Two weeks after intrastriatal ?-syn PFF injection, the mice were injected with AAV8-

Updated on:February 21,2024

For diabetes and liver cancer, study suggests new screening guidelines

by Krista Conger,Stanford University Medical CenterCollagen fibers in a three-dimensional hydrogel (left panel). When advanced glycation end products—a byproduct of poorly controlled diabetes—ar

Updated on: March 14,2024

For diabetes and liver cancer, study suggests new screening guidelines

by Krista Conger,Stanford University Medical CenterCollagen fibers in a three-dimensional hydrogel (left panel). When advanced glycation end products—a byproduct of poorly controlled diabetes—ar

Updated on:March 14,2024

Does maternal obesity during pregnancy impact offspring's liver and skeletal muscle metabolism?

by WileyCredit:The FASEB Journal(2022). DOI: 10.1096/fj.202201473RA recent study inThe FASEB Journalhas identified metabolic perturbations in the liver and skeletal muscle

Updated on: February 19,2024

Does maternal obesity during pregnancy impact offspring's liver and skeletal muscle metabolism?

by WileyCredit:The FASEB Journal(2022). DOI: 10.1096/fj.202201473RA recent study inThe FASEB Journalhas identified metabolic perturbations in the liver and skeletal muscle

Updated on:February 19,2024

Scientists search for new treatment target for diabetic retinopathy

byMedical College of Georgia at Augusta UniversityCredit: Unsplash/CC0 Public DomainScientists at the Medical College of Georgia at Augusta University are searching for a new treatment target fo

Updated on: September 13,2024

Scientists search for new treatment target for diabetic retinopathy

byMedical College of Georgia at Augusta UniversityCredit: Unsplash/CC0 Public DomainScientists at the Medical College of Georgia at Augusta University are searching for a new treatment target fo

Updated on:September 13,2024

Obesity alters molecular architecture of liver cells. Repairing structure reverses metabolic disease

by Harvard School of Public HealthThe endoplasmic reticulum (ER) is white and lipid droplets appear yellow In this three-dimensional image of the interior of a diseased mouse liver cell created b

Updated on: January 31,2024

Obesity alters molecular architecture of liver cells. Repairing structure reverses metabolic disease

by Harvard School of Public HealthThe endoplasmic reticulum (ER) is white and lipid droplets appear yellow In this three-dimensional image of the interior of a diseased mouse liver cell created b

Updated on:January 31,2024

Global warming projected to increase health burden from hyponatremia

by Karolinska InstitutetIncidence of hospitalizations due to hyponatremia according to temperature (°C). Credit: Jonatan LindhGlobal warming is likely to increase the number of people requiring h

Updated on: February 19,2024

Global warming projected to increase health burden from hyponatremia

by Karolinska InstitutetIncidence of hospitalizations due to hyponatremia according to temperature (°C). Credit: Jonatan LindhGlobal warming is likely to increase the number of people requiring h

Updated on:February 19,2024

Study reveals how insulin-producing cells work together to respond to metabolic demands

by Emily Packer, George Litchfield,eLifeModulation of individual IPCs by aminergic and peptidergic neurons in patch-clamp recordings. Credit:eLife(2024). DOI: 10.7554/eLife.99548.1Sc

Updated on: September 25,2024

Study reveals how insulin-producing cells work together to respond to metabolic demands

by Emily Packer, George Litchfield,eLifeModulation of individual IPCs by aminergic and peptidergic neurons in patch-clamp recordings. Credit:eLife(2024). DOI: 10.7554/eLife.99548.1Sc

Updated on:September 25,2024

Weight loss linked to improved mood and reduced risk-taking in obese individuals

Weight loss linked to improved mood and reduced risk-taking in obese individualsby Deutsches Zentrum fuer Diabetesforschung DZDCredit: German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE)Peopl

Updated on: July 17,2024

Weight loss linked to improved mood and reduced risk-taking in obese individuals

Weight loss linked to improved mood and reduced risk-taking in obese individualsby Deutsches Zentrum fuer Diabetesforschung DZDCredit: German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE)Peopl

Updated on:July 17,2024

Anti-aging compound improves muscle glucose metabolism in people

by Washington University School of MedicineSenior investigator Samuel Klein, MD, (left), in the laboratory with Adewole Okunade, PhD. Klein's team found that NMN improved the ability of insul

Updated on: February 05,2024

Anti-aging compound improves muscle glucose metabolism in people

by Washington University School of MedicineSenior investigator Samuel Klein, MD, (left), in the laboratory with Adewole Okunade, PhD. Klein's team found that NMN improved the ability of insul

Updated on:February 05,2024

Extracellular vesicles offer new insights into treating endocrine disorders

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainIn a new Scientific Statement released today, the Endocrine Society describes the importance of extracellular vesicles as a new research t

Updated on: February 19,2024

Extracellular vesicles offer new insights into treating endocrine disorders

by The Endocrine SocietyCredit: Pixabay/CC0 Public DomainIn a new Scientific Statement released today, the Endocrine Society describes the importance of extracellular vesicles as a new research t

Updated on:February 19,2024