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Oleic acid: A potential therapy for people with a rare genetic condition

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo
How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also
Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi
Drug found to extend survival in prostate cancer with genetic mutations

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt
Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

FEBRUARY 6, 2024by Camille Bouchard,The ConversationCredit: Unsplash/CC0 Public DomainI have always been fascinated by genetics, a branch of biology that helps explain everything from the striki

Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

FEBRUARY 6, 2024by Camille Bouchard,The ConversationCredit: Unsplash/CC0 Public DomainI have always been fascinated by genetics, a branch of biology that helps explain everything from the striki
Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n
Drug-drug interactions seen in 21.4% of children with medication exposure

Drug-drug interactions seen in 21.4% of children with medication exposure

by Elana GotkineMore than 20% of children with two or more medication exposures experience major drug-drug interactions (DDIs) annually, according to a study published online Jan. 4 inPediatrics

Drug-drug interactions seen in 21.4% of children with medication exposure

by Elana GotkineMore than 20% of children with two or more medication exposures experience major drug-drug interactions (DDIs) annually, according to a study published online Jan. 4 inPediatrics
'Low-intensity' blood stem cell transplants for sickle cell appear safe for lung health

'Low-intensity' blood stem cell transplants for sickle cell appear safe for lung health

byNational Institutes of HealthCredit: National Institutes of HealthSo-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants,

'Low-intensity' blood stem cell transplants for sickle cell appear safe for lung health

byNational Institutes of HealthCredit: National Institutes of HealthSo-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants,
A California panel is holding up studies on psychedelics: Some researchers want it gone

A California panel is holding up studies on psychedelics: Some researchers want it gone

JANUARY 19, 2024by Emily Alpert Reyes, Los Angeles TimesCredit: Pixabay/CC0 Public DomainAt the Pacific Neuroscience Institute in Santa Monica, scientists are eager to explore whether a psychedelic ch

A California panel is holding up studies on psychedelics: Some researchers want it gone

JANUARY 19, 2024by Emily Alpert Reyes, Los Angeles TimesCredit: Pixabay/CC0 Public DomainAt the Pacific Neuroscience Institute in Santa Monica, scientists are eager to explore whether a psychedelic ch
Skeleton-wide study of blood cell formation offers new ways to treat blood cancers, infections

Skeleton-wide study of blood cell formation offers new ways to treat blood cancers, infections

byCincinnati Children's Hospital Medical CenterHow the number of production sites in the sternum can vary significantly by the type of stress on the system, such as blood loss, infection, ca

Skeleton-wide study of blood cell formation offers new ways to treat blood cancers, infections

byCincinnati Children's Hospital Medical CenterHow the number of production sites in the sternum can vary significantly by the type of stress on the system, such as blood loss, infection, ca
Researchers pinpoint issue that could be hampering common chemotherapy drug

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche

Researchers pinpoint issue that could be hampering common chemotherapy drug

by Anika Hazra,University of TorontoGenome-wide CRISPR–Cas9 screens reveal modulators of gemcitabine sensitivity. Credit:Nature Cancer(2024). DOI: 10.1038/s43018-024-00742-zResearche
Simulations reveal mechanism behind protein buildup in Parkinson's disease

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod