CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on: May 30,2024

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on:May 30,2024

Tryptophan in diet and gut bacteria protect against E. coli infection, study shows

by Krishna Ramanujan,Cornell UniversityDietary Trp protects against infection with C. rodentium strain DBS100 in a mouse model of EHEC infection. Credit:Nature(2024). DOI: 10.1038/s4

Updated on: March 20,2024

Tryptophan in diet and gut bacteria protect against E. coli infection, study shows

by Krishna Ramanujan,Cornell UniversityDietary Trp protects against infection with C. rodentium strain DBS100 in a mouse model of EHEC infection. Credit:Nature(2024). DOI: 10.1038/s4

Updated on:March 20,2024

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto

Updated on: March 30,2024

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto

Updated on:March 30,2024

Study reveals insights into diabetic kidney disease and how anti-obesity drugs work

by Monash UniversityThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaData from Australian researchers could partly explain why a trial of a new drug for diabetes, was

Updated on: January 26,2024

Study reveals insights into diabetic kidney disease and how anti-obesity drugs work

by Monash UniversityThis image shows a cross section of a kidney. Credit: Holly Fischer/WikipediaData from Australian researchers could partly explain why a trial of a new drug for diabetes, was

Updated on:January 26,2024

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

Updated on: March 11,2024

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

Updated on:March 11,2024

Research sheds light on effectiveness of FDA's black box warning for asthma drug

by University of OklahomaCredit: Pixabay/CC0 Public DomainA University of Oklahoma study about a "black box warning" for the asthma drug Singulair continues to influence a national conv

Updated on: April 06,2024

Research sheds light on effectiveness of FDA's black box warning for asthma drug

by University of OklahomaCredit: Pixabay/CC0 Public DomainA University of Oklahoma study about a "black box warning" for the asthma drug Singulair continues to influence a national conv

Updated on:April 06,2024

The complex interplay of histone modifications and DNA methylation in epigenetic regulation

Updated on: June 01,2024

The complex interplay of histone modifications and DNA methylation in epigenetic regulation

Updated on:June 01,2024

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on: January 26,2024

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on:January 26,2024

ASH: Daratumumab beneficial for patients with multiple myeloma

by Elana GotkineFor transplantation-eligible patients with newly diagnosed multiple myeloma, the addition of subcutaneous daratumumab combined with bortezomib, lenalidomide, and dexamethasone inductio

Updated on: January 26,2024

ASH: Daratumumab beneficial for patients with multiple myeloma

by Elana GotkineFor transplantation-eligible patients with newly diagnosed multiple myeloma, the addition of subcutaneous daratumumab combined with bortezomib, lenalidomide, and dexamethasone inductio

Updated on:January 26,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on: April 27,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on:April 27,2024

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Updated on: April 06,2024

Researchers present playbook of best practices for cancer team science in the modern era

by Break Through CancerThe Hallmarks of Cancer Collaboration. Based on Hanahan and Weinberg's seminal "Hallmarks of Cancer," this illustration proposes six Hallmarks of Cancer Collaborat

Updated on:April 06,2024

Cloud-magnetic resonance imaging system in the 6G and AI era

by KeAi Communications Co.The workflow of Cloud-MRI system. Credit: Yirong Zhou., et alMagnetic resonance imaging (MRI) has played an important role in modern medical diagnosis, generating petabytes o

Updated on: July 05,2024

Cloud-magnetic resonance imaging system in the 6G and AI era

by KeAi Communications Co.The workflow of Cloud-MRI system. Credit: Yirong Zhou., et alMagnetic resonance imaging (MRI) has played an important role in modern medical diagnosis, generating petabytes o

Updated on:July 05,2024