Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on: March 28,2024

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on:March 28,2024

Combining multiple meds into a single pill reduces cardiovascular deaths, study confirms

by Marley Wiemers,Washington University in St. LouisCredit: Unsplash/CC0 Public DomainTaking a single pill that combines medications targeting cardiovascular disease-related conditions was shown

Updated on: April 06,2024

Combining multiple meds into a single pill reduces cardiovascular deaths, study confirms

by Marley Wiemers,Washington University in St. LouisCredit: Unsplash/CC0 Public DomainTaking a single pill that combines medications targeting cardiovascular disease-related conditions was shown

Updated on:April 06,2024

Higher-dose naloxone spray didn't save more lives, researchers find by Mike Stobbe

by Mike StobbeThis image provided by Hikma Pharmaceuticals shows the company's nasal spray drug Kloxxado, containing 8 milligrams of naloxone. A study published Thursday, Feb. 8, 2024 finds that a

Updated on: March 21,2024

Higher-dose naloxone spray didn't save more lives, researchers find by Mike Stobbe

by Mike StobbeThis image provided by Hikma Pharmaceuticals shows the company's nasal spray drug Kloxxado, containing 8 milligrams of naloxone. A study published Thursday, Feb. 8, 2024 finds that a

Updated on:March 21,2024

New research identifies promising drug combination for multiple myeloma treatment

byRoyal College of Surgeons in IrelandCredit: Unsplash/CC0 Public DomainNew research from the Royal College of Surgeons in Ireland has found that venetoclax, a medication currently approved for

Updated on: March 28,2024

New research identifies promising drug combination for multiple myeloma treatment

byRoyal College of Surgeons in IrelandCredit: Unsplash/CC0 Public DomainNew research from the Royal College of Surgeons in Ireland has found that venetoclax, a medication currently approved for

Updated on:March 28,2024

French territory Guadeloupe declares dengue epidemic

Credit: Unsplash/CC0 Public DomainThe overseas French territory of Guadeloupe declared a dengue epidemic on Thursday, with authorities noting the outbreak was being driven by a less common strain of t

Updated on: December 03,2024

French territory Guadeloupe declares dengue epidemic

Credit: Unsplash/CC0 Public DomainThe overseas French territory of Guadeloupe declared a dengue epidemic on Thursday, with authorities noting the outbreak was being driven by a less common strain of t

Updated on:December 03,2024

A molecular route to decoding synaptic specificity and nerve cell communication

by Tokyo Institute of TechnologyThis study provides insights into the molecular mechanisms underlying the neuronal synaptic interaction. Credit: Tokyo TechNeurons or nerve cells are the fundament

Updated on: April 06,2024

A molecular route to decoding synaptic specificity and nerve cell communication

by Tokyo Institute of TechnologyThis study provides insights into the molecular mechanisms underlying the neuronal synaptic interaction. Credit: Tokyo TechNeurons or nerve cells are the fundament

Updated on:April 06,2024

Understanding Male Infertility: A New AI-Based Approach

This process is often carried out in specialized fertility clinics using microscopes and counting chambers by skilled embryologists.

Updated on: August 05,2024

Understanding Male Infertility: A New AI-Based Approach

This process is often carried out in specialized fertility clinics using microscopes and counting chambers by skilled embryologists.

Updated on:August 05,2024

An aspirin a day? Poll of older adults suggests some who take it may be following outdated advice

by University of MichiganCredit: Pixabay/CC0 Public DomainOne in four older adults take aspirin at least three times a week, mostly in hopes of preventing heart attacks and strokes, a new poll sh

Updated on: March 20,2024

An aspirin a day? Poll of older adults suggests some who take it may be following outdated advice

by University of MichiganCredit: Pixabay/CC0 Public DomainOne in four older adults take aspirin at least three times a week, mostly in hopes of preventing heart attacks and strokes, a new poll sh

Updated on:March 20,2024

Prefrontal Lobotomy in the Treatment of Mental Disorders (GWU, 1942)

Updated on: November 18,2024

Prefrontal Lobotomy in the Treatment of Mental Disorders (GWU, 1942)

Updated on:November 18,2024

Gut Microbiome Changes as Early Indicators of Rheumatoid Arthritis Development

The intricate relationship between the gut microbiome and rheumatoid arthritis (RA) has become a significant area of research, with recent studies providing valuable insights into how gut bacteria might influence the onset and progression of this chronic

Updated on: November 15,2024

Gut Microbiome Changes as Early Indicators of Rheumatoid Arthritis Development

The intricate relationship between the gut microbiome and rheumatoid arthritis (RA) has become a significant area of research, with recent studies providing valuable insights into how gut bacteria might influence the onset and progression of this chronic

Updated on:November 15,2024

Blood test can detect laughing gas and help the police fight whippit abuse

by University of CopenhagenCredit:Forensic Science International(2023). DOI: 10.1016/j.forsciint.2023.111904Forensic blood analysis can reveal whether drivers are high on laughing gas

Updated on: April 28,2024

Blood test can detect laughing gas and help the police fight whippit abuse

by University of CopenhagenCredit:Forensic Science International(2023). DOI: 10.1016/j.forsciint.2023.111904Forensic blood analysis can reveal whether drivers are high on laughing gas

Updated on:April 28,2024

AI Tool Accurately Estimates Gestational Age from Ultrasound

Can novice clinicians accurately estimate gestational age using a low-cost, battery-powered ultrasonography probe with integrated artificial intelligence (AI) image interpretation?

Updated on: August 07,2024

AI Tool Accurately Estimates Gestational Age from Ultrasound

Can novice clinicians accurately estimate gestational age using a low-cost, battery-powered ultrasonography probe with integrated artificial intelligence (AI) image interpretation?

Updated on:August 07,2024