99

Breakthroughs
Sub Categories on Breakthroughs
Latest Articles
Reprogramming tissue mechanically to promote wound healing

Reprogramming tissue mechanically to promote wound healing

by Jan Berndorff,Paul Scherrer InstituteImplanted PR cells show rejuvenation properties in an aged skin model. Credit:Aging Cell(2023). DOI: 10.1111/acel.14032Researchers at PSI and

Reprogramming tissue mechanically to promote wound healing

by Jan Berndorff,Paul Scherrer InstituteImplanted PR cells show rejuvenation properties in an aged skin model. Credit:Aging Cell(2023). DOI: 10.1111/acel.14032Researchers at PSI and
Dual acting drug delivers blood cancer a lethal 'one-two' punch in mice

Dual acting drug delivers blood cancer a lethal 'one-two' punch in mice

byMonash UniversityCredit: Monash UniversityMelbourne researchers have designed a single drug that delivers a lethal "one-two" punch to several types of blood cancer in preclinical stu

Dual acting drug delivers blood cancer a lethal 'one-two' punch in mice

byMonash UniversityCredit: Monash UniversityMelbourne researchers have designed a single drug that delivers a lethal "one-two" punch to several types of blood cancer in preclinical stu
Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind
Spider venom-based heart drug is a step closer

Spider venom-based heart drug is a step closer

JANUARY 17, 2024byUniversity of QueenslandPipette harvesting drop of venom from funnel web spider. Credit: University of QueenslandA spider venom molecule being investigated by a University of Q

Spider venom-based heart drug is a step closer

JANUARY 17, 2024byUniversity of QueenslandPipette harvesting drop of venom from funnel web spider. Credit: University of QueenslandA spider venom molecule being investigated by a University of Q
From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

byJohn Innes CentreCrystal structures of SAP05–SPL5ZnFand SAP05–Rpn10vWAcomplexes revealing the bimodular architecture of SAP05. (A) Cartoon model illustrating the fold of the

From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

byJohn Innes CentreCrystal structures of SAP05–SPL5ZnFand SAP05–Rpn10vWAcomplexes revealing the bimodular architecture of SAP05. (A) Cartoon model illustrating the fold of the
ADHD drug shortages: What to expect if you take Vyvanse and can't access your usual dose

ADHD drug shortages: What to expect if you take Vyvanse and can't access your usual dose

by Alison Poulton,The ConversationCredit: Pixabay/CC0 Public DomainImagine you or your child has attention deficit hyperactivity disorder (ADHD), and after several weeks, or even months, you&#39

ADHD drug shortages: What to expect if you take Vyvanse and can't access your usual dose

by Alison Poulton,The ConversationCredit: Pixabay/CC0 Public DomainImagine you or your child has attention deficit hyperactivity disorder (ADHD), and after several weeks, or even months, you&#39
Advancements in Digital Pathology: The Role of AI and Large Language Models

Advancements in Digital Pathology: The Role of AI and Large Language Models

While the advancements in AI and LLMs hold great promise for the field of digital pathology, it is essential to address the associated challenges and ethical considerations.

Advancements in Digital Pathology: The Role of AI and Large Language Models

While the advancements in AI and LLMs hold great promise for the field of digital pathology, it is essential to address the associated challenges and ethical considerations.
Anti-aging drug rapamycin found to improve immune function through endolysosomes

Anti-aging drug rapamycin found to improve immune function through endolysosomes

by Max Planck SocietyRapamycin is one of the most promising anti-aging substances to date. Rapamycin is named after "Rapa Nui," the local translation for the Easter Islands, where the a

Anti-aging drug rapamycin found to improve immune function through endolysosomes

by Max Planck SocietyRapamycin is one of the most promising anti-aging substances to date. Rapamycin is named after "Rapa Nui," the local translation for the Easter Islands, where the a
Study finds ketamine effects outlast half-life by getting trapped in NMDA receptors

Study finds ketamine effects outlast half-life by getting trapped in NMDA receptors

by Justin Jackson , Medical XpressSingle injection of ketamine no longer causes antidepressant effects on day 3 or day 7. Credit:Nature(2023). DOI: 10.1038/s41586-023-06624-1Researchers at

Study finds ketamine effects outlast half-life by getting trapped in NMDA receptors

by Justin Jackson , Medical XpressSingle injection of ketamine no longer causes antidepressant effects on day 3 or day 7. Credit:Nature(2023). DOI: 10.1038/s41586-023-06624-1Researchers at
'Suspended animation' drug could aid organ transplantation and survival from traumatic injury

'Suspended animation' drug could aid organ transplantation and survival from traumatic injury

by eLifeSNC80 uptake and activity at the delta opioid receptor. a. Distribution of SNC80 in Xenopus tadpoles after 1 and 2 hours of compound exposure. b. Uptake of SNC80 in the tadpole skeletal m

'Suspended animation' drug could aid organ transplantation and survival from traumatic injury

by eLifeSNC80 uptake and activity at the delta opioid receptor. a. Distribution of SNC80 in Xenopus tadpoles after 1 and 2 hours of compound exposure. b. Uptake of SNC80 in the tadpole skeletal m
Inflammation and Cardiovascular Disease: Understanding the Connection

Inflammation and Cardiovascular Disease: Understanding the Connection

While we've known about traditional risk factors like high blood pressure and cholesterol for decades, scientists have recently uncovered another important player in heart health: inflammation.

Inflammation and Cardiovascular Disease: Understanding the Connection

While we've known about traditional risk factors like high blood pressure and cholesterol for decades, scientists have recently uncovered another important player in heart health: inflammation.
Combination therapy found to lower blood pressure in patients receiving ibrutinib

Combination therapy found to lower blood pressure in patients receiving ibrutinib

by American Society of HematologyCredit: Pavel Danilyuk from PexelsCombination treatments with two or more blood pressure drugs can significantly reduce blood pressure in patients taking ibrutini

Combination therapy found to lower blood pressure in patients receiving ibrutinib

by American Society of HematologyCredit: Pavel Danilyuk from PexelsCombination treatments with two or more blood pressure drugs can significantly reduce blood pressure in patients taking ibrutini