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Diabetes drug shows promise against Parkinson's in clinical study

Diabetes drug shows promise against Parkinson's in clinical study

by By Issam Ahmed and Lucie AubourgPeople play table tennis at the Ping Pong Parkinson initiative in Berlin on April 11, 2023, World Parkinson's Day -- the devastating disorder affects 10 million

Diabetes drug shows promise against Parkinson's in clinical study

by By Issam Ahmed and Lucie AubourgPeople play table tennis at the Ping Pong Parkinson initiative in Berlin on April 11, 2023, World Parkinson's Day -- the devastating disorder affects 10 million
Combining genomics and metabolism identifies long-sought mitochondrial choline transporter

Combining genomics and metabolism identifies long-sought mitochondrial choline transporter

byVanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainA multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism

Combining genomics and metabolism identifies long-sought mitochondrial choline transporter

byVanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainA multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism
Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L
Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre
Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

by Vincent Jacobbi,Mayo ClinicCredit: Pixabay/CC0 Public DomainA new Mayo Clinic systematicreview, published in theJournal of Vascular Surgeryhas shed light on genetically inhe

Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

by Vincent Jacobbi,Mayo ClinicCredit: Pixabay/CC0 Public DomainA new Mayo Clinic systematicreview, published in theJournal of Vascular Surgeryhas shed light on genetically inhe
Experimental compound extends life in amyotrophic lateral sclerosis mouse model

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i
Research provides further evidence that epigenetic changes can cause type 2 diabetes

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc
Identifying proteins causally related to COVID-19, healthspan and lifespan

Identifying proteins causally related to COVID-19, healthspan and lifespan

by Impact Journals LLCFlow chart of the study design. Credit:Aging(2024). DOI: 10.18632/aging.205711A new research paper titled "Using genetics and proteomics data to identify protein

Identifying proteins causally related to COVID-19, healthspan and lifespan

by Impact Journals LLCFlow chart of the study design. Credit:Aging(2024). DOI: 10.18632/aging.205711A new research paper titled "Using genetics and proteomics data to identify protein
New study shows a role for cholesterol in pain perception

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell
Long COVID may harm cognition

Long COVID may harm cognition

MARCH 3, 2024by Robin FosterIn a finding that unearths yet another way Long COVID can harm health, new research finds the condition may trigger thinking declines.Published Thursday in theNew Eng

Long COVID may harm cognition

MARCH 3, 2024by Robin FosterIn a finding that unearths yet another way Long COVID can harm health, new research finds the condition may trigger thinking declines.Published Thursday in theNew Eng
Scientists explore the coupling between health span and lifespan in Caenorhabditis

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between
Sex-specific blood biomarkers linked to memory changes in middle-aged adults: The Framingham heart study

Sex-specific blood biomarkers linked to memory changes in middle-aged adults: The Framingham heart study

by Boston University School of MedicineCasual dose-response curves of FBG, HDL, and adiponectin with annualized memory change. The x-axis represents the values of biomarkers. The y-axis represent

Sex-specific blood biomarkers linked to memory changes in middle-aged adults: The Framingham heart study

by Boston University School of MedicineCasual dose-response curves of FBG, HDL, and adiponectin with annualized memory change. The x-axis represents the values of biomarkers. The y-axis represent