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Breakthroughs
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Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec
The Human Tumor Atlas Network: Mapping Cancer's Complexity and Evolution

The Human Tumor Atlas Network: Mapping Cancer's Complexity and Evolution

The Human Tumor Atlas Network (HTAN) stands at the forefront of cancer research, representing a groundbreaking initiative funded by the National Cancer Institute (NCI) as part of the ambitious Cancer Moonshot℠ program. Launched in 2018, HTAN's primary mis

The Human Tumor Atlas Network: Mapping Cancer's Complexity and Evolution

The Human Tumor Atlas Network (HTAN) stands at the forefront of cancer research, representing a groundbreaking initiative funded by the National Cancer Institute (NCI) as part of the ambitious Cancer Moonshot℠ program. Launched in 2018, HTAN's primary mis
From lab to legislation: How research shapes health policies in Latin America

From lab to legislation: How research shapes health policies in Latin America

by TranSpreadCredit: Unsplash/CC0 Public DomainHealth literacy and education are pivotal for shaping effective health policies, yet the integration of research findings into policy-making processes re

From lab to legislation: How research shapes health policies in Latin America

by TranSpreadCredit: Unsplash/CC0 Public DomainHealth literacy and education are pivotal for shaping effective health policies, yet the integration of research findings into policy-making processes re
Case study: Drug-resistant bacteria responds to phage-antibiotic combo therapy

Case study: Drug-resistant bacteria responds to phage-antibiotic combo therapy

FEBRUARY 14, 2024 Editors' notesbyUniversity of PittsburghCredit: CC0 Public DomainIt was a last-ditch effort. For years doctors had tried to keep a patient's recurrent drug-resistant ba

Case study: Drug-resistant bacteria responds to phage-antibiotic combo therapy

FEBRUARY 14, 2024 Editors' notesbyUniversity of PittsburghCredit: CC0 Public DomainIt was a last-ditch effort. For years doctors had tried to keep a patient's recurrent drug-resistant ba
Long COVID may harm cognition

Long COVID may harm cognition

MARCH 3, 2024by Robin FosterIn a finding that unearths yet another way Long COVID can harm health, new research finds the condition may trigger thinking declines.Published Thursday in theNew Eng

Long COVID may harm cognition

MARCH 3, 2024by Robin FosterIn a finding that unearths yet another way Long COVID can harm health, new research finds the condition may trigger thinking declines.Published Thursday in theNew Eng
Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com
New recommendations make it easier for patients to give feedback on their health

New recommendations make it easier for patients to give feedback on their health

FEBRUARY 29, 2024byUniversity of BirminghamCredit: CC0 Public DomainPatients providing feedback on their health during research or in clinical practice could now find it less onerous, thanks to

New recommendations make it easier for patients to give feedback on their health

FEBRUARY 29, 2024byUniversity of BirminghamCredit: CC0 Public DomainPatients providing feedback on their health during research or in clinical practice could now find it less onerous, thanks to
Enhancing hypoxia-activated prodrug anticancer therapy

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres
Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there
Experimental compound extends life in amyotrophic lateral sclerosis mouse model

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i

Experimental compound extends life in amyotrophic lateral sclerosis mouse model

FEBRUARY 6, 2024byUT Southwestern Medical CenterMAP4K interactome and the effect on RANGAP1 subcellular distribution.AWestern-blotting analysis of proteins after proximity labeling i