Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on: March 28,2024

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on:March 28,2024

A brief history of drug-fueled combatants

by Colin Davidson,The ConversationA chess piece depicting a berserker biting his shield. Credit:National Museums Scotland/Wikimedia Commons,CC BY-SAMy friend Luke used to drink a pin

Updated on: January 26,2024

A brief history of drug-fueled combatants

by Colin Davidson,The ConversationA chess piece depicting a berserker biting his shield. Credit:National Museums Scotland/Wikimedia Commons,CC BY-SAMy friend Luke used to drink a pin

Updated on:January 26,2024

Beating back bitter taste in medicine: Scientists discover that diabetes drug is partially effective as a bitter blocker

by Karen Kreeger,Monell Chemical Senses CenterCredit: CC0 Public DomainThe bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are part

Updated on: April 28,2024

Beating back bitter taste in medicine: Scientists discover that diabetes drug is partially effective as a bitter blocker

by Karen Kreeger,Monell Chemical Senses CenterCredit: CC0 Public DomainThe bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are part

Updated on:April 28,2024

Biosimilar biologics do not always reduce out-of-pocket costs

by Lori SolomonBiosimilar competition is not consistently associated with lower out-of-pocket (OOP) costs for commercially insured outpatients, according to a study published online March 29 inJ

Updated on: April 06,2024

Biosimilar biologics do not always reduce out-of-pocket costs

by Lori SolomonBiosimilar competition is not consistently associated with lower out-of-pocket (OOP) costs for commercially insured outpatients, according to a study published online March 29 inJ

Updated on:April 06,2024

Health care database analysis highlights lingering symptoms long after COVID-19 infection

byUniversity of OxfordIncidence rate of post-acute COVID-19 symptoms in the infected cohort. Note: Plots have been scaled independently so that all incidences can be visualized. Credit:eCl

Updated on: December 04,2024

Health care database analysis highlights lingering symptoms long after COVID-19 infection

byUniversity of OxfordIncidence rate of post-acute COVID-19 symptoms in the infected cohort. Note: Plots have been scaled independently so that all incidences can be visualized. Credit:eCl

Updated on:December 04,2024

Prefrontal Lobotomy in the Treatment of Mental Disorders (GWU, 1942)

Updated on: November 18,2024

Prefrontal Lobotomy in the Treatment of Mental Disorders (GWU, 1942)

Updated on:November 18,2024

Many drugs are prescribed for conditions they weren't tested for—here's what you need to know

by Dipa Kamdar,The ConversationCredit: Pixabay/CC0 Public DomainAll prescription drugs need a license from a regulator to treat a specific condition. But licensed drugs can be prescribed for con

Updated on: March 30,2024

Many drugs are prescribed for conditions they weren't tested for—here's what you need to know

by Dipa Kamdar,The ConversationCredit: Pixabay/CC0 Public DomainAll prescription drugs need a license from a regulator to treat a specific condition. But licensed drugs can be prescribed for con

Updated on:March 30,2024

Anxiety drug pregabalin is linked to a rising number of deaths. Here's what you should know

by Ian Hamilton and Harry Sumnall,The ConversationCredit: Pixabay/CC0 Public DomainThere has been a significant rise in deaths linked to the commonly prescribed anxiety drug, pregabalin. While i

Updated on: March 20,2024

Anxiety drug pregabalin is linked to a rising number of deaths. Here's what you should know

by Ian Hamilton and Harry Sumnall,The ConversationCredit: Pixabay/CC0 Public DomainThere has been a significant rise in deaths linked to the commonly prescribed anxiety drug, pregabalin. While i

Updated on:March 20,2024

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats

Updated on: December 30,2023

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats

Updated on:December 30,2023

Adversity's Imprint: How Hardship Shapes the Brain

Updated on: July 12,2024

Adversity's Imprint: How Hardship Shapes the Brain

Updated on:July 12,2024

Researchers create genetic atlas detailing early stages of zebrafish development

byNIH/Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentZebrafish are model organisms for studying early development. Credit: J. Swan and K. Tabor, NICHD/NIHResearch

Updated on: December 30,2023

Researchers create genetic atlas detailing early stages of zebrafish development

byNIH/Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentZebrafish are model organisms for studying early development. Credit: J. Swan and K. Tabor, NICHD/NIHResearch

Updated on:December 30,2023

AI's Breakthroughs in Ovarian Cancer Diagnosis and Treatment

Updated on: June 12,2024

AI's Breakthroughs in Ovarian Cancer Diagnosis and Treatment

Updated on:June 12,2024