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Breakthroughs
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New combination therapy found effective against drug-sensitive and resistant tick-borne babesiosis

New combination therapy found effective against drug-sensitive and resistant tick-borne babesiosis

by Isabella Backman,Yale UniversityThe lab of Choukri Ben Mamoun, PhD (left), has a long-standing interest in fighting this tick-borne disease. Credit: Yale UniversityDrug-resistant babesiosis m

New combination therapy found effective against drug-sensitive and resistant tick-borne babesiosis

by Isabella Backman,Yale UniversityThe lab of Choukri Ben Mamoun, PhD (left), has a long-standing interest in fighting this tick-borne disease. Credit: Yale UniversityDrug-resistant babesiosis m
Durvalumab and Tremelimumab before surgery in patients with HR+/HER2-negative breast cancer

Durvalumab and Tremelimumab before surgery in patients with HR+/HER2-negative breast cancer

by Impact Journals LLCAnalysis of immune cell subsets during neoadjuvant therapy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28567A new research paper was published inOncotarg

Durvalumab and Tremelimumab before surgery in patients with HR+/HER2-negative breast cancer

by Impact Journals LLCAnalysis of immune cell subsets during neoadjuvant therapy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28567A new research paper was published inOncotarg
Mutation mapping shows errors in protein location are a common cause of disease

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of
Popular blood thinner associated with higher risk of bleeding complications

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu
Diabetes and weight-loss drugs—Ozempic and Wegovy—not associated with increased suicidal thoughts, finds study

Diabetes and weight-loss drugs—Ozempic and Wegovy—not associated with increased suicidal thoughts, finds study

byCase Western Reserve UniversityCredit: Unsplash/CC0 Public DomainA new study by researchers at the Case Western Reserve School of Medicine reveals that a chemical used in the diabetes drug Oze

Diabetes and weight-loss drugs—Ozempic and Wegovy—not associated with increased suicidal thoughts, finds study

byCase Western Reserve UniversityCredit: Unsplash/CC0 Public DomainA new study by researchers at the Case Western Reserve School of Medicine reveals that a chemical used in the diabetes drug Oze
New cell model reveals how hepatitis E viruses affect nerve cells

New cell model reveals how hepatitis E viruses affect nerve cells

by Meike Drießen,Ruhr-Universitaet-BochumCredit: Ruhr-Universitaet-BochumHepatitis E viruses (HEV) typically cause liver infections. They can, however, also infect other organs and cause neurolo

New cell model reveals how hepatitis E viruses affect nerve cells

by Meike Drießen,Ruhr-Universitaet-BochumCredit: Ruhr-Universitaet-BochumHepatitis E viruses (HEV) typically cause liver infections. They can, however, also infect other organs and cause neurolo
Scientists discover a framework in the brain for organizing the order of things

Scientists discover a framework in the brain for organizing the order of things

byNorwegian University of Science and TechnologyUltraslow oscillations in MEC neurons.a, Neural activity was recorded through a prism from GCaMP6m-expressing neurons of the MEC in head-fix

Scientists discover a framework in the brain for organizing the order of things

byNorwegian University of Science and TechnologyUltraslow oscillations in MEC neurons.a, Neural activity was recorded through a prism from GCaMP6m-expressing neurons of the MEC in head-fix
Researchers work to preserve fertility for people undergoing gene therapy

Researchers work to preserve fertility for people undergoing gene therapy

byNational Institutes of HealthCD117-ADC depletes both human and non-human primate CD34+ cells.AEscalating doses of CD117-ADC were added to primary human and rhesus CD34+ cells in cu

Researchers work to preserve fertility for people undergoing gene therapy

byNational Institutes of HealthCD117-ADC depletes both human and non-human primate CD34+ cells.AEscalating doses of CD117-ADC were added to primary human and rhesus CD34+ cells in cu
Follow-up finds landmark steroid study remains safe 50 years on

Follow-up finds landmark steroid study remains safe 50 years on

byUniversity of AucklandCredit: Bruno Abdiel from PexelsA study has found there are no adverse long-term cardiovascular health consequences for the now-adult children of mothers who were given c

Follow-up finds landmark steroid study remains safe 50 years on

byUniversity of AucklandCredit: Bruno Abdiel from PexelsA study has found there are no adverse long-term cardiovascular health consequences for the now-adult children of mothers who were given c
Novel compound AC102 restores hearing in preclinical models of sudden hearing loss

Novel compound AC102 restores hearing in preclinical models of sudden hearing loss

by AudioCure Pharma GmbHThe effect of AC102 on OHC survival after noise exposure in vivo. (A) Schematic of OHCs and IHCs within the cochlea. (B) Quantification of OHCs 14 d after noise exposure reveal

Novel compound AC102 restores hearing in preclinical models of sudden hearing loss

by AudioCure Pharma GmbHThe effect of AC102 on OHC survival after noise exposure in vivo. (A) Schematic of OHCs and IHCs within the cochlea. (B) Quantification of OHCs 14 d after noise exposure reveal
Researchers identify brain center responsible for responses to rapid temperature change

Researchers identify brain center responsible for responses to rapid temperature change

by Win Reynolds,Northwestern UniversityTPN-IIIs display ON responses to temperature change. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42864-5We've all heard it:

Researchers identify brain center responsible for responses to rapid temperature change

by Win Reynolds,Northwestern UniversityTPN-IIIs display ON responses to temperature change. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42864-5We've all heard it:
Psilocybin found to reduce chronic pain in rats

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats