Research sheds light on effectiveness of FDA's black box warning for asthma drug

by University of OklahomaCredit: Pixabay/CC0 Public DomainA University of Oklahoma study about a "black box warning" for the asthma drug Singulair continues to influence a national conv

Updated on: April 06,2024

Research sheds light on effectiveness of FDA's black box warning for asthma drug

by University of OklahomaCredit: Pixabay/CC0 Public DomainA University of Oklahoma study about a "black box warning" for the asthma drug Singulair continues to influence a national conv

Updated on:April 06,2024

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on: April 28,2024

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on:April 28,2024

A new weapon against the super-tough C diff bacteria tested in phase-one human trial

by Laurie Fickman,University of HoustonFecal drug concentrations of omadacycline and vancomycin. Credit:The Journal of Infectious Diseases(2023). DOI: 10.1093/infdis/jiad537In a phas

Updated on: December 30,2023

A new weapon against the super-tough C diff bacteria tested in phase-one human trial

by Laurie Fickman,University of HoustonFecal drug concentrations of omadacycline and vancomycin. Credit:The Journal of Infectious Diseases(2023). DOI: 10.1093/infdis/jiad537In a phas

Updated on:December 30,2023

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on: January 26,2024

Epilepsy drug shows promise in slowing joint degeneration in osteoarthritis

by Yale Universitya, Safranin O and Fast Green-stained sections of knee joints of mice with the indicated genotype (n = 8). Scale bar, 50 µm.b–e, OARSI score (b), osteophyte development (c)

Updated on:January 26,2024

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng

Updated on: April 02,2024

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng

Updated on:April 02,2024

Poor trial results may prompt maker to pull ALS drug from market

by Robin FosterFollowing disappointing trial results, the maker of a controversial ALS drug may pull the medication off the market.In astatementissued Friday, Amylyx Pharmaceuticals said t

Updated on: March 20,2024

Poor trial results may prompt maker to pull ALS drug from market

by Robin FosterFollowing disappointing trial results, the maker of a controversial ALS drug may pull the medication off the market.In astatementissued Friday, Amylyx Pharmaceuticals said t

Updated on:March 20,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on: April 27,2024

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on:April 27,2024

FDA looking into new risks with popular weight-loss drugs

by Robin FosterThe U.S. Food and Drug Administration is investigating reports of additional dangers linked to several wildly popular weight-loss drugs.In aquarterly reportissued this week,

Updated on: January 26,2024

FDA looking into new risks with popular weight-loss drugs

by Robin FosterThe U.S. Food and Drug Administration is investigating reports of additional dangers linked to several wildly popular weight-loss drugs.In aquarterly reportissued this week,

Updated on:January 26,2024

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Updated on: January 02,2024

Unlocking the human genome: Innovative machine learning tool predicts functional consequences of genetic variants

byThe Mount Sinai HospitalLoGoFunc identifies harmful (left) and harmless (right) genetic variations in the Vasopressin V2 receptor protein using a structure predicted by AlphaFold2. This helps

Updated on:January 02,2024

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on: March 28,2024

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on:March 28,2024

Wastewater sequencing reveals community and variant dynamics of the collective human virome

by Ana María S. Rodríguez,Baylor College of MedicineStudy sites, capture, and viral diversity. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42064-1In the not-so-distan

Updated on: December 28,2023

Wastewater sequencing reveals community and variant dynamics of the collective human virome

by Ana María S. Rodríguez,Baylor College of MedicineStudy sites, capture, and viral diversity. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-42064-1In the not-so-distan

Updated on:December 28,2023

Reframing cerebral palsy as a lifelong physical disability could improve adult care, researchers say

by Valerie Goodwin,University of MichiganA boy is supported by his family and care team as a child but feels left with questions as an adult. Credit: Justine Ross, Michigan MedicineIn the United

Updated on: December 03,2024

Reframing cerebral palsy as a lifelong physical disability could improve adult care, researchers say

by Valerie Goodwin,University of MichiganA boy is supported by his family and care team as a child but feels left with questions as an adult. Credit: Justine Ross, Michigan MedicineIn the United

Updated on:December 03,2024