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Breakthroughs
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How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also
Biological engineers discover why a promising drug failed in clinical trials

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima
Scientists harness ultrasound for drug delivery and tissue implantation

Scientists harness ultrasound for drug delivery and tissue implantation

by Technion - Israel Institute of TechnologyUltrasound mediated polymerization of acousto-sensitive biomaterials. Credit: Small Methods (2024). DOI: 10.1002/smtd.202301197Research presents an advance

Scientists harness ultrasound for drug delivery and tissue implantation

by Technion - Israel Institute of TechnologyUltrasound mediated polymerization of acousto-sensitive biomaterials. Credit: Small Methods (2024). DOI: 10.1002/smtd.202301197Research presents an advance
Oleic acid: A potential therapy for people with a rare genetic condition

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo
Using deep learning techniques to improve liver disease diagnosis and treatment

Using deep learning techniques to improve liver disease diagnosis and treatment

byGeorgia Institute of TechnologyComparison of the workflow between the proposed deep learning-based image quality classification and the traditional visual inspection. Credit:Journal of M

Using deep learning techniques to improve liver disease diagnosis and treatment

byGeorgia Institute of TechnologyComparison of the workflow between the proposed deep learning-based image quality classification and the traditional visual inspection. Credit:Journal of M
Amid record year for dengue infections, study finds climate change responsible for 19% of rising dengue burden

Amid record year for dengue infections, study finds climate change responsible for 19% of rising dengue burden

by American Society of Tropical Medicine & HygieneCredit: CC0 Public DomainClimate change is having a massive global impact on dengue transmission, accounting for 19% of the current dengue burden,

Amid record year for dengue infections, study finds climate change responsible for 19% of rising dengue burden

by American Society of Tropical Medicine & HygieneCredit: CC0 Public DomainClimate change is having a massive global impact on dengue transmission, accounting for 19% of the current dengue burden,
Color-adjusting technique for histopathology image datasets could help empower machine-learning-based diagnostic tools

Color-adjusting technique for histopathology image datasets could help empower machine-learning-based diagnostic tools

bySPIETissue image datasets processed by stained SAN (bottom row) achieve color distributions that are more consistent than those processed using other techniques. Such consistency is essential

Color-adjusting technique for histopathology image datasets could help empower machine-learning-based diagnostic tools

bySPIETissue image datasets processed by stained SAN (bottom row) achieve color distributions that are more consistent than those processed using other techniques. Such consistency is essential
New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo

New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo
Study of usefulness of lockdowns during epidemics identifies alternate solution

Study of usefulness of lockdowns during epidemics identifies alternate solution

FEBRUARY 21, 2024by Caitlin Kizielewicz,Carnegie Mellon University's Heinz CollegeFlow diagram of the epidemiological model. Compartments are illustrated with boxes, while the other state va

Study of usefulness of lockdowns during epidemics identifies alternate solution

FEBRUARY 21, 2024by Caitlin Kizielewicz,Carnegie Mellon University's Heinz CollegeFlow diagram of the epidemiological model. Compartments are illustrated with boxes, while the other state va
Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

by Impact Journals LLCGene expression profiling revealed various patterns of changes in PFC and hippocampus of P301S mice at different ages. Credit:Aging(2023). DOI: 10.18632/aging.205057A

Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

by Impact Journals LLCGene expression profiling revealed various patterns of changes in PFC and hippocampus of P301S mice at different ages. Credit:Aging(2023). DOI: 10.18632/aging.205057A
First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average

First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average
New wearable patch measures trace perspiration during activity and rest

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear