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Breakthroughs
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How to make mRNA therapeutics safe from the start

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern
Researchers make mice a more powerful tool to study a wide range of human diseases

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce
Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainA recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic

Clinical presentation of IDDMSSD syndrome likely associated with molecular location of mutation in PAK1 gene

by Texas Children's HospitalCredit: Pixabay/CC0 Public DomainA recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic
Clinical trial: New dual therapy could revolutionize treatment of urothelial and bladder cancers

Clinical trial: New dual therapy could revolutionize treatment of urothelial and bladder cancers

by Georgia Gowing,Macquarie UniversityDr. Alison Zhang. Credit: Macquarie UniversityAn international clinical trial of a treatment for advanced urothelial cancer has found a new dual therapy can

Clinical trial: New dual therapy could revolutionize treatment of urothelial and bladder cancers

by Georgia Gowing,Macquarie UniversityDr. Alison Zhang. Credit: Macquarie UniversityAn international clinical trial of a treatment for advanced urothelial cancer has found a new dual therapy can
Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease
Off-label use of a common antibiotic to treat muscular dystrophy

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads
Meningitis may have a much greater impact on child mortality than previously thought

Meningitis may have a much greater impact on child mortality than previously thought

byBarcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainMeningitis contributes to higher child mortality rates than estimated by the WHO, according to a new study by the CHAMPS n

Meningitis may have a much greater impact on child mortality than previously thought

byBarcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainMeningitis contributes to higher child mortality rates than estimated by the WHO, according to a new study by the CHAMPS n
Male infertility genetic study improves molecular diagnostics and personalized management of patients

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these
Study highlights impact of aldehydes on DNA damage and aging

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi
Scientists harness ultrasound for drug delivery and tissue implantation

Scientists harness ultrasound for drug delivery and tissue implantation

by Technion - Israel Institute of TechnologyUltrasound mediated polymerization of acousto-sensitive biomaterials. Credit: Small Methods (2024). DOI: 10.1002/smtd.202301197Research presents an advance

Scientists harness ultrasound for drug delivery and tissue implantation

by Technion - Israel Institute of TechnologyUltrasound mediated polymerization of acousto-sensitive biomaterials. Credit: Small Methods (2024). DOI: 10.1002/smtd.202301197Research presents an advance
CBD products don't ease pain and are potentially harmful, study finds

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm
Research may offer relief to migraine sufferers

Research may offer relief to migraine sufferers

FEBRUARY 21, 2024by Josh Barney,University of VirginiaRoughly one in five women suffer from migraines, compared to fewer than one in 10 men. Credit: John DiJulia, University CommunicationsResear

Research may offer relief to migraine sufferers

FEBRUARY 21, 2024by Josh Barney,University of VirginiaRoughly one in five women suffer from migraines, compared to fewer than one in 10 men. Credit: John DiJulia, University CommunicationsResear