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Researchers turn the body's B cells into tiny surveillance machines, antibody factories

Researchers turn the body's B cells into tiny surveillance machines, antibody factories

by Leigh Hopper,University of Southern CaliforniaGenome editing at the constant region of the IgH locus. a, Antibody H chains are encoded by a rearranged variable domain (VH) spliced to a consta
Updated on: July 30,2024
Researchers turn the body's B cells into tiny surveillance machines, antibody factories

Researchers turn the body's B cells into tiny surveillance machines, antibody factories

by Leigh Hopper,University of Southern CaliforniaGenome editing at the constant region of the IgH locus. a, Antibody H chains are encoded by a rearranged variable domain (VH) spliced to a consta
Updated on:July 30,2024
Kidney patients' lives could be saved by international change to donor policies

Kidney patients' lives could be saved by international change to donor policies

byNewcastle UniversityCredit: Pixabay/CC0 Public DomainThousands of kidney disease patients' lives could be saved around the world each year if countries adopted the UK's rules on organ
Updated on: December 03,2024
Kidney patients' lives could be saved by international change to donor policies

Kidney patients' lives could be saved by international change to donor policies

byNewcastle UniversityCredit: Pixabay/CC0 Public DomainThousands of kidney disease patients' lives could be saved around the world each year if countries adopted the UK's rules on organ
Updated on:December 03,2024
Therapeutic approach to treat virus-induced lung failure for severe COVID-19 shows promise in clinical trial

Therapeutic approach to treat virus-induced lung failure for severe COVID-19 shows promise in clinical trial

byUniversity of CologneKaplan–Meier cumulative rate and its 95% confidence interval for the time to clinical improvement. SOC, standard of care. Credit:eClinicalMedicine(2024). DOI:
Updated on: December 03,2024
Therapeutic approach to treat virus-induced lung failure for severe COVID-19 shows promise in clinical trial

Therapeutic approach to treat virus-induced lung failure for severe COVID-19 shows promise in clinical trial

byUniversity of CologneKaplan–Meier cumulative rate and its 95% confidence interval for the time to clinical improvement. SOC, standard of care. Credit:eClinicalMedicine(2024). DOI:
Updated on:December 03,2024
Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n
Updated on: April 28,2024
Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n
Updated on:April 28,2024
Embryo's signaling mechanism may promote healthy aging, combat neurodegenerative diseases

Embryo's signaling mechanism may promote healthy aging, combat neurodegenerative diseases

by Melissa Rohman,Northwestern UniversityNHR-49 is important in multiple paradigms of stress resilience. (A) Heat stress survival of wild type and daf-2(e1370) mutants crossed into nhr-49(nr2041
Updated on: July 08,2024
Embryo's signaling mechanism may promote healthy aging, combat neurodegenerative diseases

Embryo's signaling mechanism may promote healthy aging, combat neurodegenerative diseases

by Melissa Rohman,Northwestern UniversityNHR-49 is important in multiple paradigms of stress resilience. (A) Heat stress survival of wild type and daf-2(e1370) mutants crossed into nhr-49(nr2041
Updated on:July 08,2024
Researchers find unexpected connection between SARS-CoV-2 and fragile X syndrome

Researchers find unexpected connection between SARS-CoV-2 and fragile X syndrome

FEBRUARY 27, 2024byUniversity of CopenhagenCredit: CC0 Public DomainHow does coronavirus spread through the body? A new study,availableon the preprint serverbioRxiv, can help u
Updated on: March 28,2024
Researchers find unexpected connection between SARS-CoV-2 and fragile X syndrome

Researchers find unexpected connection between SARS-CoV-2 and fragile X syndrome

FEBRUARY 27, 2024byUniversity of CopenhagenCredit: CC0 Public DomainHow does coronavirus spread through the body? A new study,availableon the preprint serverbioRxiv, can help u
Updated on:March 28,2024
Combining epigenetic cancer medications may have benefit for colorectal cancers and other tumor types

Combining epigenetic cancer medications may have benefit for colorectal cancers and other tumor types

by Van Andel Research InstituteCredit: Unsplash/CC0 Public DomainA pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers
Updated on: March 30,2024
Combining epigenetic cancer medications may have benefit for colorectal cancers and other tumor types

Combining epigenetic cancer medications may have benefit for colorectal cancers and other tumor types

by Van Andel Research InstituteCredit: Unsplash/CC0 Public DomainA pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers
Updated on:March 30,2024
Study shows tendency for infection and bacterial flora explain caries

Study shows tendency for infection and bacterial flora explain caries

byUmea UniversityCredit:eBioMedicine(2024). DOI: 10.1016/j.ebiom.2024.105001Researchers at Umeå University have for the first time been able to show that individual variation in susc
Updated on: March 13,2024
Study shows tendency for infection and bacterial flora explain caries

Study shows tendency for infection and bacterial flora explain caries

byUmea UniversityCredit:eBioMedicine(2024). DOI: 10.1016/j.ebiom.2024.105001Researchers at Umeå University have for the first time been able to show that individual variation in susc
Updated on:March 13,2024
Gene editing precisely repairs immune cells

Gene editing precisely repairs immune cells

byMax Delbrück Center for Molecular MedicineMutated T cells are unable to kill B cells (red) induced by the Epstein-Barr virus. This causes other immune cells to flow into the area of infection,
Updated on: March 13,2024
Gene editing precisely repairs immune cells

Gene editing precisely repairs immune cells

byMax Delbrück Center for Molecular MedicineMutated T cells are unable to kill B cells (red) induced by the Epstein-Barr virus. This causes other immune cells to flow into the area of infection,
Updated on:March 13,2024
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