FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on: August 12,2024

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on:August 12,2024

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Updated on: March 13,2024

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Updated on:March 13,2024

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti

Updated on: March 27,2024

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti

Updated on:March 27,2024

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Updated on: March 14,2024

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Updated on:March 14,2024

UK issues guidelines for use of stem cell-based embryo models in research

byUniversity of CambridgeThese models can be created in the lab and mimic aspects of early human embryo development, which raises various ethical considerations. Credit: Irene Zorzan and Teresa

Updated on: July 05,2024

UK issues guidelines for use of stem cell-based embryo models in research

byUniversity of CambridgeThese models can be created in the lab and mimic aspects of early human embryo development, which raises various ethical considerations. Credit: Irene Zorzan and Teresa

Updated on:July 05,2024

Better cancer trials could be around the corner

by Cold Spring Harbor LaboratoryCredit: Pixabay/CC0 Public DomainCold Spring Harbor Laboratory Associate Professor and Cancer Center member Tobias Janowitz led aCOVID-19 clinical trial&nbsp

Updated on: March 30,2024

Better cancer trials could be around the corner

by Cold Spring Harbor LaboratoryCredit: Pixabay/CC0 Public DomainCold Spring Harbor Laboratory Associate Professor and Cancer Center member Tobias Janowitz led aCOVID-19 clinical trial&nbsp

Updated on:March 30,2024

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Updated on: March 15,2024

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Updated on:March 15,2024

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death

Updated on: March 14,2024

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death

Updated on:March 14,2024

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i

Updated on: March 15,2024

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i

Updated on:March 15,2024

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on: April 28,2024

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on:April 28,2024

Review paper unveils the potential of suppressor tRNA in gene therapy

byScience China PressCredit: Science China PressA review article provides a comprehensive overview of the biological mechanisms of suppressor tRNA, traces the development history of related rese

Updated on: July 09,2024

Review paper unveils the potential of suppressor tRNA in gene therapy

byScience China PressCredit: Science China PressA review article provides a comprehensive overview of the biological mechanisms of suppressor tRNA, traces the development history of related rese

Updated on:July 09,2024

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A

Updated on: March 30,2024

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A

Updated on:March 30,2024