Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o

Updated on: March 14,2024

Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o

Updated on:March 14,2024

Critical Review of the Mechanisms by Which Tumor-Derived Exosomes Induce Immunosuppressive Macrophages through Metabolic Reprogramming

Updated on: September 13,2024

Critical Review of the Mechanisms by Which Tumor-Derived Exosomes Induce Immunosuppressive Macrophages through Metabolic Reprogramming

Updated on:September 13,2024

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on: March 13,2024

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on:March 13,2024

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

Updated on: March 13,2024

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

Updated on:March 13,2024

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti

Updated on: March 27,2024

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti

Updated on:March 27,2024

The First CRISPR Gene Therapy Is Here

Updated on: September 02,2024

The First CRISPR Gene Therapy Is Here

Updated on:September 02,2024

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Updated on: July 17,2024

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Updated on:July 17,2024

Engineered platelets can induce anti-inflammatory, immunosuppressive response, finds scientist

by Marlene Leung,St. Michael's HospitalCredit: Pixabay/CC0 Public DomainNew research led by a St. Michael's Hospital scientist reveals how platelets can inhibit inflammation and immune r

Updated on: January 27,2024

Engineered platelets can induce anti-inflammatory, immunosuppressive response, finds scientist

by Marlene Leung,St. Michael's HospitalCredit: Pixabay/CC0 Public DomainNew research led by a St. Michael's Hospital scientist reveals how platelets can inhibit inflammation and immune r

Updated on:January 27,2024

Ehrapy: A new open-source tool for analyzing complex health data

byHelmholtz Association of German Research CentresLogo ehrapy. Credit: Meshal AnsariLed by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for t

Updated on: September 13,2024

Ehrapy: A new open-source tool for analyzing complex health data

byHelmholtz Association of German Research CentresLogo ehrapy. Credit: Meshal AnsariLed by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for t

Updated on:September 13,2024

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i

Updated on: March 15,2024

Bridging diet, microbes, and metabolism: Implications for metabolic disorders

FEBRUARY 20, 2024byBoyce Thompson InstituteTransgenic animals expressing a green fluorescent protein attached to the fatty acid desaturase, FAT-7. Green color represents the induction of FAT-7 i

Updated on:March 15,2024

Rapid drug test to provide patients with better care

byWalter and Eliza Hall Institute of Medical ResearchMass spectroscopy chromatogram: (a) patient plasma with enzalutamide peak with extracted ion chromatogram adduct (465 m/z); (b) in the same p

Updated on: July 06,2024

Rapid drug test to provide patients with better care

byWalter and Eliza Hall Institute of Medical ResearchMass spectroscopy chromatogram: (a) patient plasma with enzalutamide peak with extracted ion chromatogram adduct (465 m/z); (b) in the same p

Updated on:July 06,2024

Researchers discover a potential cause of Parkinson's disease

MAY 5, 2023byUniversity of HelsinkiAggregation of alpha-synuclein in a nerve cell. Credit: Timo Myöhänen research groupThere are currently 8 million patients with Parkinson's disease in the

Updated on: March 28,2024

Researchers discover a potential cause of Parkinson's disease

MAY 5, 2023byUniversity of HelsinkiAggregation of alpha-synuclein in a nerve cell. Credit: Timo Myöhänen research groupThere are currently 8 million patients with Parkinson's disease in the

Updated on:March 28,2024