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The dual role of well-known protein sheds light on Parkinson's disease mechanisms

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th
New resource maps gene-disease links across common conditions, paving the way for personalized medicine

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov
How aging affects stem cells: A fly's tale

How aging affects stem cells: A fly's tale

byRIKENExcessive cell proliferation (left) and stem cell exhaustion (right) during aging. Credit: RIKENScientists from the RIKEN Center for Biosystems Dynamics Research (BDR) have identified key

How aging affects stem cells: A fly's tale

byRIKENExcessive cell proliferation (left) and stem cell exhaustion (right) during aging. Credit: RIKENScientists from the RIKEN Center for Biosystems Dynamics Research (BDR) have identified key
Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX
Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

by Shanghai Jiao Tong University Journal CenterA closed-loop workflow of designing mechanobiomaterials. Credit: All authorsA group has proposed a new concept of mechanobiomaterials, which is inspired

Mechanobiomaterials: A rising field using mechanobiology principles to program functional biomaterials

by Shanghai Jiao Tong University Journal CenterA closed-loop workflow of designing mechanobiomaterials. Credit: All authorsA group has proposed a new concept of mechanobiomaterials, which is inspired
CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death
Researchers uncover news clues about the cause of craniofacial birth defects

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i
Zinc deficiency promotes Acinetobacter lung infection, mouse study shows

Zinc deficiency promotes Acinetobacter lung infection, mouse study shows

byVanderbilt University Medical CenterZn-deficient mice produce higher levels of IL-13. Credit:Nature Microbiology(2024). DOI: 10.1038/s41564-024-01849-wDietary zinc deficiency promo

Zinc deficiency promotes Acinetobacter lung infection, mouse study shows

byVanderbilt University Medical CenterZn-deficient mice produce higher levels of IL-13. Credit:Nature Microbiology(2024). DOI: 10.1038/s41564-024-01849-wDietary zinc deficiency promo
Ehrapy: A new open-source tool for analyzing complex health data

Ehrapy: A new open-source tool for analyzing complex health data

byHelmholtz Association of German Research CentresLogo ehrapy. Credit: Meshal AnsariLed by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for t

Ehrapy: A new open-source tool for analyzing complex health data

byHelmholtz Association of German Research CentresLogo ehrapy. Credit: Meshal AnsariLed by Helmholtz Munich, scientists have developed an accessible software solution specifically designed for t
Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N
Researcher identifies key mechanism in Parkinson's disease

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec
Researchers uncover genetic factors for severe Lassa fever

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan