Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Updated on: March 13,2024

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Updated on:March 13,2024

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Updated on: April 06,2024

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Updated on:April 06,2024

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Updated on: March 14,2024

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Updated on:March 14,2024

COPD and the effect of low-dose cadmium, a highly toxic metal, on airway epithelial cells

FEBRUARY 2, 2024 Editors' notesby Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainCigarette smoke exposure is associated with the development and severity of

Updated on: March 14,2024

COPD and the effect of low-dose cadmium, a highly toxic metal, on airway epithelial cells

FEBRUARY 2, 2024 Editors' notesby Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainCigarette smoke exposure is associated with the development and severity of

Updated on:March 14,2024

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p

Updated on: March 30,2024

Study uses metabolomics to identify novel diagnostic markers for chronic obstructive pulmonary disease

by Cactus CommunicationsAlterations in metabolism of lipids, amino acids, glucose, nucleotides, and pulmonary and gut microbiome play a crucial role in COPD development. These metabolites have great p

Updated on:March 30,2024

One in five people with cancer participate in medical research studies

by Fred Hutchinson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers from Fred Hutchinson Cancer Center, the American Cancer Society Cancer Action Network and peer institutions released n

Updated on: April 06,2024

One in five people with cancer participate in medical research studies

by Fred Hutchinson Cancer CenterCredit: Pixabay/CC0 Public DomainResearchers from Fred Hutchinson Cancer Center, the American Cancer Society Cancer Action Network and peer institutions released n

Updated on:April 06,2024

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on: August 12,2024

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

Updated on:August 12,2024

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i

Updated on: March 28,2024

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i

Updated on:March 28,2024

Removal of incorrect penicillin allergy labels by non-specialist health care professionals feasible, study shows

byUniversity of BirminghamCredit: CC0 Public DomainPatients who may have been mis-labeled as allergic to penicillin could be safely offered a dose of the oral antibiotic to demonstrate that they

Updated on: March 28,2024

Removal of incorrect penicillin allergy labels by non-specialist health care professionals feasible, study shows

byUniversity of BirminghamCredit: CC0 Public DomainPatients who may have been mis-labeled as allergic to penicillin could be safely offered a dose of the oral antibiotic to demonstrate that they

Updated on:March 28,2024

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i

Updated on: March 30,2024

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i

Updated on:March 30,2024

Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

by Agency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108875The A*STAR Infectious Diseases Labs (A*STAR

Updated on: April 06,2024

Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

by Agency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108875The A*STAR Infectious Diseases Labs (A*STAR

Updated on:April 06,2024

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Updated on: March 15,2024

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Updated on:March 15,2024