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Allergy&Clinical immunology
Sub Categories on Allergy&Clinical immunology
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Persistent inflammation in older adults tied to GDF3 protein signaling

Persistent inflammation in older adults tied to GDF3 protein signaling

by Alex Smith,University of Minnesota Medical SchoolGdf3 promotes SMAD-regulated genes via altered chromatin accessibility in ATMs. Credit:Nature Aging(2025). DOI: 10.1038/s43587-025-01034-6As people

Persistent inflammation in older adults tied to GDF3 protein signaling

by Alex Smith,University of Minnesota Medical SchoolGdf3 promotes SMAD-regulated genes via altered chromatin accessibility in ATMs. Credit:Nature Aging(2025). DOI: 10.1038/s43587-025-01034-6As people
Prolonged hydrodistention may provide longer symptom relief in interstitial cystitis

Prolonged hydrodistention may provide longer symptom relief in interstitial cystitis

by Elana GotkineFor patients with interstitial cystitis (IC), longer cystoscopic hydrodistention (HD) times may result in improved efficacy and longer symptom relief, according to a studypublishedonli

Prolonged hydrodistention may provide longer symptom relief in interstitial cystitis

by Elana GotkineFor patients with interstitial cystitis (IC), longer cystoscopic hydrodistention (HD) times may result in improved efficacy and longer symptom relief, according to a studypublishedonli
What determines the fate of a T cell? Research highlights cellular 'housekeeping' mechanism

What determines the fate of a T cell? Research highlights cellular 'housekeeping' mechanism

byMax Delbrück Center for Molecular MedicineT stem cells normally undergo asymmetric cell division (left) whereby one daughter cell becomes a long-lived memory T cell. When autophagy is disrupted, bot

What determines the fate of a T cell? Research highlights cellular 'housekeeping' mechanism

byMax Delbrück Center for Molecular MedicineT stem cells normally undergo asymmetric cell division (left) whereby one daughter cell becomes a long-lived memory T cell. When autophagy is disrupted, bot
Soil bacteria and fungi emerge as top predictors of childhood allergic disease

Soil bacteria and fungi emerge as top predictors of childhood allergic disease

byAmerican Geophysical UnionCredit: Pixabay/CC0 Public DomainThe unique blend of fungi and bacteria in a region's soil may be the strongest factor explaining its rates of childhood allergic diseas

Soil bacteria and fungi emerge as top predictors of childhood allergic disease

byAmerican Geophysical UnionCredit: Pixabay/CC0 Public DomainThe unique blend of fungi and bacteria in a region's soil may be the strongest factor explaining its rates of childhood allergic diseas
Most parents are aware of early peanut introduction guidelines—but confused about the details

Most parents are aware of early peanut introduction guidelines—but confused about the details

byAnn & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainFeeding babies peanut-containing foods as early as possible can help prevent peanut allergy, but a new st

Most parents are aware of early peanut introduction guidelines—but confused about the details

byAnn & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainFeeding babies peanut-containing foods as early as possible can help prevent peanut allergy, but a new st
Liver cell reprogramming boosts T cell function in aging immune systems

Liver cell reprogramming boosts T cell function in aging immune systems

byMassachusetts Institute of TechnologyCredit: CC0 Public DomainAs people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, mak

Liver cell reprogramming boosts T cell function in aging immune systems

byMassachusetts Institute of TechnologyCredit: CC0 Public DomainAs people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, mak
Evaluating the impact of heat-inactivated bacteria on age-related inflammation

Evaluating the impact of heat-inactivated bacteria on age-related inflammation

byShinshu UniversityHeat-killed L. kefiri YRC2606 attenuates immunosenescence by suppressing IL-6/STAT3 signaling and alleviating thymic atrophy, thereby reducing inflammatory cytokine production and

Evaluating the impact of heat-inactivated bacteria on age-related inflammation

byShinshu UniversityHeat-killed L. kefiri YRC2606 attenuates immunosenescence by suppressing IL-6/STAT3 signaling and alleviating thymic atrophy, thereby reducing inflammatory cytokine production and
High stakes of early immune development revealed—and a potential probiotic fix

High stakes of early immune development revealed—and a potential probiotic fix

byThe Scripps Research InstituteThe study found that antibiotic use in early life can reduce the number of healthy gut bacteria required to support immune system development. However, administering pr

High stakes of early immune development revealed—and a potential probiotic fix

byThe Scripps Research InstituteThe study found that antibiotic use in early life can reduce the number of healthy gut bacteria required to support immune system development. However, administering pr
Key lung immune cells can intensify allergic reactions

Key lung immune cells can intensify allergic reactions

byVIB (the Flanders Institute for Biotechnology)Credit:Immunity(2025). DOI: 10.1016/j.immuni.2025.11.015Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal

Key lung immune cells can intensify allergic reactions

byVIB (the Flanders Institute for Biotechnology)Credit:Immunity(2025). DOI: 10.1016/j.immuni.2025.11.015Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal
Eczema injectable drug provides quick itch relief, clinical trial results show

Eczema injectable drug provides quick itch relief, clinical trial results show

by Dennis ThompsonA recently approved injectable eczema drug provides quick itch relief to patients with the maddening skin disease, a new study says.Nemolizumab(Nemluvio) relieved itchiness within tw

Eczema injectable drug provides quick itch relief, clinical trial results show

by Dennis ThompsonA recently approved injectable eczema drug provides quick itch relief to patients with the maddening skin disease, a new study says.Nemolizumab(Nemluvio) relieved itchiness within tw