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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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The molecules behind metastasis

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art

The molecules behind metastasis

by Greta Friar,Whitehead Institute for Biomedical ResearchBreast cancer stem cells (red) that have reached the lung begin to divide into clusters that could become metastatic tumors. Credit: Art
Have recent efforts successfully boosted adolescent and young adult enrollment in cancer clinical trials?

Have recent efforts successfully boosted adolescent and young adult enrollment in cancer clinical trials?

byWileyDistribution of trial types by year. For each calendar year, the number of actively accruing trials for which adolescent and young adult patients were eligible is represented as a stacked

Have recent efforts successfully boosted adolescent and young adult enrollment in cancer clinical trials?

byWileyDistribution of trial types by year. For each calendar year, the number of actively accruing trials for which adolescent and young adult patients were eligible is represented as a stacked
How tumors mutate their way out of a crisis—and become drug resistant in the process

How tumors mutate their way out of a crisis—and become drug resistant in the process

byWeizmann Institute of ScienceHuman lung cancer cells under the microscope, before (left) and after (right) treatment with an anticancer drug, which causes DNA breaks (green) in the cell nuclei

How tumors mutate their way out of a crisis—and become drug resistant in the process

byWeizmann Institute of ScienceHuman lung cancer cells under the microscope, before (left) and after (right) treatment with an anticancer drug, which causes DNA breaks (green) in the cell nuclei
Even when at low risk, some women should remove fallopian tubes to avoid ovarian cancer, say experts

Even when at low risk, some women should remove fallopian tubes to avoid ovarian cancer, say experts

by Cara MurezMore women, even those at low risk for ovarian cancer, who have finished having children should have their fallopian tubes removed as a precaution to prevent the deadly disease, a leading

Even when at low risk, some women should remove fallopian tubes to avoid ovarian cancer, say experts

by Cara MurezMore women, even those at low risk for ovarian cancer, who have finished having children should have their fallopian tubes removed as a precaution to prevent the deadly disease, a leading
Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell

Tumor ammonia levels inhibit T cell growth, impact immunotherapy: Study

by Anna Megdell,University of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2021). DOI: 10.1172/JCI143691High levels of ammonia in tumors leads to fewer T cell
Genetic testing is important for women with breast cancer, expert says

Genetic testing is important for women with breast cancer, expert says

by Rebecca Biason,University of TorontoCredit: Pixabay/CC0 Public DomainFor close to two decades Professor Kelly Metcalfe, a senior scientist at Women's College Research Institute and associ

Genetic testing is important for women with breast cancer, expert says

by Rebecca Biason,University of TorontoCredit: Pixabay/CC0 Public DomainFor close to two decades Professor Kelly Metcalfe, a senior scientist at Women's College Research Institute and associ
The surprising link between circadian disruption and cancer may have to do with temperature

The surprising link between circadian disruption and cancer may have to do with temperature

byThe Scripps Research InstituteFor mice placed in ‘chronic jet lag’ (CJL) conditions, they showed a 68% increase in tumor burden when compared to mice placed in 12 hours of light, 12 hours of d

The surprising link between circadian disruption and cancer may have to do with temperature

byThe Scripps Research InstituteFor mice placed in ‘chronic jet lag’ (CJL) conditions, they showed a 68% increase in tumor burden when compared to mice placed in 12 hours of light, 12 hours of d
Maximizing the potential of 3D-patient tumor avatars for next-generation precision oncology

Maximizing the potential of 3D-patient tumor avatars for next-generation precision oncology

by Terasaki Institute for Biomedical Innovation3D Patient Tumor Avatars (3D-PTAs) are part of a proposed integrative platform to provide optimal treatment selections for cancer patients. Such a platfo

Maximizing the potential of 3D-patient tumor avatars for next-generation precision oncology

by Terasaki Institute for Biomedical Innovation3D Patient Tumor Avatars (3D-PTAs) are part of a proposed integrative platform to provide optimal treatment selections for cancer patients. Such a platfo
Active surveillance feasible for low-risk thyroid cancer

Active surveillance feasible for low-risk thyroid cancer

Active surveillance may be a viable strategy for most diagnosed thyroid cancers, according to a study published online Sept. 15 inJAMA Oncology.Allen S. Ho, M.D., from Cedars-Sinai Medical Cente

Active surveillance feasible for low-risk thyroid cancer

Active surveillance may be a viable strategy for most diagnosed thyroid cancers, according to a study published online Sept. 15 inJAMA Oncology.Allen S. Ho, M.D., from Cedars-Sinai Medical Cente
Clues found regarding tumor suppressor gene's breast cancer activity

Clues found regarding tumor suppressor gene's breast cancer activity

byJohns Hopkins University School of MedicineCredit: Saraswati Sukumar and Priya PaiResearchers at the Johns Hopkins Kimmel Cancer Center have revealed how the gene HOXA5 may work to suppress fo

Clues found regarding tumor suppressor gene's breast cancer activity

byJohns Hopkins University School of MedicineCredit: Saraswati Sukumar and Priya PaiResearchers at the Johns Hopkins Kimmel Cancer Center have revealed how the gene HOXA5 may work to suppress fo
Gradual increase in daily activity, psychological therapy can improve mental health for cancer patients and survivors

Gradual increase in daily activity, psychological therapy can improve mental health for cancer patients and survivors

by European Organisation for Research and Treatment of CancerMs. Astrid Lahousse. Credit: Ms. Astrid LahousseCancer patients and survivors have better mental and physical health and quality of life if

Gradual increase in daily activity, psychological therapy can improve mental health for cancer patients and survivors

by European Organisation for Research and Treatment of CancerMs. Astrid Lahousse. Credit: Ms. Astrid LahousseCancer patients and survivors have better mental and physical health and quality of life if
Wear and tear from lifelong stress can increase cancer mortality

Wear and tear from lifelong stress can increase cancer mortality

byMedical College of Georgia at Augusta UniversityDr. Justin X. Moore. Credit: Mike Holahan, Augusta UniversityThe wear and tear on the body from chronic and lifelong stress can also lead to an

Wear and tear from lifelong stress can increase cancer mortality

byMedical College of Georgia at Augusta UniversityDr. Justin X. Moore. Credit: Mike Holahan, Augusta UniversityThe wear and tear on the body from chronic and lifelong stress can also lead to an