Metabolic reprogramming of tumor-associated macrophages

by Cactus CommunicationsThe article discusses the metabolic pathways involved in reprograming tumor-associated macrophages, immune cells which contribute to tumor growth. Credit: Yi Zhang from Zhengzh

Updated on: January 22,2024 13

Metabolic reprogramming of tumor-associated macrophages

by Cactus CommunicationsThe article discusses the metabolic pathways involved in reprograming tumor-associated macrophages, immune cells which contribute to tumor growth. Credit: Yi Zhang from Zhengzh

Updated on:January 22,2024 13

Platinum-based chemotherapy distribution within a tumor may predict ovarian cancer treatment resistance

byNagoya UniversityTumor tissue is indicated with the filled arrow and stroma with the unfilled arrow (upper photo).A platinum-resistant patient showing platinum (blue in the bottom photo) mostl

Updated on: January 22,2024 19

Platinum-based chemotherapy distribution within a tumor may predict ovarian cancer treatment resistance

byNagoya UniversityTumor tissue is indicated with the filled arrow and stroma with the unfilled arrow (upper photo).A platinum-resistant patient showing platinum (blue in the bottom photo) mostl

Updated on:January 22,2024 19

Review covers progress in immunotherapy for esophageal cancer

by Cactus CommunicationsMultiple ongoing clinical trials are being conducted to test the potential of ICIs as an adjuvant therapy for resectable esophageal cancer. The results of these trials could ce

Updated on: January 22,2024 18

Review covers progress in immunotherapy for esophageal cancer

by Cactus CommunicationsMultiple ongoing clinical trials are being conducted to test the potential of ICIs as an adjuvant therapy for resectable esophageal cancer. The results of these trials could ce

Updated on:January 22,2024 18

Determinants of overall survival in metastatic uveal melanoma identified

by Elana GotkineFactors associated with improved survival in metastatic uveal melanoma include female sex and use of anti‐cytotoxic T lymphocyte-associated antigen (CTLA)‐4 and anti‐programmed cell de

Updated on: January 22,2024 20

Determinants of overall survival in metastatic uveal melanoma identified

by Elana GotkineFactors associated with improved survival in metastatic uveal melanoma include female sex and use of anti‐cytotoxic T lymphocyte-associated antigen (CTLA)‐4 and anti‐programmed cell de

Updated on:January 22,2024 20

Cervical cancer discovery offers major new clue to better understand the disease

byUniversity College LondonDifferences in the tumor microenvironment between cervical cancer subgroups. Plot showing median abundances (x-axis) and median differences (%, y-axis) for different c

Updated on: January 22,2024 11

Cervical cancer discovery offers major new clue to better understand the disease

byUniversity College LondonDifferences in the tumor microenvironment between cervical cancer subgroups. Plot showing median abundances (x-axis) and median differences (%, y-axis) for different c

Updated on:January 22,2024 11

Experts call for better cancer tests to tailor treatment

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainGreater use of cancer tests is the key to tailoring use of new treatments for patients more precisely and so increasing their chanc

Updated on: January 22,2024 19

Experts call for better cancer tests to tailor treatment

byInstitute of Cancer ResearchCredit: Pixabay/CC0 Public DomainGreater use of cancer tests is the key to tailoring use of new treatments for patients more precisely and so increasing their chanc

Updated on:January 22,2024 19

MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on: January 22,2024 16

MTAP loss in metastatic breast cancer patients: Genomic landscape

by Impact Journals LLCMechanism of action of MTAP along with downstream effects from its loss. Abbreviations: MTAP: methylthioadenosine phosphorylase; MTR1P: 5-methylthioribose-1-phosphate; ODC: Ornit

Updated on:January 22,2024 16

How tumors suppress the development of metastases

byGerman Cancer Research CenterCredit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20202595Why do metastases often only appear after the original tumor has been surgicall

Updated on: January 22,2024 13

How tumors suppress the development of metastases

byGerman Cancer Research CenterCredit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20202595Why do metastases often only appear after the original tumor has been surgicall

Updated on:January 22,2024 13

'Hard to lose' mutations in tumors may predict response to immunotherapy

byJohns Hopkins University School of MedicineThe figure shows the interactions between immune cells (white) and tumor cells harboring persistent mutations (red) in the context of immunotherapy (

Updated on: January 22,2024 12

'Hard to lose' mutations in tumors may predict response to immunotherapy

byJohns Hopkins University School of MedicineThe figure shows the interactions between immune cells (white) and tumor cells harboring persistent mutations (red) in the context of immunotherapy (

Updated on:January 22,2024 12

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep

Updated on: January 22,2024 15

Stopping the spread: Targeting tumor metastasis

by Tokyo Medical and Dental UniversityTakahashi et al. show that TGF-β generates a population of cancer cells under cell cycle arrest in G1 phase with high motility by inducing unique Slug/HMGA2-indep

Updated on:January 22,2024 15

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on: January 22,2024 10

Ethnic diversity and disparities in access to genetic testing impact prostate cancer development and treatment

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainMore than 1.4 million men were diagnosed with prostate cancer in 2020 globally, but the molecular characteristics of the

Updated on:January 22,2024 10

The tumor environment can affect breast cancer prognosis

byLund UniversityFlowchart of included and excluded patients and representative pictures of each CAV1 staining category in stroma and cytoplasm. Credit:Translational Oncology(2022).

Updated on: January 22,2024 20

The tumor environment can affect breast cancer prognosis

byLund UniversityFlowchart of included and excluded patients and representative pictures of each CAV1 staining category in stroma and cytoplasm. Credit:Translational Oncology(2022).

Updated on:January 22,2024 20