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New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

by Allessandra DiCorato,Broad Institute of MIT and HarvardCytokine production map by cell type. Credit:Nature(2023). DOI: 10.1038/s41586-023-06816-9The immune system can carry out ma

New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

by Allessandra DiCorato,Broad Institute of MIT and HarvardCytokine production map by cell type. Credit:Nature(2023). DOI: 10.1038/s41586-023-06816-9The immune system can carry out ma
FDA approves new antibiotic for three indications

FDA approves new antibiotic for three indications

by Lori SolomonThe U.S. Food and Drug Administration has approved the antibiotic Zevtera (ceftobiprole medocaril sodium for injection) for three different indications, including treatment of adults wi

FDA approves new antibiotic for three indications

by Lori SolomonThe U.S. Food and Drug Administration has approved the antibiotic Zevtera (ceftobiprole medocaril sodium for injection) for three different indications, including treatment of adults wi
Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic
Evaluating selpercatinib for the treatment of non-small cell lung cancer

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control
Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (
Prolonged use of certain hormone drugs linked to increased brain tumor risk

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto
Patients with device-detected atrial fibrillation and multiple comorbidities do not benefit from anticoagulation: Study

Patients with device-detected atrial fibrillation and multiple comorbidities do not benefit from anticoagulation: Study

by Angelika Leute, Kompetenznetz Vorhofflimmern e.V. (AFNET)Credit:European Heart Journal(2024). DOI: 10.1093/eurheartj/ehae225In patients with device-detected atrial fibrillation and a hi

Patients with device-detected atrial fibrillation and multiple comorbidities do not benefit from anticoagulation: Study

by Angelika Leute, Kompetenznetz Vorhofflimmern e.V. (AFNET)Credit:European Heart Journal(2024). DOI: 10.1093/eurheartj/ehae225In patients with device-detected atrial fibrillation and a hi
CRISPR-based mapping uncovers 'switches' for immune genes central to health

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t
Siris tree leaves hold promise for stopping spread of breast cancer cells, say researchers

Siris tree leaves hold promise for stopping spread of breast cancer cells, say researchers

by University of SharjahAlbizia lebbeck—Shirish/Siris Tree. Credit: Wikimedia Commons,CC BY-SA 4.0Albizia lebbeck is the scientific name of the siris tree, which may hold the promise of wor

Siris tree leaves hold promise for stopping spread of breast cancer cells, say researchers

by University of SharjahAlbizia lebbeck—Shirish/Siris Tree. Credit: Wikimedia Commons,CC BY-SA 4.0Albizia lebbeck is the scientific name of the siris tree, which may hold the promise of wor
How does HIV get into the cell's center to kickstart infection?

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06
Five-day antibiotic course noninferior for pediatric febrile UTI

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c