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Scientists improve the equation in FDA guidance predicting drug interactions

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und
Beating back bitter taste in medicine: Scientists discover that diabetes drug is partially effective as a bitter blocker

Beating back bitter taste in medicine: Scientists discover that diabetes drug is partially effective as a bitter blocker

by Karen Kreeger,Monell Chemical Senses CenterCredit: CC0 Public DomainThe bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are part

Beating back bitter taste in medicine: Scientists discover that diabetes drug is partially effective as a bitter blocker

by Karen Kreeger,Monell Chemical Senses CenterCredit: CC0 Public DomainThe bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are part
Patients regain much weight after stopping new obesity drug: Study

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On
Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley
Tracking ticks in Georgia to help monitor emerging diseases

Tracking ticks in Georgia to help monitor emerging diseases

by Carol Clark,Emory UniversityMapping the lone star tick is another step in a comprehensive Emory project to track and monitor the array of tick species in Georgia and the diseases that they ca

Tracking ticks in Georgia to help monitor emerging diseases

by Carol Clark,Emory UniversityMapping the lone star tick is another step in a comprehensive Emory project to track and monitor the array of tick species in Georgia and the diseases that they ca
Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have tested the feasibility of using human cell transdifferentiation with RNA

Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have tested the feasibility of using human cell transdifferentiation with RNA
LSD, a future anti-anxiety pill?

LSD, a future anti-anxiety pill?

LSD, a future anti-anxiety pill?byMcGill UniversityCredit: CC0 Public DomainThe craze for psychedelics used for therapeutic purposes is real. However, the scientific evidence supporting their ef

LSD, a future anti-anxiety pill?

LSD, a future anti-anxiety pill?byMcGill UniversityCredit: CC0 Public DomainThe craze for psychedelics used for therapeutic purposes is real. However, the scientific evidence supporting their ef
New study aims to define the progeria phenome

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes
New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

by Marcus Horwitz,University of California, Los AngelesBurkholderia pseudomallei infecting a human cell. The bacteria (red) are polymerizing actin (green). Credit: Christopher T. FrenchIn a mous

New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

by Marcus Horwitz,University of California, Los AngelesBurkholderia pseudomallei infecting a human cell. The bacteria (red) are polymerizing actin (green). Credit: Christopher T. FrenchIn a mous
Scientists develop tunable organic active neural probe enabling near-sensor signal processing

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li
Researchers race to develop Paxlovid replacement

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor
New study finds diabetes drug may reduce risk for colorectal cancer

New study finds diabetes drug may reduce risk for colorectal cancer

byCase Western Reserve UniversityCredit: CC0 Public DomainA study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce

New study finds diabetes drug may reduce risk for colorectal cancer

byCase Western Reserve UniversityCredit: CC0 Public DomainA study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce