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Medical research
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Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv
Study looks at ways to predict when a migraine attack will occur

Study looks at ways to predict when a migraine attack will occur

JANUARY 24, 2024byAmerican Academy of NeurologyCredit: Sasha Wolff/WikipediaMigraine is often under-diagnosed and untreated, and even when it is treated, it can be difficult to treat early enoug

Study looks at ways to predict when a migraine attack will occur

JANUARY 24, 2024byAmerican Academy of NeurologyCredit: Sasha Wolff/WikipediaMigraine is often under-diagnosed and untreated, and even when it is treated, it can be difficult to treat early enoug
Researchers identify promising protein candidate for metabolic disease treatment

Researchers identify promising protein candidate for metabolic disease treatment

byUniversity of SaskatchewanHepG2/C3A cells express NUCB1/NLP and NUCB2/NESF-1. Credit:Communications Biology(2024). DOI: 10.1038/s42003-024-06314-2University of Saskatchewan (USask)

Researchers identify promising protein candidate for metabolic disease treatment

byUniversity of SaskatchewanHepG2/C3A cells express NUCB1/NLP and NUCB2/NESF-1. Credit:Communications Biology(2024). DOI: 10.1038/s42003-024-06314-2University of Saskatchewan (USask)
Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules
Study eases concern at antipsychotics use in pregnancy

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o
How the brain develops in unborn babies

How the brain develops in unborn babies

byUniversity of MontrealProtein–protein interaction networks for maternal, fetal, and famine genes. Deregulated (A) maternal, (B) fetal, or (C) famine genes were used as a query to obtain physic

How the brain develops in unborn babies

byUniversity of MontrealProtein–protein interaction networks for maternal, fetal, and famine genes. Deregulated (A) maternal, (B) fetal, or (C) famine genes were used as a query to obtain physic
Scientists harness ultrasound for drug delivery and tissue implantation

Scientists harness ultrasound for drug delivery and tissue implantation

by Technion - Israel Institute of TechnologyUltrasound mediated polymerization of acousto-sensitive biomaterials. Credit: Small Methods (2024). DOI: 10.1002/smtd.202301197Research presents an advance

Scientists harness ultrasound for drug delivery and tissue implantation

by Technion - Israel Institute of TechnologyUltrasound mediated polymerization of acousto-sensitive biomaterials. Credit: Small Methods (2024). DOI: 10.1002/smtd.202301197Research presents an advance
Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

by Ann & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainThe lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children's Research Institute at Ann & R

Biological mechanism discovered that could lead to new treatments for neurological disorders and cancers

by Ann & Robert H. Lurie Children's Hospital of ChicagoCredit: Pixabay/CC0 Public DomainThe lab of Yongchao C. Ma, Ph.D., at Stanley Manne Children's Research Institute at Ann & R
Materiobiology: Advances in aging bone regeneration material development

Materiobiology: Advances in aging bone regeneration material development

byScience China PressThe new development process for aging bone regeneration materials focuses on in-depth research of dysfunctional mechanisms, the development of a biomaterial 'toolbox&#39

Materiobiology: Advances in aging bone regeneration material development

byScience China PressThe new development process for aging bone regeneration materials focuses on in-depth research of dysfunctional mechanisms, the development of a biomaterial 'toolbox&#39
Clinical trial: New dual therapy could revolutionize treatment of urothelial and bladder cancers

Clinical trial: New dual therapy could revolutionize treatment of urothelial and bladder cancers

by Georgia Gowing,Macquarie UniversityDr. Alison Zhang. Credit: Macquarie UniversityAn international clinical trial of a treatment for advanced urothelial cancer has found a new dual therapy can

Clinical trial: New dual therapy could revolutionize treatment of urothelial and bladder cancers

by Georgia Gowing,Macquarie UniversityDr. Alison Zhang. Credit: Macquarie UniversityAn international clinical trial of a treatment for advanced urothelial cancer has found a new dual therapy can
New technique improves imaging for lymphatic system

New technique improves imaging for lymphatic system

bySPIEA multispectral imaging system helps visualize and measure circulation within lymphatic vessels. Credit:Journal of Biomedical Optics(2024). DOI: 10.1117/1.JBO.29.10.106001The l

New technique improves imaging for lymphatic system

bySPIEA multispectral imaging system helps visualize and measure circulation within lymphatic vessels. Credit:Journal of Biomedical Optics(2024). DOI: 10.1117/1.JBO.29.10.106001The l