Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on: March 14,2024 16

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on:March 14,2024 16

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection

Updated on: April 28,2024 0

Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks

by Association for Professionals in Infection ControlCredit: CC0 Public DomainA newstudypublished today in theAmerican Journal of Infection Control (AJIC)reports the infection

Updated on:April 28,2024 0

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Updated on: March 30,2024 3

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Updated on:March 30,2024 3

Research suggests chronic pain is different for males and females

JANUARY 24, 2024by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainA University of Alberta research team has uncovered differences in the way male and female mice develo

Updated on: March 27,2024 6

Research suggests chronic pain is different for males and females

JANUARY 24, 2024by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainA University of Alberta research team has uncovered differences in the way male and female mice develo

Updated on:March 27,2024 6

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N

Updated on: March 25,2024 6

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N

Updated on:March 25,2024 6

Removal of incorrect penicillin allergy labels by non-specialist health care professionals feasible, study shows

byUniversity of BirminghamCredit: CC0 Public DomainPatients who may have been mis-labeled as allergic to penicillin could be safely offered a dose of the oral antibiotic to demonstrate that they

Updated on: March 28,2024 0

Removal of incorrect penicillin allergy labels by non-specialist health care professionals feasible, study shows

byUniversity of BirminghamCredit: CC0 Public DomainPatients who may have been mis-labeled as allergic to penicillin could be safely offered a dose of the oral antibiotic to demonstrate that they

Updated on:March 28,2024 0

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Updated on: March 13,2024 6

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Updated on:March 13,2024 6

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

Updated on: March 14,2024 5

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

Updated on:March 14,2024 5

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on: March 28,2024 0

CBD products don't ease pain and are potentially harmful, study finds

by Vittoria D'Alessio,University of BathCredit: Unsplash/CC0 Public DomainThere is no evidence that CBD products reduce chronic pain, and taking them is a waste of money and potentially harm

Updated on:March 28,2024 0

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Updated on: March 30,2024 4

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Updated on:March 30,2024 4

How the brain develops in unborn babies

byUniversity of MontrealProtein–protein interaction networks for maternal, fetal, and famine genes. Deregulated (A) maternal, (B) fetal, or (C) famine genes were used as a query to obtain physic

Updated on: March 13,2024 14

How the brain develops in unborn babies

byUniversity of MontrealProtein–protein interaction networks for maternal, fetal, and famine genes. Deregulated (A) maternal, (B) fetal, or (C) famine genes were used as a query to obtain physic

Updated on:March 13,2024 14

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on: March 28,2024 1

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on:March 28,2024 1