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New tool improves the search for genes that cause diseases

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch
Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit
Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

byChildren's Hospital of PhiladelphiaCredit:Molecular Therapy(2024). DOI: 10.1016/j.ymthe.2024.08.015Researchers from Children's Hospital of Philadelphia (CHOP) have tested a

Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

byChildren's Hospital of PhiladelphiaCredit:Molecular Therapy(2024). DOI: 10.1016/j.ymthe.2024.08.015Researchers from Children's Hospital of Philadelphia (CHOP) have tested a
Researchers uncover genetic factors for severe Lassa fever

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan
Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease
New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs
New insight into gene uncovers its link to incurable birth defect

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir
Common human gene mutations linked to a range of health conditions

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w
Could artificial intelligence help or hurt medical research articles?

Could artificial intelligence help or hurt medical research articles?

FEBRUARY 6, 2024byIndiana University School of MedicineOverview of experimental study design employed to examine the utility of using ChatGPT to write scientific review articles about the inters

Could artificial intelligence help or hurt medical research articles?

FEBRUARY 6, 2024byIndiana University School of MedicineOverview of experimental study design employed to examine the utility of using ChatGPT to write scientific review articles about the inters
Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N
Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of
Research suggests chronic pain is different for males and females

Research suggests chronic pain is different for males and females

JANUARY 24, 2024by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainA University of Alberta research team has uncovered differences in the way male and female mice develo

Research suggests chronic pain is different for males and females

JANUARY 24, 2024by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainA University of Alberta research team has uncovered differences in the way male and female mice develo