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New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r
Biological engineers discover why a promising drug failed in clinical trials

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima
New guidelines for reporting clinical trials of biofield therapies released

New guidelines for reporting clinical trials of biofield therapies released

byMary Ann Liebert, IncCredit: Unsplash/CC0 Public DomainNewguidelinesfor reporting clinical trials of biofield therapies are presented in theJournal of Integrative and Complem

New guidelines for reporting clinical trials of biofield therapies released

byMary Ann Liebert, IncCredit: Unsplash/CC0 Public DomainNewguidelinesfor reporting clinical trials of biofield therapies are presented in theJournal of Integrative and Complem
Protein production glitches in Huntington's disease revealed

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe
Competitive swimming program for young people with severe cerebral palsy reverses motor decline

Competitive swimming program for young people with severe cerebral palsy reverses motor decline

byUniversity of QueenslandParaSTART participant Nate preparing for a swim training session. Credit: ParaSTART program, University of QueenslandA competitive swimming program developed by Univers

Competitive swimming program for young people with severe cerebral palsy reverses motor decline

byUniversity of QueenslandParaSTART participant Nate preparing for a swim training session. Credit: ParaSTART program, University of QueenslandA competitive swimming program developed by Univers
Enhancing hypoxia-activated prodrug anticancer therapy

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres
Key mechanism governing bone marrow stem cells opens door to new therapies

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste

Key mechanism governing bone marrow stem cells opens door to new therapies

by King's College LondonCredit: Pixabay/CC0 Public DomainA key mechanism controlling how bone marrow stem cells work has been revealed in a new study, shining a light on the principles of ste
Alcohol may help flush out arsenic from the body, study finds

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i
Familial Alzheimer's disease transferred via bone marrow transplant in mice

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr
ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r
Researchers uncover 'circular logic' of RNAs in Parkinson's disease

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used
Serious flu damage prevented by compound that blocks unnecessary cell death

Serious flu damage prevented by compound that blocks unnecessary cell death

byTufts UniversityCredit: Pixabay/CC0 Public DomainAs lung cells are killed by the influenza virus, they burst open, releasing molecular signals that trigger the immune cells that can combat the

Serious flu damage prevented by compound that blocks unnecessary cell death

byTufts UniversityCredit: Pixabay/CC0 Public DomainAs lung cells are killed by the influenza virus, they burst open, releasing molecular signals that trigger the immune cells that can combat the