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Simulations reveal mechanism behind protein buildup in Parkinson's disease

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod

Simulations reveal mechanism behind protein buildup in Parkinson's disease

by Emily Packer,eLifeA schematic showcasing the process of liquid-liquid phase separation of αS. Credit:eLife(2024). DOI: 10.7554/eLife.95180.1Researchers have used computational mod
CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death
Common dry cleaning chemical linked to Parkinson's

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi

Common dry cleaning chemical linked to Parkinson's

MARCH 14, 2023byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainA common and widely used chemical may be fueling the rise of the world's fastest growing brain conditi
Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com
Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever
Chemical and computational advances enable 2D proteomics measurements of spatial signals

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet
New research into life-threatening birth defect of the diaphragm

New research into life-threatening birth defect of the diaphragm

by Birgit Pfeiffer,Leipzig UniversityHypoplastic lungs of human fetuses with CDH have increased macrophage density and up-regulation of inflammatory mediators. Credit:Science Advances&nbsp

New research into life-threatening birth defect of the diaphragm

by Birgit Pfeiffer,Leipzig UniversityHypoplastic lungs of human fetuses with CDH have increased macrophage density and up-regulation of inflammatory mediators. Credit:Science Advances&nbsp
Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

by Zara Abrams,Keck School of Medicine of USCCredit: CC0 Public DomainSmoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-rel

Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

by Zara Abrams,Keck School of Medicine of USCCredit: CC0 Public DomainSmoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-rel
Microbiome changes in chronic liver disease highlight need for personalized treatment

Microbiome changes in chronic liver disease highlight need for personalized treatment

byKing's College LondonMicrobial diversity and community structure alterations by cirrhosis severity. Credit:Journal of Hepatology(2024). DOI: 10.1016/j.jhep.2024.09.046The bacte

Microbiome changes in chronic liver disease highlight need for personalized treatment

byKing's College LondonMicrobial diversity and community structure alterations by cirrhosis severity. Credit:Journal of Hepatology(2024). DOI: 10.1016/j.jhep.2024.09.046The bacte
Researchers create a new tool to rapidly diagnose genetic mutations

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g
Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti

Quest for personalized medicine hits a snag: Current models have limited effectiveness to predict treatments, says study

JANUARY 11, 2024by Bill Hathaway,Yale UniversityCredit: Unsplash/CC0 Public DomainThe quest for personalized medicine, a medical approach in which practitioners use a patient's unique geneti