FDA approves Abecma for relapsed, refractory multiple myeloma

by Lori SolomonThe U.S. Food and Drug Administration has approved Abecma (idecabtagene vicleucel) as a personalized CAR T-cell therapy for triple-class exposed relapsed or refractory multiple myeloma.

Updated on: April 28,2024 0

FDA approves Abecma for relapsed, refractory multiple myeloma

by Lori SolomonThe U.S. Food and Drug Administration has approved Abecma (idecabtagene vicleucel) as a personalized CAR T-cell therapy for triple-class exposed relapsed or refractory multiple myeloma.

Updated on:April 28,2024 0

Time of death or personal autonomy? Cancer patients prefer knowing functional prognosis over life expectancy

byUniversity of TsukubaCredit: AI-generated imageProviding prognostic information is a vital component of cancer patient care. However, the specific information cancer patients prefer to receive

Updated on: January 04,2024 8

Time of death or personal autonomy? Cancer patients prefer knowing functional prognosis over life expectancy

byUniversity of TsukubaCredit: AI-generated imageProviding prognostic information is a vital component of cancer patient care. However, the specific information cancer patients prefer to receive

Updated on:January 04,2024 8

Mechanism for silencing gene expression targets the culprit behind a deadly liver cancer

by Sanford M. Simon,Rockefeller UniversityASGR1 in FLC. (A) RNA expression analysis of ASGR1 across patient samples. (B) Immunofluorescence of ASGR1 in tumor-adjacent healthy liver, primary tumo

Updated on: March 20,2024 10

Mechanism for silencing gene expression targets the culprit behind a deadly liver cancer

by Sanford M. Simon,Rockefeller UniversityASGR1 in FLC. (A) RNA expression analysis of ASGR1 across patient samples. (B) Immunofluorescence of ASGR1 in tumor-adjacent healthy liver, primary tumo

Updated on:March 20,2024 10

Era of hope for patients with lung cancer

by Alex OsiadaczCredit: Pixabay/CC0 Public DomainNovember is Lung Cancer Awareness month. Lung cancer is the most common cancer worldwide, with more than 2.1 million cases, according to the American L

Updated on: December 22,2023 8

Era of hope for patients with lung cancer

by Alex OsiadaczCredit: Pixabay/CC0 Public DomainNovember is Lung Cancer Awareness month. Lung cancer is the most common cancer worldwide, with more than 2.1 million cases, according to the American L

Updated on:December 22,2023 8

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on: February 20,2024 13

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on:February 20,2024 13

Performance on exercise test predicts risk of death from cardiovascular disease and cancer

by European Society of CardiologyCredit: CC0 Public DomainPerformance on an exercise test predicts the risk of death from cardiovascular disease, cancer, and other causes, reports a study present

Updated on: May 05,2024 17

Performance on exercise test predicts risk of death from cardiovascular disease and cancer

by European Society of CardiologyCredit: CC0 Public DomainPerformance on an exercise test predicts the risk of death from cardiovascular disease, cancer, and other causes, reports a study present

Updated on:May 05,2024 17

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on: December 25,2023 10

Extreme phenotype approach identifies rare ATR variants as potential male breast cancer susceptibility alleles

by Impact Journals LLCImpact of splicing variants. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28358In oncogenetics, some patients could be considered as "extreme phenotypes,&qu

Updated on:December 25,2023 10

Management of refractory or relapsed classic Hodgkin lymphoma in Brazil

by Impact Journals LLCHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0Anew review papertitled "Current perspect

Updated on: December 28,2023 15

Management of refractory or relapsed classic Hodgkin lymphoma in Brazil

by Impact Journals LLCHodgkin lymphoma, nodular lymphocyte predominant (high-power view) Credit: Gabriel Caponetti, MD./Wikipedia/CC BY-SA 3.0Anew review papertitled "Current perspect

Updated on:December 28,2023 15

Guideline updated for initial management of advanced prostate cancer

by Elana GotkineFor patients with noncastrate advanced prostate cancer, docetaxel, abiraterone, enzalutamide, apalutamide, or darolutamide are each recommended as standards of care with androgen depri

Updated on: January 08,2024 10

Guideline updated for initial management of advanced prostate cancer

by Elana GotkineFor patients with noncastrate advanced prostate cancer, docetaxel, abiraterone, enzalutamide, apalutamide, or darolutamide are each recommended as standards of care with androgen depri

Updated on:January 08,2024 10

New research finds oral leukemia therapy to work as well as intravenous decitabine

by Hackensack Meridian HealthCredit: Pixabay/CC0 Public DomainResearchers at Hackensack Meridian's John Theurer Cancer Center (JTCC), are part of a published Phase 3 study reporting on the equival

Updated on: March 21,2024 15

New research finds oral leukemia therapy to work as well as intravenous decitabine

by Hackensack Meridian HealthCredit: Pixabay/CC0 Public DomainResearchers at Hackensack Meridian's John Theurer Cancer Center (JTCC), are part of a published Phase 3 study reporting on the equival

Updated on:March 21,2024 15

Trial results support 'new gold standard' for head and neck cancer radiotherapy

byInstitute of Cancer ResearchRadiotherapy IMRT. Credit: Jan Chlebik/the ICRPhase III trial results on a precision radiotherapy technique support a "new gold standard" for treating hea

Updated on: January 04,2024 18

Trial results support 'new gold standard' for head and neck cancer radiotherapy

byInstitute of Cancer ResearchRadiotherapy IMRT. Credit: Jan Chlebik/the ICRPhase III trial results on a precision radiotherapy technique support a "new gold standard" for treating hea

Updated on:January 04,2024 18

Cancer cells adopt hitherto unknown state to facilitate metastasis

by Susann Huster,Leipzig UniversityCredit: Pixabay/CC0 Public DomainThe ancient Egyptians, as described in the Ebers Papyrus, already knew that palpation—feeling for hardened lumps—can help diag

Updated on: December 18,2023 12

Cancer cells adopt hitherto unknown state to facilitate metastasis

by Susann Huster,Leipzig UniversityCredit: Pixabay/CC0 Public DomainThe ancient Egyptians, as described in the Ebers Papyrus, already knew that palpation—feeling for hardened lumps—can help diag

Updated on:December 18,2023 12