The way genes are switched on in one-cell embryos may resemble the trigger for cancer

byUniversity of BathGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112023When an embryo is formed, its genes—donated by a fertilizing sperm and egg—are sil

Updated on: December 25,2023 9

The way genes are switched on in one-cell embryos may resemble the trigger for cancer

byUniversity of BathGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112023When an embryo is formed, its genes—donated by a fertilizing sperm and egg—are sil

Updated on:December 25,2023 9

Using spatial single-cell transcriptomics to visualize diffuse midline glioma

byChildren's Hospital BostonH3-K27M DMG cohort profiled by single-cell multi-omics. a, Schematic of the workflow. b, Clinico-molecular cohort characteristics. The upper legend bars depict th

Updated on: December 28,2023 13

Using spatial single-cell transcriptomics to visualize diffuse midline glioma

byChildren's Hospital BostonH3-K27M DMG cohort profiled by single-cell multi-omics. a, Schematic of the workflow. b, Clinico-molecular cohort characteristics. The upper legend bars depict th

Updated on:December 28,2023 13

Novel treatment shows promise against rare cancer in kids

by Carla K. JohnsonThis December 1993 microscope photo provided by the National Cancer Institute shows a typical neuroblastoma with rosette formation. In a study published Wednesday, April 5, 2023, in

Updated on: March 25,2024 12

Novel treatment shows promise against rare cancer in kids

by Carla K. JohnsonThis December 1993 microscope photo provided by the National Cancer Institute shows a typical neuroblastoma with rosette formation. In a study published Wednesday, April 5, 2023, in

Updated on:March 25,2024 12

Scientists develop DNA molecule that may one day be used as 'vaccine' for prostate cancer

by City of HopeDNA drug (CpG-STAT3 antisense, red) is penetrating human prostate cancer cells within 15 minutes of exposure (CpG-STAT3 antisense, red; intracellular vesicles, green). Credit: City of H

Updated on: December 18,2023 20

Scientists develop DNA molecule that may one day be used as 'vaccine' for prostate cancer

by City of HopeDNA drug (CpG-STAT3 antisense, red) is penetrating human prostate cancer cells within 15 minutes of exposure (CpG-STAT3 antisense, red; intracellular vesicles, green). Credit: City of H

Updated on:December 18,2023 20

WHO agency says talc is 'probably' cancer-causing

Johnson & Johnson removed its baby powder from the North American market in 2020 after talc came under greater scrutiny for causing cancer.The World Health Organization's cancer agency on Frid

Updated on: July 06,2024 0

WHO agency says talc is 'probably' cancer-causing

Johnson & Johnson removed its baby powder from the North American market in 2020 after talc came under greater scrutiny for causing cancer.The World Health Organization's cancer agency on Frid

Updated on:July 06,2024 0

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on: April 27,2024 0

Researchers identify new genetic risk factors for persistent HPV infections

byUniversity of Maryland School of MedicineDistribution of binding affinity IC50 values by HLA-DRB1 allele category (A) all binding predictions (B) Excluding non-binders (lC50 > 5000 nM). Cre

Updated on:April 27,2024 0

Researchers shed light on cancer drug resistance, potential to expand use of PARP inhibitors across cancer types

byThe University of Hong KongInactivation of a DNA repair gene called FANCM enhances the formation of DNA damage and chromosomal instability induced by a PARP inhibitor, leading to massive cance

Updated on: August 27,2024 0

Researchers shed light on cancer drug resistance, potential to expand use of PARP inhibitors across cancer types

byThe University of Hong KongInactivation of a DNA repair gene called FANCM enhances the formation of DNA damage and chromosomal instability induced by a PARP inhibitor, leading to massive cance

Updated on:August 27,2024 0

Gene interactions classify bowel tumors for personalized medicine

byeLifeFlowchart of the interaction-perturbation-based program. As an example, the background network consists of six genes and five interactions. There were three normal samples (yellow) and th

Updated on: December 25,2023 9

Gene interactions classify bowel tumors for personalized medicine

byeLifeFlowchart of the interaction-perturbation-based program. As an example, the background network consists of six genes and five interactions. There were three normal samples (yellow) and th

Updated on:December 25,2023 9

Breast density notification laws not effective for all women

byYale UniversityA new study suggests that state-mandated notifications on mammogram reports intended to inform women of the health risks related to breast density are not worded effectively.The

Updated on: December 20,2023 21

Breast density notification laws not effective for all women

byYale UniversityA new study suggests that state-mandated notifications on mammogram reports intended to inform women of the health risks related to breast density are not worded effectively.The

Updated on:December 20,2023 21

Enhanced tumor modeling using Laponite bioinks for 3D bioprinting

by Terasaki Institute for Biomedical InnovationScientists from the Terasaki Institute for Biomedical Innovation (TIBI) have formulated a tuneable, nanoengineered bioink for tumor modeling which contai

Updated on: January 04,2024 8

Enhanced tumor modeling using Laponite bioinks for 3D bioprinting

by Terasaki Institute for Biomedical InnovationScientists from the Terasaki Institute for Biomedical Innovation (TIBI) have formulated a tuneable, nanoengineered bioink for tumor modeling which contai

Updated on:January 04,2024 8

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on: January 04,2024 13

Skin cancer: New therapy option to prevent metastases

byMedical University of ViennaA, Invadopodia index of MMPi treated wells normalized to DMSO control in 3 independent screening plates as indicated; B, MTS signal values of B16-F10 and WM983C cel

Updated on:January 04,2024 13

Lower prostate cancer screening rates associated with subsequent increase in advanced cancers

byAmerican Society for Radiation OncologyProstate cancer cells. Credit: NIH Image GalleryIn the face of conflicting evidence over the risks and benefits of routine prostate cancer screenings, a

Updated on: December 26,2023 12

Lower prostate cancer screening rates associated with subsequent increase in advanced cancers

byAmerican Society for Radiation OncologyProstate cancer cells. Credit: NIH Image GalleryIn the face of conflicting evidence over the risks and benefits of routine prostate cancer screenings, a

Updated on:December 26,2023 12