KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MDPrithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal tr

Updated on: October 24,2023 23

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MDPrithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal tr

Updated on:October 24,2023 23

Study reviews the role of a ribonucleic acid 'MALAT1' in hematological malignancies

by Cactus CommunicationsRecent studies have shown that an abnormally high expression of MALAT1 in blood cancer cells could aid the chemotherapeutic resistance development through multiple intermolecul

Updated on: April 28,2024 0

Study reviews the role of a ribonucleic acid 'MALAT1' in hematological malignancies

by Cactus CommunicationsRecent studies have shown that an abnormally high expression of MALAT1 in blood cancer cells could aid the chemotherapeutic resistance development through multiple intermolecul

Updated on:April 28,2024 0

Breakaway breast cancer cells can travel to the brain: Scientists plot path in quest to block entry

by Delthia Ricks , Medical XpressIn vitro characterization of in vivo / ex vivo-derived 4T1 metastatic cell lines. (A) Schematic representation of the procedure used to generate the 4T1-BM2 metastatic

Updated on: December 22,2023 9

Breakaway breast cancer cells can travel to the brain: Scientists plot path in quest to block entry

by Delthia Ricks , Medical XpressIn vitro characterization of in vivo / ex vivo-derived 4T1 metastatic cell lines. (A) Schematic representation of the procedure used to generate the 4T1-BM2 metastatic

Updated on:December 22,2023 9

Three-drug combination therapy effective in patients with high-risk chronic lymphocytic leukemia, trial shows

byDana-Farber Cancer InstituteNew research shows that genetics account for only five to 10 per cent of risk for most human diseases, and that gene testing is a poor predictor of whether someone

Updated on: January 04,2024 9

Three-drug combination therapy effective in patients with high-risk chronic lymphocytic leukemia, trial shows

byDana-Farber Cancer InstituteNew research shows that genetics account for only five to 10 per cent of risk for most human diseases, and that gene testing is a poor predictor of whether someone

Updated on:January 04,2024 9

Relapse Following CAR T-cell Therapy Linked to Poor OS in Relapsed/Refractory Myeloma

August 27, 2022Lisa AstorRelapse following treatment with BCMA-directed CAR T-cell therapy was associated with poor survival outcomes in patients with relapsed/refractory multiple myeloma.Multiple Mye

Updated on: October 24,2023 31

Relapse Following CAR T-cell Therapy Linked to Poor OS in Relapsed/Refractory Myeloma

August 27, 2022Lisa AstorRelapse following treatment with BCMA-directed CAR T-cell therapy was associated with poor survival outcomes in patients with relapsed/refractory multiple myeloma.Multiple Mye

Updated on:October 24,2023 31

Routine HPV testing may be warranted for sinonasal cancers

(HealthDay)—Only one in four patients with sinonasal squamous cell carcinoma (SNSCC) is tested for human papillomavirus (HPV), according to a study published online Dec. 30 inCancer.Jamie R. Oli

Updated on: December 20,2023 14

Routine HPV testing may be warranted for sinonasal cancers

(HealthDay)—Only one in four patients with sinonasal squamous cell carcinoma (SNSCC) is tested for human papillomavirus (HPV), according to a study published online Dec. 30 inCancer.Jamie R. Oli

Updated on:December 20,2023 14

MRD Could Play Role in Predicting Post-ASCT Outcomes in Myeloma

September 9, 2021Darlene Dobkowski, MAFor patients with myeloma have undergone an autologous stem cell transplant and are currently on maintenance therapy with lenalidomide, minimal residual disease m

Updated on: October 24,2023 6

MRD Could Play Role in Predicting Post-ASCT Outcomes in Myeloma

September 9, 2021Darlene Dobkowski, MAFor patients with myeloma have undergone an autologous stem cell transplant and are currently on maintenance therapy with lenalidomide, minimal residual disease m

Updated on:October 24,2023 6

Measuring changes in brain tissue oxygenation for personalized cancer radiotherapy

bySPIEResearchers used a functional near-infrared spectroscopy (fNIRS) device attached to the patient's forehead to measure changes in hemoglobin and tissue oxygenation levels. The device wa

Updated on: December 19,2023 12

Measuring changes in brain tissue oxygenation for personalized cancer radiotherapy

bySPIEResearchers used a functional near-infrared spectroscopy (fNIRS) device attached to the patient's forehead to measure changes in hemoglobin and tissue oxygenation levels. The device wa

Updated on:December 19,2023 12

Using SPEDOX-6 to provide targeted cancer treatment and protect heart cells

by International Society for Stem Cell ResearchSPEDOX-6 causes less damage to heart cells than dox. Left: stem cell derived heart cells treated with dox. Right: stem cell derived heart cells treated w

Updated on: January 04,2024 16

Using SPEDOX-6 to provide targeted cancer treatment and protect heart cells

by International Society for Stem Cell ResearchSPEDOX-6 causes less damage to heart cells than dox. Left: stem cell derived heart cells treated with dox. Right: stem cell derived heart cells treated w

Updated on:January 04,2024 16

Looking at the role epigenetics plays in the ways cancer behaves

by Bob Yirka , Medical XpressGenetic control of expression with eQTL. a, The number of genes with significant models for each data type. b, Distribution of regression coefficients (effect sizes) for e

Updated on: December 27,2023 12

Looking at the role epigenetics plays in the ways cancer behaves

by Bob Yirka , Medical XpressGenetic control of expression with eQTL. a, The number of genes with significant models for each data type. b, Distribution of regression coefficients (effect sizes) for e

Updated on:December 27,2023 12

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often

Updated on: March 12,2024 10

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often

Updated on:March 12,2024 10

Breaking down proteins: How starving cancer cells switch food sources

byGerman Cancer Research CenterHuman cancer cells (cell nucleus in blue) feeding on protein (Albumin, labeled in green). The proteins are digested and broken down into amino acids in the lysosom

Updated on: December 22,2023 13

Breaking down proteins: How starving cancer cells switch food sources

byGerman Cancer Research CenterHuman cancer cells (cell nucleus in blue) feeding on protein (Albumin, labeled in green). The proteins are digested and broken down into amino acids in the lysosom

Updated on:December 22,2023 13