Study identifies promising target for treating inflammatory bowel disease and colitis-induced colorectal cancers

by Will Cushman,University of Wisconsin-MadisonThis image shows the effect of pro-inflammatory cytokines on the growth of a mouse intestinal organoid. Intestinal stem cells (red) are indicative

Updated on: March 20,2024 13

Study identifies promising target for treating inflammatory bowel disease and colitis-induced colorectal cancers

by Will Cushman,University of Wisconsin-MadisonThis image shows the effect of pro-inflammatory cytokines on the growth of a mouse intestinal organoid. Intestinal stem cells (red) are indicative

Updated on:March 20,2024 13

Racial disparity in pro-metastatic tumor microenvironment among women with residual breast cancer after NAC

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainResidual tumors from Black patients with estrogen receptor (ER)-positive/HER2-negative primary breast cancer treated w

Updated on: December 17,2023 10

Racial disparity in pro-metastatic tumor microenvironment among women with residual breast cancer after NAC

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainResidual tumors from Black patients with estrogen receptor (ER)-positive/HER2-negative primary breast cancer treated w

Updated on:December 17,2023 10

Low income linked to high recurrence risk, poorer survival in women with ER-positive breast cancer

by Roswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainPatients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to hav

Updated on: December 20,2023 10

Low income linked to high recurrence risk, poorer survival in women with ER-positive breast cancer

by Roswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainPatients with early-stage estrogen receptor-positive breast cancer who live in low-income neighborhoods are likelier to hav

Updated on:December 20,2023 10

Online testing tool identifies people likely to benefit from genetic testing for inherited risk for certain cancers

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainAn online tool developed by researchers and physicians at Dana-Farber Cancer Institute can accurately and rapidly identify people

Updated on: December 18,2023 24

Online testing tool identifies people likely to benefit from genetic testing for inherited risk for certain cancers

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainAn online tool developed by researchers and physicians at Dana-Farber Cancer Institute can accurately and rapidly identify people

Updated on:December 18,2023 24

Breast cancer patients to be evaluated for genetic testing

byVanderbilt University Medical CenterCredit: CC0 Public DomainAccording to a statement on behalf of the American College of Medical Genetics and Genomics (ACMG) published Dec. 13 in the organiz

Updated on: December 22,2023 24

Breast cancer patients to be evaluated for genetic testing

byVanderbilt University Medical CenterCredit: CC0 Public DomainAccording to a statement on behalf of the American College of Medical Genetics and Genomics (ACMG) published Dec. 13 in the organiz

Updated on:December 22,2023 24

Vitamin B6, leukemia's deadly addiction

by Brian Stallard,Cold Spring Harbor LaboratoryThe PDXK enzyme manages the activity of B6, activating it when it is time for cells to divide. In AML, cancerous cells (green) can take advantage o

Updated on: December 22,2023 22

Vitamin B6, leukemia's deadly addiction

by Brian Stallard,Cold Spring Harbor LaboratoryThe PDXK enzyme manages the activity of B6, activating it when it is time for cells to divide. In AML, cancerous cells (green) can take advantage o

Updated on:December 22,2023 22

Single-cell 'atlas' reveals origin of an aggressive brain tumor

byCincinnati Children's Hospital Medical CenterChartshows that mice with reduced activity of either the SOX11 or HNRNOH1 genes had longer survival times when induced to develop medullo

Updated on: December 20,2023 10

Single-cell 'atlas' reveals origin of an aggressive brain tumor

byCincinnati Children's Hospital Medical CenterChartshows that mice with reduced activity of either the SOX11 or HNRNOH1 genes had longer survival times when induced to develop medullo

Updated on:December 20,2023 10

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on: December 22,2023 22

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on:December 22,2023 22

Developing therapies for treatment-resistant prostate cancer: Small clinical trial shows 40% progression-free survival

byCedars-Sinai Medical CenterGraphical abstract. Credit:Molecular Therapy(2022). DOI: 10.1016/j.ymthe.2022.08.019Investigators from Cedars-Sinai Cancer have identified an investigati

Updated on: December 26,2023 6

Developing therapies for treatment-resistant prostate cancer: Small clinical trial shows 40% progression-free survival

byCedars-Sinai Medical CenterGraphical abstract. Credit:Molecular Therapy(2022). DOI: 10.1016/j.ymthe.2022.08.019Investigators from Cedars-Sinai Cancer have identified an investigati

Updated on:December 26,2023 6

Pregnancy possible after chemotherapy for breast cancer patients, but many no longer wish

byEuropean Society for Medical OncologyDr. Jérôme Martin-Babau from Centre Armoricain de Radiothérapie, Imagerie Médicale et Oncologie in Plérin, France, study author. Credit: European Society f

Updated on: December 18,2023 11

Pregnancy possible after chemotherapy for breast cancer patients, but many no longer wish

byEuropean Society for Medical OncologyDr. Jérôme Martin-Babau from Centre Armoricain de Radiothérapie, Imagerie Médicale et Oncologie in Plérin, France, study author. Credit: European Society f

Updated on:December 18,2023 11

AI can be used to detect and grade prostate cancer

byKarolinska InstitutetMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Researchers at Karolinska Institutet in Sw

Updated on: December 22,2023 10

AI can be used to detect and grade prostate cancer

byKarolinska InstitutetMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Researchers at Karolinska Institutet in Sw

Updated on:December 22,2023 10

Incidence of early-onset gastric cancer increasing in the U.S.

(HealthDay)—The incidence of early-onset gastric cancer has been increasing in the United States, and it seems to be distinct clinically and genetically from late-onset gastric cancer, according to a

Updated on: December 22,2023 15

Incidence of early-onset gastric cancer increasing in the U.S.

(HealthDay)—The incidence of early-onset gastric cancer has been increasing in the United States, and it seems to be distinct clinically and genetically from late-onset gastric cancer, according to a

Updated on:December 22,2023 15