RXR, the cell protein that keeps blood stem cells young and fit

RXR, the cell protein that keeps blood stem cells young and fitby Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Bone marrow histology in a normal mouse and in a mouse lacking

Updated on: October 29,2023 10

RXR, the cell protein that keeps blood stem cells young and fit

RXR, the cell protein that keeps blood stem cells young and fitby Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Bone marrow histology in a normal mouse and in a mouse lacking

Updated on:October 29,2023 10

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on: December 22,2023 9

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on:December 22,2023 9

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house

Updated on: December 22,2023 9

Faster genomics-based diagnosis may accelerate targeted treatment of patients with myeloid neoplasms

byElsevierA: Comparison of clinical assay variant allele fraction (VAF) and Ion Torrent Genexus VAF showed high correlation (r2= 0.98) across a broad range of VAFs, including both in-house

Updated on:December 22,2023 9

First genomic study of puberty yields insights into development and cancer

by Huntsman Cancer InstituteBradley Cairns, Ph.D. Credit: Huntsman Cancer InstituteIn the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (H

Updated on: December 20,2023 19

First genomic study of puberty yields insights into development and cancer

by Huntsman Cancer InstituteBradley Cairns, Ph.D. Credit: Huntsman Cancer InstituteIn the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (H

Updated on:December 20,2023 19

Gut microbiome can play key role in response to CAR-T cell cancer immunotherapy

byGerman Cancer Research CenterCredit: Unsplash/CC0 Public DomainScientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the U.S., have found tha

Updated on: December 19,2023 10

Gut microbiome can play key role in response to CAR-T cell cancer immunotherapy

byGerman Cancer Research CenterCredit: Unsplash/CC0 Public DomainScientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the U.S., have found tha

Updated on:December 19,2023 10

Distinguishing fatal prostate cancer from 'manageable' cancer now possible

byUniversity of YorkScientists at the University of York have found a way of distinguishing between fatal prostate cancer and manageable cancer, which could reduce unnecessary surgeries and radi

Updated on: December 18,2023 13

Distinguishing fatal prostate cancer from 'manageable' cancer now possible

byUniversity of YorkScientists at the University of York have found a way of distinguishing between fatal prostate cancer and manageable cancer, which could reduce unnecessary surgeries and radi

Updated on:December 18,2023 13

Affordable Care Act led to improved treatment of colorectal cancer among young adults

byAmerican Cancer SocietyCredit: CC0 Public DomainAn Affordable Care Act provision that allowed young adults to be covered under their parents' insurance led to a shift to earlier-stage diag

Updated on: December 22,2023 15

Affordable Care Act led to improved treatment of colorectal cancer among young adults

byAmerican Cancer SocietyCredit: CC0 Public DomainAn Affordable Care Act provision that allowed young adults to be covered under their parents' insurance led to a shift to earlier-stage diag

Updated on:December 22,2023 15

For some small kidney cancers, freezing is more effective than heat treatment

byWolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with early-stage renal cell carcinomas (RCCs) that measure between 3 and 4 centimeters, a procedure that destroys the cancer

Updated on: December 21,2023 10

For some small kidney cancers, freezing is more effective than heat treatment

byWolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with early-stage renal cell carcinomas (RCCs) that measure between 3 and 4 centimeters, a procedure that destroys the cancer

Updated on:December 21,2023 10

Is the next big step in cancer therapy personalized vaccines?

byUniversity of California - San DiegoEzra Cohen, MD, UC San Diego Health physician scientist, administered the first-of-its-kind personalized cancer vaccine to Tamara Strauss, while Aaron Mille

Updated on: December 18,2023 19

Is the next big step in cancer therapy personalized vaccines?

byUniversity of California - San DiegoEzra Cohen, MD, UC San Diego Health physician scientist, administered the first-of-its-kind personalized cancer vaccine to Tamara Strauss, while Aaron Mille

Updated on:December 18,2023 19

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on: December 26,2023 10

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on:December 26,2023 10

Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in some breast cancer

byScience China PressThe CDK4/6 inhibitors-resistant breast cancer cells expressed more Cyclin D1 and CDK4 proteins than the parental cells (Upper left). PI3K pathway was hyper-activated in the

Updated on: December 23,2023 16

Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in some breast cancer

byScience China PressThe CDK4/6 inhibitors-resistant breast cancer cells expressed more Cyclin D1 and CDK4 proteins than the parental cells (Upper left). PI3K pathway was hyper-activated in the

Updated on:December 23,2023 16

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on: December 21,2023 13

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on:December 21,2023 13