First test of anti-cancer agent PAC-1 in human clinical trials shows promise

by Diana Yates,University of Illinois at Urbana-ChampaignProcaspase-3 (PC-3) expressions in diverse tumor histologies categorized as moderate-to-strong immunostaining intensities. Credit:B

Updated on: December 27,2023 6

First test of anti-cancer agent PAC-1 in human clinical trials shows promise

by Diana Yates,University of Illinois at Urbana-ChampaignProcaspase-3 (PC-3) expressions in diverse tumor histologies categorized as moderate-to-strong immunostaining intensities. Credit:B

Updated on:December 27,2023 6

Localizing BRCA gene mutations to better treat ovarian cancer

byUniversity of GenevaDistribution of mutations in BRCA1 and BRCA2. A. Graphical summary of BRCA1 and BRCA2 mutations. Mutation plot was generated using cBioPortal MutationMapper tool. Black = n

Updated on: December 20,2023 10

Localizing BRCA gene mutations to better treat ovarian cancer

byUniversity of GenevaDistribution of mutations in BRCA1 and BRCA2. A. Graphical summary of BRCA1 and BRCA2 mutations. Mutation plot was generated using cBioPortal MutationMapper tool. Black = n

Updated on:December 20,2023 10

Online educational videos boost cancer knowledge

byRutgers UniversityCredit: CC0 Public DomainOnline health videos can be an important source of cancer education, according to Rutgers researchers. Their review, published in theJournal of

Updated on: December 20,2023 25

Online educational videos boost cancer knowledge

byRutgers UniversityCredit: CC0 Public DomainOnline health videos can be an important source of cancer education, according to Rutgers researchers. Their review, published in theJournal of

Updated on:December 20,2023 25

Cancer Gene Census paves the way for improvements in personalised medicine

byWellcome Trust Sanger InstituteCredit: Wellcome Trust Sanger InstituteResearchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involve

Updated on: December 18,2023 16

Cancer Gene Census paves the way for improvements in personalised medicine

byWellcome Trust Sanger InstituteCredit: Wellcome Trust Sanger InstituteResearchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involve

Updated on:December 18,2023 16

Scientists develop a cancer vaccine to simultaneously kill and prevent brain cancer

byBrigham and Women's HospitalScientists developed a bifunctional therapeutic strategy by transforming living tumor cells into a therapeutic. Shah’s team engineered living tumor cells using

Updated on: December 27,2023 6

Scientists develop a cancer vaccine to simultaneously kill and prevent brain cancer

byBrigham and Women's HospitalScientists developed a bifunctional therapeutic strategy by transforming living tumor cells into a therapeutic. Shah’s team engineered living tumor cells using

Updated on:December 27,2023 6

Symptom self-monitoring for childhood cancer survivors—what are oncologists' views?

byKing's College LondonCredit: Unsplash/CC0 Public DomainA new international survey, led by the Stanford University Department of Anesthesiology, Perioperative, and Pain Medicine, and the In

Updated on: December 21,2023 10

Symptom self-monitoring for childhood cancer survivors—what are oncologists' views?

byKing's College LondonCredit: Unsplash/CC0 Public DomainA new international survey, led by the Stanford University Department of Anesthesiology, Perioperative, and Pain Medicine, and the In

Updated on:December 21,2023 10

Selpercatinib Significantly Improves PFS, Responses in Advanced RET+ Medullary Thyroid Cancer

October 21, 2023Gina MauroSelpercatinib resulted in a statistically significant improvement in progression-free survival and overall response rate compared with cabozantinib or vandetanib in patients

Updated on: October 24,2023 2

Selpercatinib Significantly Improves PFS, Responses in Advanced RET+ Medullary Thyroid Cancer

October 21, 2023Gina MauroSelpercatinib resulted in a statistically significant improvement in progression-free survival and overall response rate compared with cabozantinib or vandetanib in patients

Updated on:October 24,2023 2

Gallbladder and bile duct cancers: Rare, silent and deadly. Know the signs

by Cara MurezBile duct and gallbladder cancers develop in organs deep inside the body, making them difficult to detect.Knowing the signs of these rare cancers may help with earlier detection.Gallbladd

Updated on: December 20,2023 10

Gallbladder and bile duct cancers: Rare, silent and deadly. Know the signs

by Cara MurezBile duct and gallbladder cancers develop in organs deep inside the body, making them difficult to detect.Knowing the signs of these rare cancers may help with earlier detection.Gallbladd

Updated on:December 20,2023 10

Pembrolizumab Monotherapy Displays Efficacy in Rare Sarcomas

The PD-1 inhibitor pembrolizumab (Keytruda) displayed activity with a manageable safety profile in patients with certain rare and ultra-raresarcoma histotypes, according to findings from the phase 2 A

Updated on: November 07,2023 6

Pembrolizumab Monotherapy Displays Efficacy in Rare Sarcomas

The PD-1 inhibitor pembrolizumab (Keytruda) displayed activity with a manageable safety profile in patients with certain rare and ultra-raresarcoma histotypes, according to findings from the phase 2 A

Updated on:November 07,2023 6

Estrogen Receptor Mutation Prospects in Endometrial Cancer Treatment

byHemalatha Manikandanon August 22, 2023Inhibiting CDK9, a protein that works withestrogen receptors, was effective at minimizing the proliferation ofendometrial cancerce

Updated on: December 19,2023 32

Estrogen Receptor Mutation Prospects in Endometrial Cancer Treatment

byHemalatha Manikandanon August 22, 2023Inhibiting CDK9, a protein that works withestrogen receptors, was effective at minimizing the proliferation ofendometrial cancerce

Updated on:December 19,2023 32

Noninvasive Test Shows Promise in Early Bladder Cancer Diagnosis

byColleen Fleisson August 15, 2023A new molecular diagnostic method that identifies primary bladder cancer in patients who observe blood in their urine (hematuria) could expediteblad

Updated on: December 19,2023 23

Noninvasive Test Shows Promise in Early Bladder Cancer Diagnosis

byColleen Fleisson August 15, 2023A new molecular diagnostic method that identifies primary bladder cancer in patients who observe blood in their urine (hematuria) could expediteblad

Updated on:December 19,2023 23

Making glioblastoma more vulnerable to treatment

byMedical College of Georgia at Augusta UniversityDr. Waaqo Daddacha. Credit: Michael Holahan, Augusta UniversityIn the tough war against glioblastoma, scientists are taking a cue from viruses o

Updated on: January 04,2024 9

Making glioblastoma more vulnerable to treatment

byMedical College of Georgia at Augusta UniversityDr. Waaqo Daddacha. Credit: Michael Holahan, Augusta UniversityIn the tough war against glioblastoma, scientists are taking a cue from viruses o

Updated on:January 04,2024 9