Scientists identify gene target to boost effectiveness of cancer immunotherapy

by Katie Marquedant,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainImmune checkpoint inhibitors are important medications that boost the immune system's response against vari

Updated on: December 27,2023 9

Scientists identify gene target to boost effectiveness of cancer immunotherapy

by Katie Marquedant,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainImmune checkpoint inhibitors are important medications that boost the immune system's response against vari

Updated on:December 27,2023 9

The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

byThe Spanish National Cancer Research CentreRAF1. Credit: CNIOOne of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer

Updated on: December 20,2023 10

The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

byThe Spanish National Cancer Research CentreRAF1. Credit: CNIOOne of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer

Updated on:December 20,2023 10

After Pembrolizumab/Lenvatinab Provides Clinical Benefit in Previously Treated Endometrial Cancer

October 23, 2023Dylann Cohn-EmeryContinued treatment with lenvatinib monotherapy after the completeion of combination therapy with pembrolizumab and lenvatinib resulted in sustained clinical benefit v

Updated on: October 24,2023 4

After Pembrolizumab/Lenvatinab Provides Clinical Benefit in Previously Treated Endometrial Cancer

October 23, 2023Dylann Cohn-EmeryContinued treatment with lenvatinib monotherapy after the completeion of combination therapy with pembrolizumab and lenvatinib resulted in sustained clinical benefit v

Updated on:October 24,2023 4

Multi-center study sheds light on understudied breast cancer type

byUniversity of PittsburghCredit: Pixabay/CC0 Public DomainA multi-center analysis of patients with invasive lobular carcinoma, or ILC—the second most common histological subtype of invasive bre

Updated on: December 21,2023 8

Multi-center study sheds light on understudied breast cancer type

byUniversity of PittsburghCredit: Pixabay/CC0 Public DomainA multi-center analysis of patients with invasive lobular carcinoma, or ILC—the second most common histological subtype of invasive bre

Updated on:December 21,2023 8

HER2+ early breast cancers where shorter-course trastuzumab could be an option

byEuropean Society for Medical OncologyCredit: European Society for Medical OncologyWomen with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower r

Updated on: December 18,2023 17

HER2+ early breast cancers where shorter-course trastuzumab could be an option

byEuropean Society for Medical OncologyCredit: European Society for Medical OncologyWomen with HER2-positive early breast cancer with small tumours have similar disease-free survival and lower r

Updated on:December 18,2023 17

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

byGeorgetown University Medical CenterCredit: Unsplash/CC0 Public DomainWhile it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developin

Updated on: December 19,2023 10

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

byGeorgetown University Medical CenterCredit: Unsplash/CC0 Public DomainWhile it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developin

Updated on:December 19,2023 10

Scientists develop new ultrasound technique for earlier detection and diagnosis of breast cancer

byNational Physical LaboratoryCredit: Unsplash/CC0 Public DomainScientists at the UK's National Physical Laboratory (NPL) have demonstrated the first in-person measurements of breast tissue

Updated on: December 27,2023 10

Scientists develop new ultrasound technique for earlier detection and diagnosis of breast cancer

byNational Physical LaboratoryCredit: Unsplash/CC0 Public DomainScientists at the UK's National Physical Laboratory (NPL) have demonstrated the first in-person measurements of breast tissue

Updated on:December 27,2023 10

New classification system for tumors can guide diagnosis and treatment options for cancer

by Center for Genomic RegulationCredit: CC0 Public DomainBased on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumours. Clinicians can use genome

Updated on: December 22,2023 18

New classification system for tumors can guide diagnosis and treatment options for cancer

by Center for Genomic RegulationCredit: CC0 Public DomainBased on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumours. Clinicians can use genome

Updated on:December 22,2023 18

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on: December 21,2023 7

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on:December 21,2023 7

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet

Updated on: October 30,2023 29

hematopoietic changes on colon cancer, unveiling therapeutic avenues

In a recent study published in theJournal of Experimental Medicine, researchers investigated whether bone marrow-derived cells with heterozygous loss of Dnmt3a (Dnmt3a+/Δ), the most common genet

Updated on:October 30,2023 29

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

In a study published inCancer Discovery, researchers from Canada tested the use of a multimodal liquid biopsy assay based on cell-free DNA (cfDNA) for early cancer detection in patients with Li-

Updated on: October 30,2023 22

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

In a study published inCancer Discovery, researchers from Canada tested the use of a multimodal liquid biopsy assay based on cell-free DNA (cfDNA) for early cancer detection in patients with Li-

Updated on:October 30,2023 22

Acute myeloid leukemia: Germany-wide clinical trial challenges international standard of care

by Nina Louis, Medizin & WissenschaftCredit:Blood(2022). DOI: 10.1182/blood-2022-159962Prior to allogeneic stem cell transplantation for the treatment of acute myeloid leukemia (AML),

Updated on: December 25,2023 15

Acute myeloid leukemia: Germany-wide clinical trial challenges international standard of care

by Nina Louis, Medizin & WissenschaftCredit:Blood(2022). DOI: 10.1182/blood-2022-159962Prior to allogeneic stem cell transplantation for the treatment of acute myeloid leukemia (AML),

Updated on:December 25,2023 15