Tumor Profiling Studies Illuminate Nuances Across Malignancies

November 21, 2022Megan HollaschMolecular and immune landscapes for solid tumors are constantly evolving as precision medicine techniques become more sensitive and next-generation sequencing methods ar

Updated on: October 17,2023 205

Tumor Profiling Studies Illuminate Nuances Across Malignancies

November 21, 2022Megan HollaschMolecular and immune landscapes for solid tumors are constantly evolving as precision medicine techniques become more sensitive and next-generation sequencing methods ar

Updated on:October 17,2023 205

Novel risk score for cardiovascular complications after bone marrow transplant

by Noah Fromson,University of Michigan3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHFor thousands of Americans each year, a bone marrow transplant has the potential to cure diseases s

Updated on: March 20,2024 12

Novel risk score for cardiovascular complications after bone marrow transplant

by Noah Fromson,University of Michigan3D Model of the heart by Dr. Matthew Bramlet. Credit: NIHFor thousands of Americans each year, a bone marrow transplant has the potential to cure diseases s

Updated on:March 20,2024 12

Potential new treatment for angioimmunoblastic T-cell lymphoma

byUniversity of TsukubaCredit: AI-generated imageA type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from

Updated on: December 18,2023 11

Potential new treatment for angioimmunoblastic T-cell lymphoma

byUniversity of TsukubaCredit: AI-generated imageA type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from

Updated on:December 18,2023 11

Targeting enzyme could alleviate muscle wasting for cancer patients

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainTargeting a specific enzyme in the muscle could help cancer patients preserve muscle mass and potentially p

Updated on: December 19,2023 8

Targeting enzyme could alleviate muscle wasting for cancer patients

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainTargeting a specific enzyme in the muscle could help cancer patients preserve muscle mass and potentially p

Updated on:December 19,2023 8

Pioneering mRNA-4157 Cancer Vaccines: Personalized Immunotherapy for Targeted Treatment

Updated on: June 13,2024 1

Pioneering mRNA-4157 Cancer Vaccines: Personalized Immunotherapy for Targeted Treatment

Updated on:June 13,2024 1

Pembrolizumab Active in Advanced Nasopharyngeal Carcinoma

August 29, 2017Jason HarrisPembrolizumab (Keytruda) induced an overall response rate of 25.9% and was well tolerated in patients with PD-L1–positive recurrent or metastatic nasopharyngeal carcinoma.Na

Updated on: October 24,2023 76

Pembrolizumab Active in Advanced Nasopharyngeal Carcinoma

August 29, 2017Jason HarrisPembrolizumab (Keytruda) induced an overall response rate of 25.9% and was well tolerated in patients with PD-L1–positive recurrent or metastatic nasopharyngeal carcinoma.Na

Updated on:October 24,2023 76

Prexigebersen–Based Therapy Induces High CR/CRi Rates in Newly Diagnosed, Relapsed/Refractory AML

August 1, 2023Caroline SeymourPrexigebersen in combination with decitabine and venetoclax demonstrated potent antitumor activity when used in the treatment of patients with newly diagnosed and relapse

Updated on: October 12,2023 26

Prexigebersen–Based Therapy Induces High CR/CRi Rates in Newly Diagnosed, Relapsed/Refractory AML

August 1, 2023Caroline SeymourPrexigebersen in combination with decitabine and venetoclax demonstrated potent antitumor activity when used in the treatment of patients with newly diagnosed and relapse

Updated on:October 12,2023 26

One-cycle cisplatin seems safe for high-risk early testicular cancer

(HealthDay)—For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year m

Updated on: December 20,2023 12

One-cycle cisplatin seems safe for high-risk early testicular cancer

(HealthDay)—For high-risk stage 1 nonseminoma germ cell tumors of the testis (NSGCTT), one cycle of adjuvant bleomycin, etoposide (500 mg/m²), and cisplatin (BE500P) is safe, resulting in a two-year m

Updated on:December 20,2023 12

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,

Updated on: December 21,2023 10

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,

Updated on:December 21,2023 10

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom

Updated on: October 30,2023 10

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom

Updated on:October 30,2023 10

Key genetic code change drives common lung cancer type

byNYU Langone HealthGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.11.015A team led by researchers at NYU Langone Health's Perlmutter Cancer Center has i

Updated on: December 22,2023 9

Key genetic code change drives common lung cancer type

byNYU Langone HealthGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.11.015A team led by researchers at NYU Langone Health's Perlmutter Cancer Center has i

Updated on:December 22,2023 9

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

At the 2023 American Society for Clinical Oncology Annual Meeting—to be held June 2-6 in Chicago, Illinois—Fred Hutchinson Cancer Center experts will present research spanning survivorship, advances i

Updated on: November 21,2023 17

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

At the 2023 American Society for Clinical Oncology Annual Meeting—to be held June 2-6 in Chicago, Illinois—Fred Hutchinson Cancer Center experts will present research spanning survivorship, advances i

Updated on:November 21,2023 17