Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on: April 09,2024 11

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on:April 09,2024 11

Multi-modal AI models for intermediate- to high-risk localized prostate cancer

by NRG OncologyCredit: Pixabay/CC0 Public DomainNRG Oncology investigators analyzed clinical and digital histopathology data from five Phase III prostate cancer trials (NRG/RTOG 9202, 9408, 9413, 9910

Updated on: January 30,2024 11

Multi-modal AI models for intermediate- to high-risk localized prostate cancer

by NRG OncologyCredit: Pixabay/CC0 Public DomainNRG Oncology investigators analyzed clinical and digital histopathology data from five Phase III prostate cancer trials (NRG/RTOG 9202, 9408, 9413, 9910

Updated on:January 30,2024 11

Researcher looks at molecular changes for clues to disparities in breast cancer outcomes

by Medical University of South CarolinaPeggi Angel, Ph.D., is in looking at how socioeconomic stressors may influence metabolic processes that could in turn create a "tumor permissive"

Updated on: February 18,2024 19

Researcher looks at molecular changes for clues to disparities in breast cancer outcomes

by Medical University of South CarolinaPeggi Angel, Ph.D., is in looking at how socioeconomic stressors may influence metabolic processes that could in turn create a "tumor permissive"

Updated on:February 18,2024 19

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on: March 30,2024 10

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on:March 30,2024 10

Lethal brain tumour shields itself from immune attack

by Hayley Jarvis,Brunel UniversityGBM cells can be highly invasive in the brain, or fast growing while being localised. Credit: Dr SK Singh, Gottingen Medical Centre, GermanyOne of the deadliest

Updated on: March 01,2024 20

Lethal brain tumour shields itself from immune attack

by Hayley Jarvis,Brunel UniversityGBM cells can be highly invasive in the brain, or fast growing while being localised. Credit: Dr SK Singh, Gottingen Medical Centre, GermanyOne of the deadliest

Updated on:March 01,2024 20

Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho

Updated on: January 30,2024 20

Researchers identify potential biomarker to distinguish two aggressive types of brain tumors in children

by Johns Hopkins University School of MedicineSMYD3 overexpression activates the EGFR pathway in CHLA01 cells. (A) Localization of endogenous SMYD3. Representative 60x Z-stack confocal images sho

Updated on:January 30,2024 20

Genetic ancestry and social environment may influence how aggressive breast cancer is in Black women

by Rutgers Cancer Institute of New JerseyKaplan-Meier Survival Curves for All-Cause Mortality by Quartiles (Q) of African Ancestry and Neighborhood Socioeconomic Status (nSES) in 1,575 Black Women wit

Updated on: May 13,2024 6

Genetic ancestry and social environment may influence how aggressive breast cancer is in Black women

by Rutgers Cancer Institute of New JerseyKaplan-Meier Survival Curves for All-Cause Mortality by Quartiles (Q) of African Ancestry and Neighborhood Socioeconomic Status (nSES) in 1,575 Black Women wit

Updated on:May 13,2024 6

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on: January 02,2024 9

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on:January 02,2024 9

Predicting efficacy of neoadjuvant chemotherapy for advanced gastric cancer

by Zhang Nannan,Chinese Academy of SciencesProcess for predicting the NACT efficacy in AGC. Credit: SIBETGastric cancer is a common malignant tumor that originates from the gastric mucosal epith

Updated on: February 24,2024 16

Predicting efficacy of neoadjuvant chemotherapy for advanced gastric cancer

by Zhang Nannan,Chinese Academy of SciencesProcess for predicting the NACT efficacy in AGC. Credit: SIBETGastric cancer is a common malignant tumor that originates from the gastric mucosal epith

Updated on:February 24,2024 16

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on: May 13,2024 5

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on:May 13,2024 5

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on: May 21,2024 6

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on:May 21,2024 6

Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor

by St. Jude Children's Research HospitalElizabeth Stewart, M.D., and Hong Wang, Ph.D. of St. Jude Children's Research Hospital. Credit: St. Jude Children's Research HospitalSt. Jude C

Updated on: April 01,2024 16

Integrated analysis finds vulnerabilities to target in a high-risk pediatric tumor

by St. Jude Children's Research HospitalElizabeth Stewart, M.D., and Hong Wang, Ph.D. of St. Jude Children's Research Hospital. Credit: St. Jude Children's Research HospitalSt. Jude C

Updated on:April 01,2024 16