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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Nature-inspired peptide shows anti-tumor activity

Nature-inspired peptide shows anti-tumor activity

by Forschung & Bildung GmbHStructure and synthesis of kalata-type cyclotides. Pie-shaped flow chart demonstrates the solid phase peptide synthesis of kalata-type cyclotides by example of T20K. The

Nature-inspired peptide shows anti-tumor activity

by Forschung & Bildung GmbHStructure and synthesis of kalata-type cyclotides. Pie-shaped flow chart demonstrates the solid phase peptide synthesis of kalata-type cyclotides by example of T20K. The
New targets for CAR-T cell therapy against acute myeloid leukemia through AI-assisted analysis

New targets for CAR-T cell therapy against acute myeloid leukemia through AI-assisted analysis

byHelmholtz Association of German Research CentresmCSF1R CART do not cause toxicity in mice. Credit:Nature Biotechnology(2023). https://doi.org/10.1038/s41587-023-01684-0Unlike other

New targets for CAR-T cell therapy against acute myeloid leukemia through AI-assisted analysis

byHelmholtz Association of German Research CentresmCSF1R CART do not cause toxicity in mice. Credit:Nature Biotechnology(2023). https://doi.org/10.1038/s41587-023-01684-0Unlike other
Predicting condensate formation by cancer-associated fusion oncoproteins

Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar

Predicting condensate formation by cancer-associated fusion oncoproteins

bySt. Jude Children's Research HospitalOverview of the fusion oncoprotein (FO) database (FOdb). Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41655-2Many cancers ar
Blocking DNA production in cancer therapy by targeting the POLtheta enzyme

Blocking DNA production in cancer therapy by targeting the POLtheta enzyme

by Austrian Academy of SciencesGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111716BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instance

Blocking DNA production in cancer therapy by targeting the POLtheta enzyme

by Austrian Academy of SciencesGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111716BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instance
Improving CAR T-cell and monoclonal antibody treatment through epitope editing

Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t

Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t
Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f
Unique genetic signature found by research in different types of cancer

Unique genetic signature found by research in different types of cancer

by MELISA InstitutetimsTOF Pro mass spectrometer located in MELISA Institute's laboratories. Credit: MELISA InstituteResearch led by Dr. Mabel Vidal in the Department of Computer Science at the Un

Unique genetic signature found by research in different types of cancer

by MELISA InstitutetimsTOF Pro mass spectrometer located in MELISA Institute's laboratories. Credit: MELISA InstituteResearch led by Dr. Mabel Vidal in the Department of Computer Science at the Un
Optimizing tobacco cessation treatment with lung cancer screening

Optimizing tobacco cessation treatment with lung cancer screening

byUniversity of MinnesotaVisual Abstract.Optimizing Longitudinal Tobacco Cessation Treatment in Lung Cancer Screening. Credit:JAMA Network Open(2023). DOI: 10.1001/jamanetworko

Optimizing tobacco cessation treatment with lung cancer screening

byUniversity of MinnesotaVisual Abstract.Optimizing Longitudinal Tobacco Cessation Treatment in Lung Cancer Screening. Credit:JAMA Network Open(2023). DOI: 10.1001/jamanetworko
Beating cancer-related fatigue with personalized interventions

Beating cancer-related fatigue with personalized interventions

byUniversity of TwenteFlow diagram of selection of eligible studies. Credit:European Journal of Cancer Care(2022). DOI: 10.1111/ecc.13754After diagnosis and treatment of breast cance

Beating cancer-related fatigue with personalized interventions

byUniversity of TwenteFlow diagram of selection of eligible studies. Credit:European Journal of Cancer Care(2022). DOI: 10.1111/ecc.13754After diagnosis and treatment of breast cance
Boosting anti-cancer antibodies by reducing their grip

Boosting anti-cancer antibodies by reducing their grip

byUniversity of SouthamptonIllustration of antibodies binding receptors and stimulating them. Credit: University of SouthamptonNew research from the Centre for Cancer Immunology at the Universit

Boosting anti-cancer antibodies by reducing their grip

byUniversity of SouthamptonIllustration of antibodies binding receptors and stimulating them. Credit: University of SouthamptonNew research from the Centre for Cancer Immunology at the Universit
Fighting cancer with a combination of corticosteroids and the keto diet

Fighting cancer with a combination of corticosteroids and the keto diet

byCold Spring Harbor LaboratoryIn mice with pancreatic and colorectal cancer, keto diets slow the growth of tumors, seen here in white, by a process called ferroptosis. This kills the cancer cel

Fighting cancer with a combination of corticosteroids and the keto diet

byCold Spring Harbor LaboratoryIn mice with pancreatic and colorectal cancer, keto diets slow the growth of tumors, seen here in white, by a process called ferroptosis. This kills the cancer cel
Promotion of cancer progression via extracellular vesicles

Promotion of cancer progression via extracellular vesicles

by Tokyo Medical and Dental UniversityUsually, blood vessels are stabilized, and their barrier function is maintained by the tight adhesion between vascular endothelial cells (①). When cancer cells me

Promotion of cancer progression via extracellular vesicles

by Tokyo Medical and Dental UniversityUsually, blood vessels are stabilized, and their barrier function is maintained by the tight adhesion between vascular endothelial cells (①). When cancer cells me