Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024 3

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024 3

Gut could sound early warning alarm for motor neuron disease

by University of AberdeenCredit: Pixabay/CC0 Public DomainThe same proteins thought to contribute to motor neuron disease can be found in the gut many years before any brain symptoms occur, a new

Updated on: February 03,2024 11

Gut could sound early warning alarm for motor neuron disease

by University of AberdeenCredit: Pixabay/CC0 Public DomainThe same proteins thought to contribute to motor neuron disease can be found in the gut many years before any brain symptoms occur, a new

Updated on:February 03,2024 11

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on: January 12,2024 10

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on:January 12,2024 10

Brain ripples may help bind information across the human cortex

by University of California - San DiegoCortical ripple generation during NREM and waking. (A) Average broadband LFP (i) and time-frequency (ii) across cortical ripples and example broadband rippl

Updated on: February 21,2024 10

Brain ripples may help bind information across the human cortex

by University of California - San DiegoCortical ripple generation during NREM and waking. (A) Average broadband LFP (i) and time-frequency (ii) across cortical ripples and example broadband rippl

Updated on:February 21,2024 10

Hypertension drug may hold promise for Alzheimer's disease

by American Heart AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainSeeking new treatments to slow the progression of Alzheimer's disease, researchers fo

Updated on: June 04,2024 5

Hypertension drug may hold promise for Alzheimer's disease

by American Heart AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainSeeking new treatments to slow the progression of Alzheimer's disease, researchers fo

Updated on:June 04,2024 5

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on: March 25,2024 11

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on:March 25,2024 11

Experiments on mice reveal the parts of the brain involved in motion sickness

by Bob Yirka , Medical XpressIdentification of glutamatergic neuronal subpopulations in the VN. (A)Slc17a6Cremice were bilaterally injected in the VN with a viral vector expressing the Rib

Updated on: January 11,2024 10

Experiments on mice reveal the parts of the brain involved in motion sickness

by Bob Yirka , Medical XpressIdentification of glutamatergic neuronal subpopulations in the VN. (A)Slc17a6Cremice were bilaterally injected in the VN with a viral vector expressing the Rib

Updated on:January 11,2024 10

Study suggests marijuana use damages brain immune cells vital to adolescent development

byJohns Hopkins University School of MedicineCnr1 expression in the microglia of the mouse brain.aExperimental flow of Fluorescence-Activated Cell Sorting (FACS)-based microglia (CD4

Updated on: January 12,2024 17

Study suggests marijuana use damages brain immune cells vital to adolescent development

byJohns Hopkins University School of MedicineCnr1 expression in the microglia of the mouse brain.aExperimental flow of Fluorescence-Activated Cell Sorting (FACS)-based microglia (CD4

Updated on:January 12,2024 17

How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on: January 12,2024 20

How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on:January 12,2024 20

Three-minute test detects common form of dementia that's hard to diagnose

by Florida Atlantic UniversityJames E. Galvin, M.D., M.P.H., one of the most prominent neuroscientists in the country, and a professor in FAU's Charles E. Schmidt College of Medicine and Chri

Updated on: February 26,2024 15

Three-minute test detects common form of dementia that's hard to diagnose

by Florida Atlantic UniversityJames E. Galvin, M.D., M.P.H., one of the most prominent neuroscientists in the country, and a professor in FAU's Charles E. Schmidt College of Medicine and Chri

Updated on:February 26,2024 15

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on: April 18,2024 19

Early diagnosis of Alzheimer's: Ultra-long protein fibrils give clues on dementia risk

by Swiss Federal Laboratories for Materials Science and TechnologyAtomic force microscopy: Peter Nirmalraj investigates Alzheimer's disease at the nanometer scale. Credit: EmpaThe early detec

Updated on:April 18,2024 19

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on: May 17,2024 8

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on:May 17,2024 8