New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on: February 27,2024 16

New memory drug moves into Phase 1 clinical study

by National Institutes of HealthAn experimental drug that may improve memory is now being tested in a Phase 1 safety trial. The compound, BPN14770, was developed by Tetra Discovery Partners, with

Updated on:February 27,2024 16

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on: March 26,2024 14

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on:March 26,2024 14

Successful extraction of Alzheimer's-type dementia finger-tapping pattern

by HitachiThe National Center for Geriatrics and Gerontology ("NCGG") in Japan has succeeded in identifying an index finger-thumb tapping pattern unique to Alzheimer's-type dementia thro

Updated on: May 06,2024 11

Successful extraction of Alzheimer's-type dementia finger-tapping pattern

by HitachiThe National Center for Geriatrics and Gerontology ("NCGG") in Japan has succeeded in identifying an index finger-thumb tapping pattern unique to Alzheimer's-type dementia thro

Updated on:May 06,2024 11

High LDL linked to early-onset Alzheimer's

by Veterans Affairs Research CommunicationsDr. Thomas Wingo and Dr. Aliza Wingo (foreground) lead a lab at the Atlanta VA and Emory University dedicated to understanding the genetic basis of Alzheimer

Updated on: May 22,2024 7

High LDL linked to early-onset Alzheimer's

by Veterans Affairs Research CommunicationsDr. Thomas Wingo and Dr. Aliza Wingo (foreground) lead a lab at the Atlanta VA and Emory University dedicated to understanding the genetic basis of Alzheimer

Updated on:May 22,2024 7

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on: February 24,2024 17

Cell-type-specific genetic risk contributes to distinct stages of Alzheimer's disease progression, finds study

by Brigham and Women's HospitalCell-type-specific Alzheimer’s disease polygenic risk scores (ADPRS).aA schematic of cell-type-specific PRS derivation.bAn UpSetR plot o

Updated on:February 24,2024 17

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on: April 07,2024 15

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on:April 07,2024 15

Depressive symptoms may hasten memory decline in older people

by University College LondonCredit: Unsplash/CC0 Public DomainDepressive symptoms are linked to subsequent memory decline in older people, while poorer memory is also linked to an increase in dep

Updated on: June 15,2024 4

Depressive symptoms may hasten memory decline in older people

by University College LondonCredit: Unsplash/CC0 Public DomainDepressive symptoms are linked to subsequent memory decline in older people, while poorer memory is also linked to an increase in dep

Updated on:June 15,2024 4

Exposure to traffic noise linked to higher dementia risk

by British Medical JournalCredit: Unsplash/CC0 Public DomainExposure to noise from traffic on roads and railways over a long period is associated with a higher risk of developing dementia, especi

Updated on: June 24,2024 5

Exposure to traffic noise linked to higher dementia risk

by British Medical JournalCredit: Unsplash/CC0 Public DomainExposure to noise from traffic on roads and railways over a long period is associated with a higher risk of developing dementia, especi

Updated on:June 24,2024 5

Brain regions identified that may play a role in breathing failure following seizures

by University of IowaResearchers identified a site in the amygdala critical to breathing loss following a seizure. The purple and blue region represents a probability map of the region linked to

Updated on: February 21,2024 17

Brain regions identified that may play a role in breathing failure following seizures

by University of IowaResearchers identified a site in the amygdala critical to breathing loss following a seizure. The purple and blue region represents a probability map of the region linked to

Updated on:February 21,2024 17

Analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics

by Liu Jia,Chinese Academy of SciencesStable real-time analysis of optical imaging of large-scale neuronal activities. a, FX design-based real-time analysis system for large-scale imaging, in co

Updated on: March 19,2024 17

Analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics

by Liu Jia,Chinese Academy of SciencesStable real-time analysis of optical imaging of large-scale neuronal activities. a, FX design-based real-time analysis system for large-scale imaging, in co

Updated on:March 19,2024 17

Carriers of Alzheimer's genetic marker have greater difficulty harnessing past knowledge

by Baycrest Centre for Geriatric CareDr. Claude Alain, a senior author on the paper and senior scientist at Baycrest's Rotman Research Institute. Credit: Provided by Baycrest.Adults carrying

Updated on: April 23,2024 19

Carriers of Alzheimer's genetic marker have greater difficulty harnessing past knowledge

by Baycrest Centre for Geriatric CareDr. Claude Alain, a senior author on the paper and senior scientist at Baycrest's Rotman Research Institute. Credit: Provided by Baycrest.Adults carrying

Updated on:April 23,2024 19

Chemical regulates light processing differently in the autistic and non-autistic eye, new study finds

by King's College LondonCredit: Pixabay/CC0 Public DomainKing's College London researchers have shown that the brain chemical GABA regulates activity in the retina of the eye in autistic

Updated on: April 06,2024 0

Chemical regulates light processing differently in the autistic and non-autistic eye, new study finds

by King's College LondonCredit: Pixabay/CC0 Public DomainKing's College London researchers have shown that the brain chemical GABA regulates activity in the retina of the eye in autistic

Updated on:April 06,2024 0