Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on: January 09,2024 10

Exploring the link between early life stress and maladaptive behavior across species

by Ingrid Fadelli , Medical XpressEarly life stressors induce long-term alterations in central mechanisms that drive appropriate social interactions. Being social species, most individuals gain pleasu

Updated on:January 09,2024 10

The genome guardian turns to the dark side: Opportunity for drug discovery against cancer?

by Publicase Comunicação CientíficaUnder normal conditions, native p53 protein is folded but when chemicals and/or high pressure are applied the protein may unfold and loose its 3D structure. Dur

Updated on: June 14,2024 6

The genome guardian turns to the dark side: Opportunity for drug discovery against cancer?

by Publicase Comunicação CientíficaUnder normal conditions, native p53 protein is folded but when chemicals and/or high pressure are applied the protein may unfold and loose its 3D structure. Dur

Updated on:June 14,2024 6

Large-scale analysis documents air pollution effects on brain regions associated with emotions

by Clara G. Zundel,The ConversationCredit: Unsplash/CC0 Public DomainPeople who breathe polluted air experience changes within the brain regions that control emotions, and as a result, they may

Updated on: February 18,2024 13

Large-scale analysis documents air pollution effects on brain regions associated with emotions

by Clara G. Zundel,The ConversationCredit: Unsplash/CC0 Public DomainPeople who breathe polluted air experience changes within the brain regions that control emotions, and as a result, they may

Updated on:February 18,2024 13

BIN1 deficit impairs brain cell communication, memory consolidation

by University of South FloridaGopal Thinakaran, PhD, of the University of South Florida Morsani College of Medicine, leads one of the few groups around the country studying BIN1 as a risk factor

Updated on: March 26,2024 20

BIN1 deficit impairs brain cell communication, memory consolidation

by University of South FloridaGopal Thinakaran, PhD, of the University of South Florida Morsani College of Medicine, leads one of the few groups around the country studying BIN1 as a risk factor

Updated on:March 26,2024 20

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on: January 11,2024 11

Clinical trial suggests ALS drug effective for treating spinal cord injuries

by Laurie Fickman,University of HoustonRiluzole trough and peak concentrations from Phase I and Phase II/III trials presented in waterfall plots. Credit:Journal of Neurotrauma(2023).

Updated on:January 11,2024 11

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024 13

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024 13

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on: March 14,2024 17

New insights into the development of Parkinson's disease in the brain might open the doors to new therapies

byTokyo Medical and Dental UniversityIn healthy condition, CHCHD2WT localizes in mitochondria. In pathogenic condition, mutant CHCHD2T61I mislocalizes to the cytosol and recruits Casein kinase 1

Updated on:March 14,2024 17

Anticoagulants fail to prevent unexplained strokes, clinical trial finds

by Columbia University Irving Medical CenterVisual Abstract.Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy. Credit:JAMA, (2024). doi:10.10

Updated on: May 21,2024 8

Anticoagulants fail to prevent unexplained strokes, clinical trial finds

by Columbia University Irving Medical CenterVisual Abstract.Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy. Credit:JAMA, (2024). doi:10.10

Updated on:May 21,2024 8

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on: April 27,2024 0

New atlas of mRNA variants captures inner workings of the brain

byWeill Cornell Medical CollegeSummary of mouse brain cell subtype assignments by age and region. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01616-4Investigators at We

Updated on:April 27,2024 0

Marriage may help stave off dementia

by British Medical JournalCredit: Jeff Belmonte / WikipediaMarriage may lower the risk of developing dementia, concludes a synthesis of the available evidence published online in theJournal

Updated on: June 11,2024 8

Marriage may help stave off dementia

by British Medical JournalCredit: Jeff Belmonte / WikipediaMarriage may lower the risk of developing dementia, concludes a synthesis of the available evidence published online in theJournal

Updated on:June 11,2024 8

Dial for tuning dopamine, environmental signals found in Parkinson's

by University of Alabama in TuscaloosaC. elegans, seen here as hundreds living on a plate viewed through the lens of a microscope, share roughly half their genes with humans. Credit: The Universi

Updated on: February 05,2024 20

Dial for tuning dopamine, environmental signals found in Parkinson's

by University of Alabama in TuscaloosaC. elegans, seen here as hundreds living on a plate viewed through the lens of a microscope, share roughly half their genes with humans. Credit: The Universi

Updated on:February 05,2024 20

Brain's sensitivity to different types of regret may impact mood disorders like depression

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainResearchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regre

Updated on: February 21,2024 8

Brain's sensitivity to different types of regret may impact mood disorders like depression

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainResearchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regre

Updated on:February 21,2024 8