The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on: February 21,2024 10

The brain's protein-destruction machine learns new tricks at synapses, potential target for neurological treatments

by Aarhus UniversityCredit: Pixabay/CC0 Public DomainScientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein cleara

Updated on:February 21,2024 10

How soon is soon enough to learn you have Alzheimer's?

by Alex Smith, Kaiser Health NewsPET scan of a human brain with Alzheimer's disease. Credit: public domainJose Belardo of Lansing, Kan., spent most of his career in the U.S. Public Health Service.

Updated on: May 28,2024 6

How soon is soon enough to learn you have Alzheimer's?

by Alex Smith, Kaiser Health NewsPET scan of a human brain with Alzheimer's disease. Credit: public domainJose Belardo of Lansing, Kan., spent most of his career in the U.S. Public Health Service.

Updated on:May 28,2024 6

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on: March 27,2024 0

Accumulation of 'junk proteins' identified as one cause of aging and possible source of ALS

byThe Spanish National Cancer Research CentreAccumulation of "junk proteins": normal cells (left) and cells subjected to the effect of the toxic arginine-rich protein (right). In the l

Updated on:March 27,2024 0

Intranasal delivery of MSCs provides hope for treating Alzheimer's disease

by AlphaMed PressIntranasal injection (IN) of preconditioned MSC-derived EVs (MSC-EVs) affects microglia activation in the brain of 3xTg-AD mice. The image shows the distribution of Iba-1+-microglia (

Updated on: April 29,2024 11

Intranasal delivery of MSCs provides hope for treating Alzheimer's disease

by AlphaMed PressIntranasal injection (IN) of preconditioned MSC-derived EVs (MSC-EVs) affects microglia activation in the brain of 3xTg-AD mice. The image shows the distribution of Iba-1+-microglia (

Updated on:April 29,2024 11

Neural circuit location of strong sense of discomfort found

byUppsala UniversityCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113328Researchers have identified a new neural circuit in the brain which produces a strong sense of discomf

Updated on: January 10,2024 7

Neural circuit location of strong sense of discomfort found

byUppsala UniversityCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113328Researchers have identified a new neural circuit in the brain which produces a strong sense of discomf

Updated on:January 10,2024 7

More human-like model of Alzheimer's better mirrors tangles in the brain

by Perelman School of Medicine at the University of PennsylvaniaCredit: Human Brain ProjectTangled up brain fibrils made up of a rogue protein known as tau are the hallmark of Alzheimer's dis

Updated on: June 05,2024 7

More human-like model of Alzheimer's better mirrors tangles in the brain

by Perelman School of Medicine at the University of PennsylvaniaCredit: Human Brain ProjectTangled up brain fibrils made up of a rogue protein known as tau are the hallmark of Alzheimer's dis

Updated on:June 05,2024 7

Pain is a major problem for individuals with traumatic brain injury, researchers say

byWolters Kluwer HealthCredit: Pixabay/CC0 Public DomainChronic pain affects approximately 60% of people living with traumatic brain injury (TBI), even up to 30 years after injury, according to&

Updated on: January 09,2024 13

Pain is a major problem for individuals with traumatic brain injury, researchers say

byWolters Kluwer HealthCredit: Pixabay/CC0 Public DomainChronic pain affects approximately 60% of people living with traumatic brain injury (TBI), even up to 30 years after injury, according to&

Updated on:January 09,2024 13

Study suggests optogenetics can drive muscle contraction with greater control, less fatigue than electrical stimulation

byMassachusetts Institute of TechnologyMIT researchers have developed a way to help people with amputation or paralysis regain limb control. Instead of using electricity to stimulate muscles, th

Updated on: May 30,2024 0

Study suggests optogenetics can drive muscle contraction with greater control, less fatigue than electrical stimulation

byMassachusetts Institute of TechnologyMIT researchers have developed a way to help people with amputation or paralysis regain limb control. Instead of using electricity to stimulate muscles, th

Updated on:May 30,2024 0

How the brain coordinates speaking and breathing

by Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT researchers have discovered a brain circuit that drives vocalization and ensures that you talk only when you breathe o

Updated on: March 19,2024 20

How the brain coordinates speaking and breathing

by Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT researchers have discovered a brain circuit that drives vocalization and ensures that you talk only when you breathe o

Updated on:March 19,2024 20

'I know that you know'—5 ways to help people with aphasia to communicate

by Deborah Hersh,The ConversationCredit: AI-generated imageAphasia was in the news last week when the family of actor Bruce Willis announced he was stepping back from his career due to communica

Updated on: January 21,2024 20

'I know that you know'—5 ways to help people with aphasia to communicate

by Deborah Hersh,The ConversationCredit: AI-generated imageAphasia was in the news last week when the family of actor Bruce Willis announced he was stepping back from his career due to communica

Updated on:January 21,2024 20

4D printing allows flexible electrodes for nerve stimulation

byTechnical University MunichFor the conductive structures, a thin layer of gold is deposited onto the 3D printed structure under high vacuum. Credit: Andreas Heddergott / TUMSpecific nerves may

Updated on: January 21,2024 10

4D printing allows flexible electrodes for nerve stimulation

byTechnical University MunichFor the conductive structures, a thin layer of gold is deposited onto the 3D printed structure under high vacuum. Credit: Andreas Heddergott / TUMSpecific nerves may

Updated on:January 21,2024 10

Common viruses may be triggering the onset of Alzheimer's disease

by Tufts UniversityVaricella zoster virus (VZV), which commonly causes chickenpox and shingles, activates herpes simplex virus (HSV) from dormancy in neural tissue grown in vitro, which then lead

Updated on: May 05,2024 14

Common viruses may be triggering the onset of Alzheimer's disease

by Tufts UniversityVaricella zoster virus (VZV), which commonly causes chickenpox and shingles, activates herpes simplex virus (HSV) from dormancy in neural tissue grown in vitro, which then lead

Updated on:May 05,2024 14