New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on: March 25,2024 6

New drugs cross blood-brain barrier to slow progression and even reverse symptoms of Huntington's disease

FEBRUARY 26, 2024byWeizmann Institute of ScienceCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-023-00020-yWeizmann Institute scientists have discovered two small molecules

Updated on:March 25,2024 6

Newly discovered genetic variant that causes Parkinson's disease clarifies why the condition develops and how to halt it

by Matthew Farrer,The ConversationSchematic outline of the methodological framework used in the study. Credit:The Lancet Neurology(2024). DOI: 10.1016/S1474-4422(24)00121-2Parkinson&

Updated on: April 27,2024 0

Newly discovered genetic variant that causes Parkinson's disease clarifies why the condition develops and how to halt it

by Matthew Farrer,The ConversationSchematic outline of the methodological framework used in the study. Credit:The Lancet Neurology(2024). DOI: 10.1016/S1474-4422(24)00121-2Parkinson&

Updated on:April 27,2024 0

Prolonging the effects of botulinum therapy: A milestone in neuromuscular disease management

by Shimane UniversityAntibody administration following saline or BTX administration at the beginning of the treatment. Anti-IGF1R antibody treatment is denoted as IGF1R and control IgG antibody treatm

Updated on: January 10,2024 12

Prolonging the effects of botulinum therapy: A milestone in neuromuscular disease management

by Shimane UniversityAntibody administration following saline or BTX administration at the beginning of the treatment. Anti-IGF1R antibody treatment is denoted as IGF1R and control IgG antibody treatm

Updated on:January 10,2024 12

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on: March 20,2024 13

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on:March 20,2024 13

Research team builds first tandem repeat expansions genetic reference maps

by Pat Harriman,University of California, IrvineGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.004A research team led by the University of California, Irvine has

Updated on: April 06,2024 0

Research team builds first tandem repeat expansions genetic reference maps

by Pat Harriman,University of California, IrvineGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.004A research team led by the University of California, Irvine has

Updated on:April 06,2024 0

Study reveals broader impact of Alzheimer's on brain function

by Stephen Fontenot,University of Texas at DallasAlzheimer's disease and aging are associated with distinct patterns of brain network disruption. Alzheimer's (left) exerts widespread imp

Updated on: January 10,2024 13

Study reveals broader impact of Alzheimer's on brain function

by Stephen Fontenot,University of Texas at DallasAlzheimer's disease and aging are associated with distinct patterns of brain network disruption. Alzheimer's (left) exerts widespread imp

Updated on:January 10,2024 13

New brain alterations induced by main genetic risk factor in Alzheimer's disease discovered

by Autonomous University of BarcelonaCultured APOE4 astrocytes with altered lipid accumulation. Credit: INc-UABA study led by the Institut de Neurociències (INc-UAB) shows that APOE4, the princip

Updated on: May 28,2024 5

New brain alterations induced by main genetic risk factor in Alzheimer's disease discovered

by Autonomous University of BarcelonaCultured APOE4 astrocytes with altered lipid accumulation. Credit: INc-UABA study led by the Institut de Neurociències (INc-UAB) shows that APOE4, the princip

Updated on:May 28,2024 5

Advancing high-resolution ultrasound imaging with deep learning

by Elizabeth Bello, Beckman Institute for Advanced Science and TechnologyLooking at an ultrasound image, Shin points to a region of the brain showing strong microbubble activity from a nerve stimulati

Updated on: May 14,2024 0

Advancing high-resolution ultrasound imaging with deep learning

by Elizabeth Bello, Beckman Institute for Advanced Science and TechnologyLooking at an ultrasound image, Shin points to a region of the brain showing strong microbubble activity from a nerve stimulati

Updated on:May 14,2024 0

Why poor sleep quality can be a matter of life and death for migrant roofers

by Amy McCaig,Rice UniversityCredit: Pixabay/CC0 Public DomainMigrant roofers in the U.S. helping communities rebuild from natural disasters often struggle with poor quality of sleep, according

Updated on: March 21,2024 15

Why poor sleep quality can be a matter of life and death for migrant roofers

by Amy McCaig,Rice UniversityCredit: Pixabay/CC0 Public DomainMigrant roofers in the U.S. helping communities rebuild from natural disasters often struggle with poor quality of sleep, according

Updated on:March 21,2024 15

Blacks are at higher risk for Alzheimer's, but why?

by Renã A.s. Robinson,The ConversationCredit: CC0 Public DomainBlacks are at higher risk for several health conditions in the U.S. This is true for heart disease, hypertension, type 2 diabetes a

Updated on: June 07,2024 5

Blacks are at higher risk for Alzheimer's, but why?

by Renã A.s. Robinson,The ConversationCredit: CC0 Public DomainBlacks are at higher risk for several health conditions in the U.S. This is true for heart disease, hypertension, type 2 diabetes a

Updated on:June 07,2024 5

Researchers find that youthful proteins help nerves regrow

by Kim Krieger,University of ConnecticutThree sections of optic nerve were injured by crushing (the white diamond on the far left of each nerve marks the crush point.) The lower two nerves each

Updated on: January 11,2024 16

Researchers find that youthful proteins help nerves regrow

by Kim Krieger,University of ConnecticutThree sections of optic nerve were injured by crushing (the white diamond on the far left of each nerve marks the crush point.) The lower two nerves each

Updated on:January 11,2024 16

Researchers find possible neuromarker for 'juvenile-onset' Batten disease

by Kelsie Smith Hayduk,University of Rochester Medical CenterMeanMMN amplitude for each SOA in TD and CLN3 disease groups. Each scatter plot, box plot, and violin plot column represents in

Updated on: January 09,2024 5

Researchers find possible neuromarker for 'juvenile-onset' Batten disease

by Kelsie Smith Hayduk,University of Rochester Medical CenterMeanMMN amplitude for each SOA in TD and CLN3 disease groups. Each scatter plot, box plot, and violin plot column represents in

Updated on:January 09,2024 5