Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024 14

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024 14

Drug linked to lower risk of dementia in people with diabetes

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with diabetes are twice as likely to develop dementia as those without the disease. In a new study, people with newly diagn

Updated on: June 24,2024 7

Drug linked to lower risk of dementia in people with diabetes

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople with diabetes are twice as likely to develop dementia as those without the disease. In a new study, people with newly diagn

Updated on:June 24,2024 7

Women more severely affected by Alzheimer's than men

by University of HertfordshireWomen with Alzheimer's have poorer cognitive abilities than men at the same stage of the disease, reveal academics from the University of Hertfordshire in a pape

Updated on: February 28,2024 19

Women more severely affected by Alzheimer's than men

by University of HertfordshireWomen with Alzheimer's have poorer cognitive abilities than men at the same stage of the disease, reveal academics from the University of Hertfordshire in a pape

Updated on:February 28,2024 19

Unraveling Alzheimer's: New study documents how brain cells go bad

by University of North Carolina Health CareNeurons treated with Alzheimer's-associated proteins exhibit drastic calcium increases (blue, green, yellow, red to white), and the cells form tau-f

Updated on: July 01,2024 3

Unraveling Alzheimer's: New study documents how brain cells go bad

by University of North Carolina Health CareNeurons treated with Alzheimer's-associated proteins exhibit drastic calcium increases (blue, green, yellow, red to white), and the cells form tau-f

Updated on:July 01,2024 3

Estrogen drug may not benefit women with Alzheimer's dementia

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.An estrogen-like drug, raloxifene, has no demonstrated benefit on me

Updated on: February 26,2024 15

Estrogen drug may not benefit women with Alzheimer's dementia

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.An estrogen-like drug, raloxifene, has no demonstrated benefit on me

Updated on:February 26,2024 15

Researchers use AI-powered method to identify genetic epilepsies earlier than current genetic diagnosis

byChildren's Hospital of PhiladelphiaCredit: CC0 Public DomainDiagnosing the genetic cause of a disease can aid in finding therapies and directing treatment, but often these diagnoses occur

Updated on: August 08,2024 0

Researchers use AI-powered method to identify genetic epilepsies earlier than current genetic diagnosis

byChildren's Hospital of PhiladelphiaCredit: CC0 Public DomainDiagnosing the genetic cause of a disease can aid in finding therapies and directing treatment, but often these diagnoses occur

Updated on:August 08,2024 0

Racial disparities in drug prescriptions for dementia

by University College LondonCredit: CC0 Public DomainDisparities in drug prescribing suggest that black and Asian people with dementia are not receiving the same quality of care as their white pe

Updated on: May 11,2024 5

Racial disparities in drug prescriptions for dementia

by University College LondonCredit: CC0 Public DomainDisparities in drug prescribing suggest that black and Asian people with dementia are not receiving the same quality of care as their white pe

Updated on:May 11,2024 5

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on: April 01,2024 18

P-glycoprotein removes Alzheimer's-associated toxin from the brain

by Southern Methodist University(A) The first frame of SMU's simulation shows amyloid-β bound to the drug binding domains of P-gp. (B) The final frame of the same simulation shows P-gp pushin

Updated on:April 01,2024 18

Alzheimer's more versatile than previously known

by Lund UniversityThe illuminated spotes (red, yellow and green) indicate an accumulation of the protein beta-amyloid. The top row shows the brain of a patient diagnosed with Alzheimer's dise

Updated on: February 28,2024 20

Alzheimer's more versatile than previously known

by Lund UniversityThe illuminated spotes (red, yellow and green) indicate an accumulation of the protein beta-amyloid. The top row shows the brain of a patient diagnosed with Alzheimer's dise

Updated on:February 28,2024 20

Gene defect may point to solution for Alzheimer's

by University of BergenLaurence Bindoff (picture) and Janniche Torsvik have studied the connection between the protein (PITRM1) and neurodegeneration in order to create new medicines to fight Alz

Updated on: February 28,2024 18

Gene defect may point to solution for Alzheimer's

by University of BergenLaurence Bindoff (picture) and Janniche Torsvik have studied the connection between the protein (PITRM1) and neurodegeneration in order to create new medicines to fight Alz

Updated on:February 28,2024 18

Sleep deprivation in mice found to reduce brain synapse diversity

by Bob Yirka , Medical XpressCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.032A multi-disciplinary team has found that depriving lab mice of sleep can lead to a reduction in syn

Updated on: August 08,2024 0

Sleep deprivation in mice found to reduce brain synapse diversity

by Bob Yirka , Medical XpressCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.032A multi-disciplinary team has found that depriving lab mice of sleep can lead to a reduction in syn

Updated on:August 08,2024 0

Hope for Alzheimer's blood test

by Macquarie UniversityBoxplots comparing plasma Aβ1-42/Aβ1-40 ratio, p-tau181, GFAP, and NfL between CU Aβ−, CU Aβ+, MCI Aβ−, MCI Aβ+, and AD Aβ+ groups at timepoint 1. Plasma measures were comp

Updated on: March 30,2024 13

Hope for Alzheimer's blood test

by Macquarie UniversityBoxplots comparing plasma Aβ1-42/Aβ1-40 ratio, p-tau181, GFAP, and NfL between CU Aβ−, CU Aβ+, MCI Aβ−, MCI Aβ+, and AD Aβ+ groups at timepoint 1. Plasma measures were comp

Updated on:March 30,2024 13