Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on: June 20,2024 3

Aβ43 generation in familial Alzheimer's disease: New insights into disease onset

by Doshisha UniversityIn this study, γ-secretase was extracted from wild type (WT) cells and cells carrying FAD-related genetic mutations (mutations in presenilin 1: L85P, I143T, H163R, L166P, G206V,

Updated on:June 20,2024 3

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on: March 27,2024 0

Immune cells identified as key players in brain health

byThe Mount Sinai HospitalThe Icahn Mount Sinai researchers nominated and validated transcription factors BHLHE40 and BHLHE41 that regulate clearance processes in immune cells, including brain i

Updated on:March 27,2024 0

Synapse discovery could lead to new treatments for Alzheimer's disease

by University of New South WalesDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A team of researchers led by UNSW Australia scientists has discovere

Updated on: February 27,2024 16

Synapse discovery could lead to new treatments for Alzheimer's disease

by University of New South WalesDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A team of researchers led by UNSW Australia scientists has discovere

Updated on:February 27,2024 16

What an animated taco reveals about curiosity and patience

byDuke UniversityCredit: Pixabay/CC0 Public DomainCuriosity paradoxically increases people's patience for an answer, while simultaneously making them more eager to hear it, finds a new study

Updated on: January 12,2024 12

What an animated taco reveals about curiosity and patience

byDuke UniversityCredit: Pixabay/CC0 Public DomainCuriosity paradoxically increases people's patience for an answer, while simultaneously making them more eager to hear it, finds a new study

Updated on:January 12,2024 12

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on: February 03,2024 12

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on:February 03,2024 12

Report highlights scale of dementia epidemic in Africa

by King's College LondonCredit: King's College LondonAlzheimer's Disease International (ADI) has published its first report on the impact of dementia in sub-Saharan Africa (SSA), at i

Updated on: April 29,2024 11

Report highlights scale of dementia epidemic in Africa

by King's College LondonCredit: King's College LondonAlzheimer's Disease International (ADI) has published its first report on the impact of dementia in sub-Saharan Africa (SSA), at i

Updated on:April 29,2024 11

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on: April 16,2024 20

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on:April 16,2024 20

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on: July 06,2024 0

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on:July 06,2024 0

Study maps brain wave disruptions affecting memory recall

by UT Southwestern Medical CenterTheta oscillations—brain waves associated with encoding memories—lessen in intensity with administration of a drug called scopolamine, according to a study by UT

Updated on: March 02,2024 12

Study maps brain wave disruptions affecting memory recall

by UT Southwestern Medical CenterTheta oscillations—brain waves associated with encoding memories—lessen in intensity with administration of a drug called scopolamine, according to a study by UT

Updated on:March 02,2024 12

Make this Halloween a safe one for people with dementia

by Cara MurezHalloween is often frightening for loved ones who have dementia, but there are ways to keep it safe and not scary."Halloween can be very challenging and stressful for someone with de

Updated on: February 24,2024 13

Make this Halloween a safe one for people with dementia

by Cara MurezHalloween is often frightening for loved ones who have dementia, but there are ways to keep it safe and not scary."Halloween can be very challenging and stressful for someone with de

Updated on:February 24,2024 13

New study finds a 67% increase in neurovascular imaging use for headache and dizziness in the emergency department

by Harvey L. Neiman Health Policy InstituteCredit: CC0 Public DomainNew research demonstrates that the use of CT angiography (CTA) for patients with headache or dizziness increased dramatically over f

Updated on: March 30,2024 13

New study finds a 67% increase in neurovascular imaging use for headache and dizziness in the emergency department

by Harvey L. Neiman Health Policy InstituteCredit: CC0 Public DomainNew research demonstrates that the use of CT angiography (CTA) for patients with headache or dizziness increased dramatically over f

Updated on:March 30,2024 13

Experts explore new approach to vaccine trials and pandemic preparedness

byUniversity of CologneExemplary setup of a VACCELERATE APT on vaccines. Credit:Infection(2024). DOI: 10.1007/s15010-024-02347-1An international consortium of experts led by Translat

Updated on: August 01,2024 0

Experts explore new approach to vaccine trials and pandemic preparedness

byUniversity of CologneExemplary setup of a VACCELERATE APT on vaccines. Credit:Infection(2024). DOI: 10.1007/s15010-024-02347-1An international consortium of experts led by Translat

Updated on:August 01,2024 0