Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024 9

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024 9

Using focused ultrasound to treat Alzheimer's and Parkinson's

by Holly Evarts,Columbia University School of Engineering and Applied ScienceMRI and PET scans of an Alzheimer's patient receiving FUS in a small region of the brain (A) with MRI scans deter

Updated on: March 02,2024 14

Using focused ultrasound to treat Alzheimer's and Parkinson's

by Holly Evarts,Columbia University School of Engineering and Applied ScienceMRI and PET scans of an Alzheimer's patient receiving FUS in a small region of the brain (A) with MRI scans deter

Updated on:March 02,2024 14

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024 12

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024 12

Genetic changes implicated in altered Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainToday, researchers from UCL have presented more evidence that a gene, PSEN1, implicated in inherited, early-onset Alzheimer's disease is

Updated on: June 14,2024 5

Genetic changes implicated in altered Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainToday, researchers from UCL have presented more evidence that a gene, PSEN1, implicated in inherited, early-onset Alzheimer's disease is

Updated on:June 14,2024 5

Alzheimer's diagnosis, management improved by brain scans

by Alzheimer's AssociationAmyloid-positive (left) and amyloid-negative (right) PET scans can respectively be used to diagnose or rule out Alzheimer's disease in individuals with memory loss or

Updated on: April 25,2024 19

Alzheimer's diagnosis, management improved by brain scans

by Alzheimer's AssociationAmyloid-positive (left) and amyloid-negative (right) PET scans can respectively be used to diagnose or rule out Alzheimer's disease in individuals with memory loss or

Updated on:April 25,2024 19

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on: June 11,2024 7

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaDAXX (red color at top) prevents the aggregation of mutant p53 protein associated with cancers (dark green color at bottom) in cell

Updated on:June 11,2024 7

Brain scans reveal the hidden shape of thinking and predict students' learning better than test scores

byGeorgetown UniversityGeorgetown students gather around a computer during a Biology lab. Credit: Georgetown UniversityThe traditional tests and grades that educators have long used may measure

Updated on: February 21,2024 6

Brain scans reveal the hidden shape of thinking and predict students' learning better than test scores

byGeorgetown UniversityGeorgetown students gather around a computer during a Biology lab. Credit: Georgetown UniversityThe traditional tests and grades that educators have long used may measure

Updated on:February 21,2024 6

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on: March 26,2024 17

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on:March 26,2024 17

Can traditional chinese medicine offer treatments for dementia and Alzheimer's disease?

A new study of classical Chinese medical texts identifies references to age-related memory impairment similar to modern-day Alzheimer's disease, and to several plant-based ingredients used centuri

Updated on: March 07,2024 17

Can traditional chinese medicine offer treatments for dementia and Alzheimer's disease?

A new study of classical Chinese medical texts identifies references to age-related memory impairment similar to modern-day Alzheimer's disease, and to several plant-based ingredients used centuri

Updated on:March 07,2024 17

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on: February 05,2024 14

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on:February 05,2024 14

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on: April 10,2024 10

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on:April 10,2024 10

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on: March 28,2024 0

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on:March 28,2024 0