Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024 13

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024 13

Giving common muscle relaxant via nose shows potential to treat neurodegenerative diseases

by Perelman School of Medicine at the University of PennsylvaniaPET scan of a human brain with Alzheimer's disease. Credit: public domainDelivering the medication dantrolene through the nose

Updated on: July 01,2024 6

Giving common muscle relaxant via nose shows potential to treat neurodegenerative diseases

by Perelman School of Medicine at the University of PennsylvaniaPET scan of a human brain with Alzheimer's disease. Credit: public domainDelivering the medication dantrolene through the nose

Updated on:July 01,2024 6

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024 20

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024 20

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on: March 02,2024 20

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on:March 02,2024 20

Snake venom may hold key to breaking down plaques that cause Alzheimer's disease

by Monash UniversityA toxic protein called amyloid beta is thought to play a key role in the onset of Alzheimer's disease. In healthy people, amyloid beta is degraded by enzymes as it forms.

Updated on: February 28,2024 17

Snake venom may hold key to breaking down plaques that cause Alzheimer's disease

by Monash UniversityA toxic protein called amyloid beta is thought to play a key role in the onset of Alzheimer's disease. In healthy people, amyloid beta is degraded by enzymes as it forms.

Updated on:February 28,2024 17

Dirt can modulate the pathology in Alzheimer's disease

by Kyoto UniversityCredit: Kyoto UniversityEating well, exercising regularly, and having a satisfying social life are all crucial to staying healthy. Sometimes, however, it can be the tiniest thi

Updated on: June 11,2024 8

Dirt can modulate the pathology in Alzheimer's disease

by Kyoto UniversityCredit: Kyoto UniversityEating well, exercising regularly, and having a satisfying social life are all crucial to staying healthy. Sometimes, however, it can be the tiniest thi

Updated on:June 11,2024 8

The construction of visual attention highlighted at the neuronal level

byParis Brain InstituteAttention being caught. Credit: Mikhail Nilov.A giant billboard flashes on the side of a country road. Why does it catch our attention more easily than other details in th

Updated on: March 28,2024 0

The construction of visual attention highlighted at the neuronal level

byParis Brain InstituteAttention being caught. Credit: Mikhail Nilov.A giant billboard flashes on the side of a country road. Why does it catch our attention more easily than other details in th

Updated on:March 28,2024 0

Brain health: Seniors chat online to stay sharp

by Erik Robinson,Oregon Health & Science UniversityGene Gilmer, 90, participates in an online video chat clinical trial to see if regular conversation can stave off dementia, Feb. 6, 2019. G

Updated on: May 18,2024 8

Brain health: Seniors chat online to stay sharp

by Erik Robinson,Oregon Health & Science UniversityGene Gilmer, 90, participates in an online video chat clinical trial to see if regular conversation can stave off dementia, Feb. 6, 2019. G

Updated on:May 18,2024 8

Lost and found: Japan tags dementia sufferers with barcodes

A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.A company in Iruma, north

Updated on: March 07,2024 20

Lost and found: Japan tags dementia sufferers with barcodes

A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.A company in Iruma, north

Updated on:March 07,2024 20

Weight-loss drug may slow Alzheimer's decline

by Samantha Rey,Imperial College LondonCredit: Anna Shvets from PexelsA drug prescribed for diabetes and weight loss has been shown to reduce brain shrinkage in Alzheimer's patients by almos

Updated on: August 26,2024 0

Weight-loss drug may slow Alzheimer's decline

by Samantha Rey,Imperial College LondonCredit: Anna Shvets from PexelsA drug prescribed for diabetes and weight loss has been shown to reduce brain shrinkage in Alzheimer's patients by almos

Updated on:August 26,2024 0

Immune booster drugs meant to kill tumors found to improve Alzheimer's symptoms in mice

by Bob Yirka , Medical XpressCredit: martha sexton/public domain(MedicalXpress)—A team of researchers working at the Weizmann Institute of Science in Israel has found that a type of drug meant to help

Updated on: February 27,2024 16

Immune booster drugs meant to kill tumors found to improve Alzheimer's symptoms in mice

by Bob Yirka , Medical XpressCredit: martha sexton/public domain(MedicalXpress)—A team of researchers working at the Weizmann Institute of Science in Israel has found that a type of drug meant to help

Updated on:February 27,2024 16

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on: June 24,2024 8

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on:June 24,2024 8