ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on: June 14,2024 7

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on:June 14,2024 7

Hidden financial dimensions affect people with cognitive decline and their care partners, report says

by The Gerontological Society of AmericaCredit: CC0 Public DomainIn planning for older adulthood, many people both fear and consistently underestimate the risk of Alzheimer's disease and related d

Updated on: April 29,2024 14

Hidden financial dimensions affect people with cognitive decline and their care partners, report says

by The Gerontological Society of AmericaCredit: CC0 Public DomainIn planning for older adulthood, many people both fear and consistently underestimate the risk of Alzheimer's disease and related d

Updated on:April 29,2024 14

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on: April 16,2024 14

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on:April 16,2024 14

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on: March 07,2024 15

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on:March 07,2024 15

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on: March 07,2024 15

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on:March 07,2024 15

BACE-Inhibitor successfully tested in Alzheimer's animal model

by Technical University MunichMarc Aurel Busche at the two-photon microscope, which allows to visualize nerve cells with high temporal and spatial resolution in the intact brain. Credit: Kurt Bau

Updated on: March 19,2024 13

BACE-Inhibitor successfully tested in Alzheimer's animal model

by Technical University MunichMarc Aurel Busche at the two-photon microscope, which allows to visualize nerve cells with high temporal and spatial resolution in the intact brain. Credit: Kurt Bau

Updated on:March 19,2024 13

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on: February 05,2024 5

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on:February 05,2024 5

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024 6

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024 6

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on: April 02,2024 20

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on:April 02,2024 20

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on: March 30,2024 11

Lecanemab: Experimental drug is a ray of hope for Alzheimer's disease

by Frederic Calon and Étienne Aumont,The ConversationCredit: AI-generated imageOn Nov. 30, Eisai and Biogen announced theresults of their latest phase 3 clinical trial in Alzheimer's d

Updated on:March 30,2024 11

Special properties of pneumococci affect their ability to cause meningitis

by Karolinska InstitutetCredit: AI-generated imageStructures on the surface of pneumococci determine the ability of these bacteria to enter the brain and cause severe infections, according to a p

Updated on: March 06,2024 19

Special properties of pneumococci affect their ability to cause meningitis

by Karolinska InstitutetCredit: AI-generated imageStructures on the surface of pneumococci determine the ability of these bacteria to enter the brain and cause severe infections, according to a p

Updated on:March 06,2024 19

Brain mechanism teaches mice to avoid bullies: Findings may offer insight into human social disorders

byNYU Langone HealthCredit: Martha Sexton/public domainLike humans, mice live in complex social groups, fight over territory and mates, and learn when it is safer to avoid certain opponents. Aft

Updated on: March 13,2024 4

Brain mechanism teaches mice to avoid bullies: Findings may offer insight into human social disorders

byNYU Langone HealthCredit: Martha Sexton/public domainLike humans, mice live in complex social groups, fight over territory and mates, and learn when it is safer to avoid certain opponents. Aft

Updated on:March 13,2024 4