Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on: April 20,2024 20

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on:April 20,2024 20

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on: February 05,2024 6

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on:February 05,2024 6

Hit the sleep 'sweet spot' to keep brain sharp

by Washington University School of MedicineCredit: CC0 Public DomainLike so many other good things in life, sleep is best in moderation. A multiyear study of older adults found that both short an

Updated on: May 13,2024 7

Hit the sleep 'sweet spot' to keep brain sharp

by Washington University School of MedicineCredit: CC0 Public DomainLike so many other good things in life, sleep is best in moderation. A multiyear study of older adults found that both short an

Updated on:May 13,2024 7

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on: February 26,2024 11

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on:February 26,2024 11

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on: March 30,2024 18

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on:March 30,2024 18

Researchers find preclinical evidence that a nasal immunotherapy may help treat Alzheimer's disease

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainAlzheimer's is a debilitating neurodegenerative and neuroinflammatory disease that is difficult to treat. Most existing th

Updated on: March 02,2024 15

Researchers find preclinical evidence that a nasal immunotherapy may help treat Alzheimer's disease

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainAlzheimer's is a debilitating neurodegenerative and neuroinflammatory disease that is difficult to treat. Most existing th

Updated on:March 02,2024 15

Routine brain scanning may improve clinical care for people with psychosis

by University of OxfordCredit: AI-generated imageRoutine brain scanning in people experiencing psychosis could help to identify underlying physical conditions that are causing their symptoms, acc

Updated on: February 05,2024 9

Routine brain scanning may improve clinical care for people with psychosis

by University of OxfordCredit: AI-generated imageRoutine brain scanning in people experiencing psychosis could help to identify underlying physical conditions that are causing their symptoms, acc

Updated on:February 05,2024 9

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on: April 20,2024 10

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on:April 20,2024 10

Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on: April 08,2024 16

Genetic risk factors for Alzheimer's disease may be detectable even in young adults

by American Academy of NeurologyCredit: CC0 Public DomainNew research shows that a genetic risk score may detect those at higher risk for Alzheimer's disease long before symptoms appear—even

Updated on:April 08,2024 16

Trials reveal that internet-based conversations help sustain brain function in older adults

by Brian Burns,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainSocial isolation has been linked to faster cognitive decline and an increased risk of developing dementia, although

Updated on: April 28,2024 0

Trials reveal that internet-based conversations help sustain brain function in older adults

by Brian Burns,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainSocial isolation has been linked to faster cognitive decline and an increased risk of developing dementia, although

Updated on:April 28,2024 0

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024 0

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024 0

New research explains how brain blood vessels are formed

by Université libre de BruxellesMmp25 as a regulator of brain-specific angiogenesis.a, The TC genotype in mosaic sprouts during brain vascular invasion (36 hpf,n = 23 sprouts) and tru

Updated on: April 06,2024 0

New research explains how brain blood vessels are formed

by Université libre de BruxellesMmp25 as a regulator of brain-specific angiogenesis.a, The TC genotype in mosaic sprouts during brain vascular invasion (36 hpf,n = 23 sprouts) and tru

Updated on:April 06,2024 0