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Medical research
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Novel PCSK9 inhibitor cut LDL cholesterol levels by more than half

Novel PCSK9 inhibitor cut LDL cholesterol levels by more than half

byAmerican College of CardiologyCredit: Pixabay/CC0 Public DomainAmong patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to s

Novel PCSK9 inhibitor cut LDL cholesterol levels by more than half

byAmerican College of CardiologyCredit: Pixabay/CC0 Public DomainAmong patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to s
Brain cell discovery sparks hope for fertility treatments

Brain cell discovery sparks hope for fertility treatments

byNagoya UniversityResearchers demonstrated kisspeptin neurons with dynorphin receptors in the brain affects the release of hormones that affect reproductive function in females. Credit: Mayuko

Brain cell discovery sparks hope for fertility treatments

byNagoya UniversityResearchers demonstrated kisspeptin neurons with dynorphin receptors in the brain affects the release of hormones that affect reproductive function in females. Credit: Mayuko
Drug candidate granted FDA orphan drug status for pancreatic cancer

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug
Can HIV be cured using gene editing? We may soon find out

Can HIV be cured using gene editing? We may soon find out

by Kalpana Surendranath,The ConversationCredit: Pixabay/CC0 Public DomainHIV, the virus that causes AIDS, was firstidentified in 1983. To catch this virus was initially a death sentence, b

Can HIV be cured using gene editing? We may soon find out

by Kalpana Surendranath,The ConversationCredit: Pixabay/CC0 Public DomainHIV, the virus that causes AIDS, was firstidentified in 1983. To catch this virus was initially a death sentence, b
Advances and challenges in gene therapy for rare diseases

Advances and challenges in gene therapy for rare diseases

by Kathryn Ryan,Mary Ann Liebert, IncThis stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is di

Advances and challenges in gene therapy for rare diseases

by Kathryn Ryan,Mary Ann Liebert, IncThis stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is di
Clinical trial shows rheumatoid arthritis drug could prevent disease

Clinical trial shows rheumatoid arthritis drug could prevent disease

by King's College LondonCredit: Unsplash/CC0 Public DomainA drug used to treat rheumatoid arthritis could also prevent the disease in individuals deemed to be at risk. Results from a Phase 2b

Clinical trial shows rheumatoid arthritis drug could prevent disease

by King's College LondonCredit: Unsplash/CC0 Public DomainA drug used to treat rheumatoid arthritis could also prevent the disease in individuals deemed to be at risk. Results from a Phase 2b
UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of medical researchers with affiliations to British multinational pharmaceutical and biotechnology company GlaxoSmithKline (GSK) ha

UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of medical researchers with affiliations to British multinational pharmaceutical and biotechnology company GlaxoSmithKline (GSK) ha
Who benefits from direct-to-consumer pharmaceutical advertising?

Who benefits from direct-to-consumer pharmaceutical advertising?

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainA new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommend

Who benefits from direct-to-consumer pharmaceutical advertising?

by University of Massachusetts AmherstCredit: Pixabay/CC0 Public DomainA new study co-authored by a University of Massachusetts Amherst economist reveals the value of government vaccine recommend
A novel strategy for cardiac repair using stem cell–derived progenitor cells and cell-seeding matrix patches

A novel strategy for cardiac repair using stem cell–derived progenitor cells and cell-seeding matrix patches

Graphical abstract. Credit:Bioactive Materials(2023). DOI: 10.1016/j.bioactmat.2023.05.015Myocardial infarction (MI) and the resulting heart failure remain a leading cause of morbidity and

A novel strategy for cardiac repair using stem cell–derived progenitor cells and cell-seeding matrix patches

Graphical abstract. Credit:Bioactive Materials(2023). DOI: 10.1016/j.bioactmat.2023.05.015Myocardial infarction (MI) and the resulting heart failure remain a leading cause of morbidity and
Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind
New study reveals unexpected consequences of CRISPR-Cas9 gene editing

New study reveals unexpected consequences of CRISPR-Cas9 gene editing

byKarolinska InstitutetSchematic illustration displays the workflow for determining the frequency of the genomic deletion of the PAPSS2-PTEN locus and associated cellular consequences in single-

New study reveals unexpected consequences of CRISPR-Cas9 gene editing

byKarolinska InstitutetSchematic illustration displays the workflow for determining the frequency of the genomic deletion of the PAPSS2-PTEN locus and associated cellular consequences in single-