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Medical research
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From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

byJohn Innes CentreCrystal structures of SAP05–SPL5ZnFand SAP05–Rpn10vWAcomplexes revealing the bimodular architecture of SAP05. (A) Cartoon model illustrating the fold of the

From infamy to ingenuity—bacterial hijack mechanisms as advanced genetic tools

byJohn Innes CentreCrystal structures of SAP05–SPL5ZnFand SAP05–Rpn10vWAcomplexes revealing the bimodular architecture of SAP05. (A) Cartoon model illustrating the fold of the
Scientists discover surprise anticancer properties of common lab molecule

Scientists discover surprise anticancer properties of common lab molecule

by UNC HealthIncorporation of thymidine analogs into the human genome and removal of EdU by nucleotide excision repair. (A) Chemical structure of thymidine analogs used in this study. (B) Slot blot as

Scientists discover surprise anticancer properties of common lab molecule

by UNC HealthIncorporation of thymidine analogs into the human genome and removal of EdU by nucleotide excision repair. (A) Chemical structure of thymidine analogs used in this study. (B) Slot blot as
Novel PCSK9 inhibitor cut LDL cholesterol levels by more than half

Novel PCSK9 inhibitor cut LDL cholesterol levels by more than half

byAmerican College of CardiologyCredit: Pixabay/CC0 Public DomainAmong patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to s

Novel PCSK9 inhibitor cut LDL cholesterol levels by more than half

byAmerican College of CardiologyCredit: Pixabay/CC0 Public DomainAmong patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to s
Research offers new insights into how breakdown of omega-6 fatty acids influences metabolism

Research offers new insights into how breakdown of omega-6 fatty acids influences metabolism

by Eva Maria Wellnitz, Universitätsmedizin MannheimGeneration and validation of aldh9a1b−/- zebrafish line using CRISPR/Cas9 technology (A) Neighbor-joining phylogenetic bootstrap tree of amino acid s

Research offers new insights into how breakdown of omega-6 fatty acids influences metabolism

by Eva Maria Wellnitz, Universitätsmedizin MannheimGeneration and validation of aldh9a1b−/- zebrafish line using CRISPR/Cas9 technology (A) Neighbor-joining phylogenetic bootstrap tree of amino acid s
Advances and challenges in gene therapy for rare diseases

Advances and challenges in gene therapy for rare diseases

by Kathryn Ryan,Mary Ann Liebert, IncThis stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is di

Advances and challenges in gene therapy for rare diseases

by Kathryn Ryan,Mary Ann Liebert, IncThis stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is di
Cost cutting may be behind high levels of lead in recalled applesauce products

Cost cutting may be behind high levels of lead in recalled applesauce products

by Physician's Briefing StaffThe U.S. Food and Drug Administration is currently investigating whether or not the cinnamon used in applesauce pouches that have been tied to high lead levels in chil

Cost cutting may be behind high levels of lead in recalled applesauce products

by Physician's Briefing StaffThe U.S. Food and Drug Administration is currently investigating whether or not the cinnamon used in applesauce pouches that have been tied to high lead levels in chil
New study lists potentially dangerous drugs in Australian health care

New study lists potentially dangerous drugs in Australian health care

by RMIT University'Potentially inappropriate medicines' (PIMs) include ibuprofen and codeine - pictured. Credit: RMIT University / Ant BragagliaResearchers have developed an Australian-fi

New study lists potentially dangerous drugs in Australian health care

by RMIT University'Potentially inappropriate medicines' (PIMs) include ibuprofen and codeine - pictured. Credit: RMIT University / Ant BragagliaResearchers have developed an Australian-fi
Experimental antibiotic treatment for Lyme disease heads for human safety trials

Experimental antibiotic treatment for Lyme disease heads for human safety trials

FEBRUARY 29, 2024by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Pixabay/CC0 Public DomainHuman safety trials of a novel antibiotic treatment for Lyme disease developed by Northeaste

Experimental antibiotic treatment for Lyme disease heads for human safety trials

FEBRUARY 29, 2024by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Pixabay/CC0 Public DomainHuman safety trials of a novel antibiotic treatment for Lyme disease developed by Northeaste
Study finds tafenoquine is a cost-effective treatment option for malaria

Study finds tafenoquine is a cost-effective treatment option for malaria

by Menzies School of Health ResearchMap of incremental cost-effectiveness ratios (ICERs) in each malaria-endemic municipality for Scenario 1 (tafenoquine for adults, primaquine adherence 66.7%),

Study finds tafenoquine is a cost-effective treatment option for malaria

by Menzies School of Health ResearchMap of incremental cost-effectiveness ratios (ICERs) in each malaria-endemic municipality for Scenario 1 (tafenoquine for adults, primaquine adherence 66.7%),
New study reveals unexpected consequences of CRISPR-Cas9 gene editing

New study reveals unexpected consequences of CRISPR-Cas9 gene editing

byKarolinska InstitutetSchematic illustration displays the workflow for determining the frequency of the genomic deletion of the PAPSS2-PTEN locus and associated cellular consequences in single-

New study reveals unexpected consequences of CRISPR-Cas9 gene editing

byKarolinska InstitutetSchematic illustration displays the workflow for determining the frequency of the genomic deletion of the PAPSS2-PTEN locus and associated cellular consequences in single-
Cannabis use linked to increase in heart attack and stroke risk

Cannabis use linked to increase in heart attack and stroke risk

FEBRUARY 28, 2024 Editors' notesbyAmerican Heart AssociationCredit: Unsplash/CC0 Public DomainAn analysis of 430,000 adults in the U.S. found that using cannabis, most commonly through smoki

Cannabis use linked to increase in heart attack and stroke risk

FEBRUARY 28, 2024 Editors' notesbyAmerican Heart AssociationCredit: Unsplash/CC0 Public DomainAn analysis of 430,000 adults in the U.S. found that using cannabis, most commonly through smoki