Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Updated on: March 14,2024 11

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Updated on:March 14,2024 11

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r

Updated on: March 25,2024 11

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r

Updated on:March 25,2024 11

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on: July 23,2024 0

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on:July 23,2024 0

Chronic Hepatitis B

RESEARCH29 January 2024New hepatitis B study reveals how viruses adapt to low-oxygen environments, such as those found deep within the liver, opening up possible new therapeutic targets for liver path

Updated on: March 11,2024 4

Chronic Hepatitis B

RESEARCH29 January 2024New hepatitis B study reveals how viruses adapt to low-oxygen environments, such as those found deep within the liver, opening up possible new therapeutic targets for liver path

Updated on:March 11,2024 4

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on: March 27,2024 0

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on:March 27,2024 0

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Updated on: March 13,2024 11

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Updated on:March 13,2024 11

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

Updated on: March 25,2024 16

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

Updated on:March 25,2024 16

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on: March 13,2024 5

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on:March 13,2024 5

Different autism risk genes, same effects on brain development

by Harvard UniversityMicroscopy image of a brain organoid showing neuron precursors (magenta) and deep-layer projection neurons (green), which are one of the cell types affected by autism risk ge

Updated on: February 05,2024 17

Different autism risk genes, same effects on brain development

by Harvard UniversityMicroscopy image of a brain organoid showing neuron precursors (magenta) and deep-layer projection neurons (green), which are one of the cell types affected by autism risk ge

Updated on:February 05,2024 17

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of

Updated on: October 28,2024 0

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of

Updated on:October 28,2024 0

Adding diversity to your research process: A new system

by Hoag Levins,University of PennsylvaniaCredit: University of PennsylvaniaInsufficient diversity in clinical trials and other research cohorts is widely recognized as one of American health car

Updated on: April 06,2024 0

Adding diversity to your research process: A new system

by Hoag Levins,University of PennsylvaniaCredit: University of PennsylvaniaInsufficient diversity in clinical trials and other research cohorts is widely recognized as one of American health car

Updated on:April 06,2024 0

Diabetes drug shows promise against Parkinson's in clinical study

by By Issam Ahmed and Lucie AubourgPeople play table tennis at the Ping Pong Parkinson initiative in Berlin on April 11, 2023, World Parkinson's Day -- the devastating disorder affects 10 million

Updated on: April 06,2024 0

Diabetes drug shows promise against Parkinson's in clinical study

by By Issam Ahmed and Lucie AubourgPeople play table tennis at the Ping Pong Parkinson initiative in Berlin on April 11, 2023, World Parkinson's Day -- the devastating disorder affects 10 million

Updated on:April 06,2024 0