HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

Updated on: March 14,2024 11

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

Updated on:March 14,2024 11

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur

Updated on: March 25,2024 8

Innovative therapies for ischemic stroke: Novel bicarbonate-sensing G protein-coupled receptor shows promise

FEBRUARY 27, 2024by Juntendo University Research Promotion CenterGPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neur

Updated on:March 25,2024 8

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear

Updated on: July 05,2024 0

New wearable patch measures trace perspiration during activity and rest

byUniversity of TsukubaConceptual illustration portrays fully assembled patch securely affixed to skin's surface. Credit:Advanced Science(2024). DOI: 10.1002/advs.202401947Resear

Updated on:July 05,2024 0

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on: March 30,2024 10

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Updated on:March 30,2024 10

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on: March 13,2024 13

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on:March 13,2024 13

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on: March 30,2024 0

Research suggests fine-tuning of specific excitatory synapse traits could lead to new brain disease treatments

by DGIST (Daegu Gyeongbuk Institute of Science and Technology)Profiling of LAR-RPTP microexon expression repertoires by targeted deep RNA sequencing Credit:Nature Communications(2024). DOI

Updated on:March 30,2024 0

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This

Updated on: April 06,2024 0

Pancreas cells in people who have died show significant signs of stress

by American Physiological SocietyCredit:Function(2024). DOI: 10.1093/function/zqae015People with type 1 diabetes require daily insulin shots to regulate their blood sugar levels. This

Updated on:April 06,2024 0

Study reveals potential to reverse lung fibrosis using the body's own healing technique

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172826The most common type of lung fibrosis—scarring of the lungs—is idiop

Updated on: April 28,2024 0

Study reveals potential to reverse lung fibrosis using the body's own healing technique

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172826The most common type of lung fibrosis—scarring of the lungs—is idiop

Updated on:April 28,2024 0

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on: March 25,2024 5

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on:March 25,2024 5

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on: April 28,2024 0

Study identifies novel mechanism of glucose sensing by adipocytes in regulating thermogenesis and energy metabolism

by Liu Jia,Chinese Academy of SciencesThe proposed model for glucose sensing via CREBZF in the regulation of thermogenesis and energy homeostasis in adipose tissues. Targeting CREBZF may provide

Updated on:April 28,2024 0

Researchers develop new tool to aid processing of spatial transcriptomic data

by Children's Hospital of PhiladelphiaThe network architecture of dependency-aware deep generative models. Credit:Nature Methods(2024). DOI: 10.1038/s41592-024-02257-yResearchers

Updated on: June 15,2024 6

Researchers develop new tool to aid processing of spatial transcriptomic data

by Children's Hospital of PhiladelphiaThe network architecture of dependency-aware deep generative models. Credit:Nature Methods(2024). DOI: 10.1038/s41592-024-02257-yResearchers

Updated on:June 15,2024 6

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur

Updated on: March 30,2024 8

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur

Updated on:March 30,2024 8